4.4 Article

Base-promoted selective β-fragmentation of homoallylamines

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 32, Pages 4275-4277

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.06.031

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Funding

  1. National Natural Science Foundation of China [20702006]
  2. Fudan University

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A selective beta-fragmentation of homoallylamines with the combination of iodobenzene diacetate, iodine, and sodium acetate is reported. The desired carbon-carbon bond cleavage proceeded via a radical beta-scission pathway under mild conditions with good functional group tolerance. (C) 2010 Elsevier Ltd. All rights reserved.

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