4.4 Article

Convenient synthesis of bis(indolyl)alkanes and bis(pyrrolyl)alkanes by Cu(OTf)2-catalyzed addition of indole and pyrrole to acetylenic sulfone

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 8, Pages 1213-1215

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.12.093

Keywords

Cu(OTf)(2); Michael addition; Bis(indolyl)alkanes; Bis(pyrrolyl)alkanes

Funding

  1. National Natural Science Foundation of China [20672001, 20772001]

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Sulfonyl-containing bis(indolyl)alkanes and bis(pyrrolyl)alkanes were synthesized conveniently by Cu(OTf)(2)-catalyzed double Michael addition of indole and pyrrole to acetylenic sulfone. (C) 2009 Elsevier Ltd. All rights reserved.

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