Journal
TETRAHEDRON LETTERS
Volume 51, Issue 22, Pages 2986-2989Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.03.125
Keywords
Marchantin C; Bisbibenzyl; Total synthesis; Natural products; Liverwort constituents
Categories
Funding
- Deutsche Forschungsgemeinschaft (DFG) [Sp 498/2-1]
Ask authors/readers for more resources
Recently, remarkable microtubule inhibitor and anti-tumor activities of the bisbibenzyl marchantin C-isolated from liverworts like Marchantia polymorpha since 1983-were found. In this Letter we describe the first and efficient total synthesis of this subtype of bisbibenzylic compounds with two biarylether connections. The structure was confirmed by the spectroscopic data which were analyzed carefully to exclude any errors in arene connection and substitution pattern. (C) 2010 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available