Article
Chemistry, Organic
Xiaoyi Zhu, Ruibo Li, Hequan Yao, Aijun Lin
Summary: The palladium-catalyzed allenamide carbopalladation/allylation reaction with active methine compounds resulted in the formation of indoles and isoquinolinones bearing a quaternary carbon center. This reaction demonstrated good efficiency, a broad substrate scope, and good functional group tolerance by forming two new C-C bonds in one pot.
Article
Chemistry, Organic
Jing-Xiang Xu, Kai-Ti Chu, Ming-Hsi Chiang, Jeng-Liang Han
Summary: A direct catalytic asymmetric functionalization of 2-methylindoles using organocatalysis was described. An efficient asymmetric allylic alkylation reaction with chiral biscinchona alkaloid catalyst provided functionalized indole derivatives in good yields and enantioselectivities.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Junkui Zhu, Honglie Shen, Zehui Wang, Yufang Li, Tianru Wu, Weibiao Mao, Jingzhe Zhang
Summary: In this work, high-quality vertical graphene nanowalls (VGN) were successfully prepared without catalysts through hot-wire chemical vapor deposition. The VGN exhibited low defect density, few layers, and submicron domain size. The prepared VGN showed excellent electrical properties and high output power in dropping-ion-droplet nano-power generation devices.
Article
Chemistry, Multidisciplinary
Yan Li, Suhashini Handunneththige, Jin Xiong, Yisong Guo, Marat R. Talipov, Dong Wang
Summary: In this work, a novel method to activate the C(sp3)-NH2 bond of primary alkylamines using a high-valent dinuclear CoIII,IV2(mu-O)2 diamond core complex was discovered. This reaction allows for the installation of functional groups onto the alpha-carbon center while oxidizing the nitrogen atom on the amino group to form NH2OH. These findings provide insights for future versatile functionalization of primary alkylamines based on the dinuclear cobalt system.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Physical
Zhenhua Li, Jinjia Liu, Run Shi, Geoffrey I. N. Waterhouse, Xiao-Dong Wen, Tierui Zhang
Summary: A series of novel Fe-based catalysts with different chemical compositions were successfully fabricated through hydrogen reduction, with Fe-500 exhibiting outstanding activity for CO2 photothermal conversion under UV-Vis irradiation. The density functional theory calculations improved the C-C coupling ability, enhancing the selectivity to C2+ products.
ADVANCED ENERGY MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Kun Yin, Yuguang Chao, Fan Lv, Lu Tao, Weiyu Zhang, Shiyu Lu, Menggang Li, Qinghua Zhang, Lin Gu, Hongbo Li, Shaojun Guo
Summary: This study presents the efficient electrosynthesis of high-value-added compound DEE and high-purity hydrogen using bifunctional catalysts PtIr nanowires. The catalysts exhibited lower voltage and higher Faraday efficiencies, promoting the activation of O-H and C-H bonds in ethanol for DEE production, showing great potential for wide application in electrosynthesis.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Medicinal
Lu Lin, Shunsuke Kataoka, Kiichi Hirayama, Ryozo Shibuya, Hiroyuki Morimoto, Takashi Ohshima
Summary: Catalytic control of chemoselectivity is crucial in the synthesis of highly functionalized compounds. In this study, highly O- and N-selective electrophilic activation of allylic alcohols and amines was achieved in Pd-catalyzed direct allylic alkylation. The N- selectivity is due to the selective activation of allylic amines with ammonium cations, and boronate formation accelerates the activation of allylic alcohols.
CHEMICAL & PHARMACEUTICAL BULLETIN
(2023)
Article
Chemistry, Physical
Max Roemer, Sinead T. Keaveney, Vinicius R. Goncales, Jiaxin Lian, James E. Downes, Shreedhar Gautam, J. Justin Gooding, Barbara A. Messerle
Summary: This study describes the synthesis and characterization of carbon black supported rhodium and iridium heterobimetallic catalysts, termed hybrid catalysts, and their application in the hydrosilylation of alkynes. The modification process results in efficient surface binding of Rh complexes, leading to alpha-selective product formation. Analysis through various techniques confirms the structure and performance of the hybrid catalysts.
CATALYSIS SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Taku Nakayama, Hidemasa Hikawa, Shoko Kikkawa, Isao Azumaya
Summary: A synthetic method for dehydrative N-benzylation promoted by water molecules in heptane using a pi-benzylpalladium system has been developed. The presence of water significantly accelerates carbon-nitrogen bond formation, which is accomplished in an atom-economical process to afford the corresponding N-monobenzylated products. Kinetic isotope effect measurements revealed that benzylic carbon-hydrogen bond cleavage was the rate-determining step.
Article
Multidisciplinary Sciences
Long Li, Shan Wang, Pengfei Luo, Ran Wang, Zheng Wang, Xiaoguang Li, Yuhua Deng, Fangzhi Peng, Zhihui Shao
Summary: The authors developed a method to synthesize quaternary carbon spirocycles in one step from 1,3-enynes and pyrazolidine-type heterocycles via palladium catalysis, which is important for drug discovery and development. Their approach involves a chiral Pd-hydride-catalyzed cycloaddition to control stereoselectivity and suppress by-product formation. The synthesis tolerates a wide range of functional groups and allows for flexible incorporation of diverse cyclic nucleophiles.
NATURE COMMUNICATIONS
(2021)
Article
Engineering, Chemical
Atsushi Takahashi, Tsutomu Chida, Kousuke Hiromori, Naomi Shibasaki-Kitakawa, Naoki Mimura, Aritomo Yamaguchi
Summary: A novel kinetic model was developed for the liquid-phase selective oxidation of glycerol over Au-supported catalysts. The model considers reactions in the bulk liquid phase, formation of reactive oxygen species on Au metal and support, and three reactions of different oxygen species. It enables optimization of reaction conditions and prediction of oxidation behavior, making it a useful tool for catalyst design and biomass conversion reaction conditions.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
Hui Song, Jinhua Ye
Summary: This review presents the latest advances in direct photocatalytic conversion of methane, focusing on the strategies for the rational design of photocatalysts to improve the activity and selectivity of the desired products. The current challenges and opportunities for further development of photocatalytic systems that enable highly selective and efficient conversion of methane to valuable chemicals are also discussed.
TRENDS IN CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Jiawen Wang, Faqian He, Xiaoyu Yang
Summary: Acyclic quaternary stereocenters are commonly found in biologically active natural products and pharmaceuticals. The development of an efficient chiral phosphoric acid catalyzed direct asymmetric addition method has allowed for the synthesis of acyclic all-carbon quaternary stereocenters with excellent regioselectivities and high enantioselectivities. The mechanism of this reaction involves a novel covalent allyl phosphate intermediate and asymmetric conjugate addition under chiral anion catalysis. Extensive experimental studies have provided access to a wide array of chiral scaffolds with quaternary stereocenters.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Organic
Gang Liu, Xianfeng Mu, Miao Tian, Weili Wang, Chunhui Zou, Yiwen Chen, Mingwu Yu
Summary: We developed a radical deoxy-functionalization strategy for direct C-H alkylation of purines and purine nucleosides with alcohols under blue LED irradiation. The reaction exhibited high regioselectivity and broad functional group tolerance. It provided a wide range of products in good yields, avoiding the use of transition metal catalysts and organometallic reagents.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Environmental Sciences
Yang Yu, Chang Liu, Shaojia Gu, Yuhui Wei, Lei Li, Qing Qu
Summary: Upgrading and recycling spent catalysts into high-perform bio-catalysts can address palladium resource shortages and environmental problems. By using Escherichia coli as an electron transfer intermediate, the recovery efficiency of palladium exceeded 98.6%.
ENVIRONMENTAL POLLUTION
(2023)
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)