Review
Chemistry, Multidisciplinary
Ana B. Cuenca, Elena Fernandez
Summary: The boron-Wittig reaction involves the condensation of easy manageable lithium alpha-bis(boryl)carbanions with carbonyl derivatives to form metalloid-substituted alkenes, which are important building blocks for the synthesis of all-carbon substituted olefins. This reaction is stereoselective and can be applied to a variety of carbonyl derivatives, with a focus on controlling the stereochemical outcome. Its synthetic potential is demonstrated through applications to target compounds via subsequent C-C bond forming processes.
CHEMICAL SOCIETY REVIEWS
(2021)
Article
Chemistry, Organic
Koushik Patra, Mallu Kesava Reddy, Sumitava Mallik, Mahiuddin Baidya
Summary: The nucleophilic reactivity of alpha,alpha-difluorinated gem-diols has been utilized to selectively synthesize biologically relevant 1,4-dihydropyridines and 3,4-dihydro-2-pyridones adorned with the valuable gem-difluoromethylene motif. The method is scalable, high yielding, and compatible with a wide range of substrates and functional groups. Additionally, the synthesis of difluorinated oxa-azabicyclo [3.3.1] nonane frameworks has been demonstrated through product diversification.
Article
Chemistry, Organic
Javeed Ahmad Tali, Ravi Shankar
Summary: Here, we report an unprecedented protocol using ruthenium-catalyzed annulation for the synthesis of 6H-chromeno[4 ',3 ':4,5]imidazo[1,2-a]pyridin-6-one, and a new method for intramolecular chelation-assisted C-H activation to produce functionalized 2-(3-formylimidazo[1,2-a]pyridin-2-yl)phenyl acetate. Furthermore, a one-pot approach using ruthenium catalysis and formic acid has been developed for the gram-scale synthesis of bis(2-phenylimidazo[1,2-a]pyridin-3yl)methane (BIP) and the late-stage functionalization of zolimidine, a marketed drug, with good yield.
Article
Chemistry, Physical
Mark R. J. Elsegood, William Clegg, Carl Redshaw
Summary: The interaction between [VO(OiPr)(3)] and 6-bis(o-hydroxyaryl)pyridine, 2,6-{HOC(Ph)(2)CH2}(2)(NC5H3), LH2, resulted in the formation of [VO(OiPr)L] (1) with high yield. The reaction between LNa2, generated in-situ from LH2 and NaH, and [VCl3(THF)(3)] led to the isolation of [VL2] (2) with cis-pyridyl nitrogen atoms. In the case of [VCl2(TMEDA)(2)], a regioisomer 3.2THF with trans-pyridyl nitrogen atoms was obtained.
Article
Chemistry, Multidisciplinary
Maria Galiana-Cameo, Raul Romeo, Asier Urriolabeitia, Vincenzo Passarelli, Jesus J. Perez-Torrente, Victor Polo, Ricardo Castarlenas
Summary: The dinuclear complex [Rh(eta-C1)(eta(2)-coe)(IPr)](2) serves as an efficient catalyst for the O-selective Markovnikov-type addition of 2-pyridones to terminal alkynes. DFT calculations suggest a hydride-free pathway involving intramolecular oxidative protonation of a pi-alkyne by a kappa N-1-hydroxypyridine ligand. The release of the alkenyl ether is considered the rate-determining step in the reaction.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Crystallography
Peng-Fu Gao, Ting Li, Hong-Ru Fu
Summary: This is a triclinic compound with the chemical formula C82H48Cd2N4O8. The cell parameters are a = 7.6031(3) Å, b = 10.6963(3) Å, c = 19.0717(7) Å, with angles alpha = 98.967(3)°, beta = 99.207(3)°, gamma = 95.921(3)°. The cell volume is V = 1499.21(9) Å^3. The lattice parameters are R-gt(F) = 0.0396, wR(ref)(F-2) = 0.0802, and the temperature is T = 293(2) K.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
(2023)
Article
Crystallography
Peng-Fu Gao, Ting Li, Hong-Ru Fu
Summary: These are data about the crystal structure of a certain substance, including cell parameters and crystallographic angle parameters.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
(2023)
Article
Biochemistry & Molecular Biology
Igor A. Nikovskiy, Pavel V. Dorovatovskii, Valentin V. Novikov, Yulia V. Nelyubina
Summary: Two coordination polymers were obtained through a PCET-assisted process using the hydroxy-pyrazolyl moiety of the ligand and the iron(II) ion as sources of proton and electron. Under mild conditions, the first coordination polymer of 2,6-bis(pyrazol-3-yl)pyridines was synthesized. Under harsh solvothermal conditions, a hydrogen atom transfer resulted in the transformation of hydroxyl groups, producing the third coordination polymer of 2,6-bis(pyrazol-3-yl)pyridines. This PCET-assisted approach can be used to produce coordination polymers and metal-organic frameworks with the SCO-active core N-3(L)MN3(L).
Article
Chemistry, Multidisciplinary
Shoki Hoshikawa, Hikaru Yanai, Takashi Matsumoto
Summary: A simplified method for the synthesis of spiro[cyclobutene-1,9'-fluorene] compounds from biaryl-alkynes and 2-(2-fluoropyridin-1-ium-1-yl)-1,1-bis((trifluoromethyl)sulfonyl)ethan-1-ide has been developed, along with successful derivatization of triflylated spiro[cyclobutene-1,9'-fluorene] products.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Lukas Masaryk, Barbora Tesarova, Duane Choquesillo-Lazarte, Vedran Milosavljevic, Zbynek Heger, Pavel Kopel
Summary: In this study, a nickel(II) coordination compound with interesting biological behavior was synthesized, showing higher uptake by malignant cells, significant cytotoxicity differences, and the ability to hydrolyze DNA.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2021)
Article
Chemistry, Organic
Shangsheng Zhou, Yu Pu, Zhengli Liu, Xiaoming Zhang, Jiang Zhu, Zhang Feng
Summary: This study presents a novel iron-catalyzed reaction that efficiently converts unactivated gem-difluoroalkenes, gem-dichloroalkenes, and gem-dibromoalkenes into 1,2-bis(boryl)-alkanes with high selectivity and broad substrate applicability. Preliminary mechanistic studies suggest that double beta-F elimination plays a role in the catalytic cycle, with 1,1-diborylated alkenes potentially serving as intermediates in this iron-catalyzed 1,2-diborylation reaction.
Article
Crystallography
Dipendu Mandal, Georgina M. Rosair
Summary: The metalation of a thallium salt with nickel fragments resulted in the formation of bis(nickelated) products, which were characterized and identified as different stereospecific species. The study also demonstrated the achievement of new structures by utilizing different nickel fragments in the metalation process.
Article
Chemistry, Physical
Tatyana N. Moshkina, Emiliya V. Nosava, Alexandra E. Kopotilova, Maria I. Savchuk, Igor L. Nikonov, Dmitry S. Kopchuk, Igor A. Khalymbadzha, Pavel A. Slepukhin, Ilya N. Ganebnykh, Valery N. Charushin
Summary: In this study, two series of V-shaped 6,7-dihydro-5H-cyclopenta[c]pyridine chromophores bearing two 5-arylthiophen-2-yl fragments as well as pyridyl or quinolinyl residue were designed and synthesized. The basic photo-physical properties, metal cation detection ability, and halochromic properties of the compounds were investigated.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Jana Jurakova, Ondrej F. Fellner, Soren Schlittenhardt, Sarka Vavreckova, Ivan Nemec, Radovan Herchel, Erik Cizmar, Vinicius Tadeu Santana, Milan Orlita, Denis Gentili, Giampiero Ruani, Massimiliano Cavallini, Petr Neugebauer, Mario Ruben, Ivan Salitros
Summary: Two new hexacoordinated Co(II)-based single-ion magnets were synthesized and characterized. The complexes exhibited metal-centered coordination with nitrate anions and a 2,6-bis(1H-benzimidazole-2-yl)pyridine ligand with n-octyl or n-dodecyl chains. The presence of long aliphatic chains allowed for their solubility in low polarity and volatile solvents, enabling the preparation of microstructural layers and patterns on relevant substrates using wet lithographic techniques. The complexes displayed positive axial D parameters and showed field-induced slow relaxation of magnetization.
INORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Biochemistry & Molecular Biology
Meng Lian, Feng Zheng, Lingbin Meng, Fei Zhao, Jun Liu, Jimei Song, Qinghua Lu
Summary: This paper investigates the influence of heteroaromatic polyimides (PIs) containing benzimidazole on the properties of PIs. It was found that PIs containing benzimidazole exhibited better mechanical performance, lighter color, and higher glass transition temperature.
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)
