Article
Chemistry, Organic
Simon X. Lin, Jonathan Sperry
Summary: The synthesis of lysiformine, a bisindole alkaloid, was described. The heterocyclic framework of the natural product was assembled using iterative Suzuki coupling and reductive alkylation reactions starting from a pyridine derived from kojic acid. NMR spectroscopic analysis confirmed that the synthetic sample matched well with the natural product, highlighting the rarity of a marine natural product containing a 3-hydroxypyridine.
TETRAHEDRON LETTERS
(2023)
Article
Chemistry, Analytical
Shuzhen Peng, Yun Chang, Xingli Zeng, Rong Lai, Mujing Yang, Dandan Wang, Xiaoshun Zhou, Yong Shao
Summary: We successfully programmed polyadenine DNA into a parallel duplex assembly using a polyvalent-binding assembler called nitidine (NIT) at neutral pH. The molecule planarity of natural isoquinoline alkaloids (NIAs) was found to be a determining factor in this assembly process. We also developed a gold nanoparticles-based colorimetric method to screen NIT out of NIAs for constructing the polyadenine assembly. Our work will inspire further interest in developing switches and sensors based on polyadenine by concentrating NIT within the parallel assembly.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Multidisciplinary
Xu Gong, Juan Huang, Xiangrui Sun, Ziling Chen, Ming Yang
Summary: Illicium sesquiterpenes, a family of biologically active secondary metabolites, have been synthesized using a comprehensive biosynthetic pathway and a synthetic route to illisimonin A and merrilactone A.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Organic
Lidong Shan, Yunxiang Weng, Hongchen Li, Lin Min, Xinyan Wang, Yuefei Hu
Summary: A novel tandem synthesis of benzo[a]acridines is developed using N-aryl-2-propynamides and alkynes through a Tf2O-promoted intermolecular Bischler-Napieralski reaction and a TfOH-promoted intramolecular Friedel-Crafts reaction.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Lidong Shan, Hongchen Li, Weiping Zheng, Xingyong Wang, Xinyan Wang, Yuefei Hu
Summary: Direct evidence explaining why 2-propynamides have never been used as substrates in Tf2O-promoted electrophilic activations was obtained. Furthermore, a new method for the synthesis of structurally special 2,4-disubstituted quinolines was developed, allowing easy diversification of the substituent at position 2 of quinolines.
Article
Chemistry, Physical
Abida Naseem Malik, Aleksey Kuznetsov, Akbar Ali, Muhammad Ashfaq, Muhammad Nawaz Tahir, Abubakar Siddique
Summary: The structures of two Schiffbase zwitterions have been analyzed, revealing similarities in crystal system and space group, as well as intermolecular attractive forces. The density functional theory calculations showed that the optimized geometries matched well with the experimental structures. Compound 3a demonstrated higher stability and reactivity towards redox reactions compared to 3b.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Multidisciplinary
Jamal Houssaini, Mohammed Naciri Bennani, Said Arhzaf, Chadia Mounir, Marwa Alaqarbeh, Hammou Ahlafi, Abdellatif Amhoud
Summary: This research paper discusses the synthesis of jasminaldehyde using chitosan-modified layered double hydroxide composite catalysts under microwave irradiation. The CS-functionalized catalyst showed better catalytic performance compared to the naked MgAl-NO3 catalyst.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Jie Tang, Sara Toufouki, Alula Yohannes, Shun Yao
Summary: The green reduction of BBR to THB and DHB was achieved using IL-assisted and solvent-free synthetic technologies, with detailed investigation into the reactive behavior and mechanisms under related conditions. Additionally, a reaction in tablet form was successfully carried out for the first time, and the performances of ten Bronsted acidic ILs in three series, as well as four solid-phase reactive technologies, were comprehensively compared.
REACTION CHEMISTRY & ENGINEERING
(2021)
Article
Materials Science, Ceramics
Raman Mnatsakanyan, Artur Aghoyan, Davit Davtyan
Summary: Boron monoposphide (BP) has unique physical and chemical characteristics, making it suitable for various practical applications. However, the difficult synthesis of the single phase of boron monophosphide limits its usage. Additionally, existing methods for synthesizing nanoscale BP often require high temperatures and long synthesis durations. This paper presents a simple, energy-efficient, and straightforward microwave activation synthesis method, which successfully produces pure single-phase BP nanopowder with a narrow size distribution (70-90 nm) in a short synthesis time (10 min).
CERAMICS INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Shuai Ma, Yiwei Hu, Jianjiao Chen, Xiaojuan Wang, Chenxi Zhang, Qianqian Liu, Guodi Cai, Hong Wang, Jianwei Zheng, Qianqian Wang, Lin Zhong, Bin Yang, Shengning Zhou, Yonghong Liu, Fanghai Han, Junjian Wang, Junfeng Wang
Summary: A novel compound named arthpyrone M (Art-M) derived from marine fungus Arthrinium arundinis showed potential antitumor activity against gastric cancer (GC) by inhibiting cell proliferation, invasion, and migration. The mechanism was found to be through suppressing the mTORC1 pathway. Additionally, Art-M enhanced the sensitivity of GC cells to apatinib and showed better efficacy when used in combination.
CHEMICO-BIOLOGICAL INTERACTIONS
(2023)
Article
Biochemistry & Molecular Biology
Junya Mukomura, Hiroki Nonaka, Hiromasa Sato, Maho Kishimoto, Masayoshi Arai, Naoyuki Kotoku
Summary: This study synthesized and evaluated simplified analogs of marine sponge-derived alkaloid to discover novel anti-mycobacterial substances. The ring truncation effectively reduced cytotoxicity, and the N-(2-arylethyl)quinolin-3-amine skeleton was identified as a promising scaffold for anti-mycobacterial lead compounds.
Article
Materials Science, Ceramics
Marta Maria Gonzalez-Barrios, Marina Tabuyo-Martinez, Vanessa Cascos, Oscar Juan Dura, Jose Antonio Alonso, David Avila-Brande, Jesus Prado-Gonjal
Summary: The combination of microwaves with other classical synthetic methods provides a powerful tool for the preparation of metal oxides and metal chalcogenides. This approach allows for significant modification of reaction kinetics by reducing the processing time to minutes and minimizing energy consumption. Microwave chemistry routes have been used to produce potential thermoelectric compounds such as SnS1-xSex and Zn0.98M0.02O (M = Al, Ga) in just a few minutes. The microwave synthesis method also produces high-quality phases.
CERAMICS INTERNATIONAL
(2022)
Article
Chemistry, Multidisciplinary
Stephanie Link, Yuanzhe Zhang, Stefan Heuser
Summary: This work presents a convenient microwave-assisted method for the synthesis of oxazolopyridines from aminopyridinols and carboxylic acids in the presence of propylphosphonic anhydride (T3P), providing access to various regioisomeric oxazolopyridines bearing either aliphatic or aromatic substituents in the 2-position. The method generally achieves good yields ranging from 65% to 88%, with even a bulky tert-butyl substituted oxazolopyridine accessible in a surprisingly high 49% yield.
RESULTS IN CHEMISTRY
(2021)
Review
Chemistry, Multidisciplinary
Yu Gao, Yuzhi Liu, Donglei Zou
Summary: This article reviews the application of microwave irradiation in synthesis and catalytic oxidation, including microwave irradiation alone, microwave with catalysts, microwave-Fenton, microwave-peralcohol, microwave-photochemistry, microwave-electrochemistry, and microwave-sonochemistry. Engineering for upscaling microwave irradiation is also presented.
ENVIRONMENTAL CHEMISTRY LETTERS
(2023)
Article
Materials Science, Ceramics
Egor M. Kostyukhin, Alexander L. Kustov, Nikolay V. Evdokimenko, Andrey I. Bazlov, Leonid M. Kustov
Summary: Lanthanum orthoferrite powders were synthesized via one-step hydrothermal reactions under mild conditions using microwave irradiation, resulting in nanocrystalline LaFeO(3) with a higher yield and reduced crystallite and particle size. The catalyst formed under microwave conditions showed enhanced activity in the decomposition of nitrous oxide compared to the catalyst prepared by conventional heating.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2021)
Article
Chemistry, Medicinal
Valerie Toum, Julie Bolley, Yoann Lalatonne, Carole Barbey, Laurence Motte, Marc Lecouvey, Jacques Royer, Nathalie Dupont, Joelle Perard-Viret
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2015)
Article
Chemistry, Organic
Farouk Berhal, Sebastien Tardy, Joelle Perard-Viret, Jacques Royer
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2009)
Article
Chemistry, Organic
Delphine Halie, Joelle Perard-Viret, Sylvie Dufour, Jacques Royer
Article
Chemistry, Inorganic & Nuclear
Farouk Berhal, Joelle Perard-Viret, Jacques Royer
TETRAHEDRON-ASYMMETRY
(2010)
Article
Biochemical Research Methods
Imane Rihab Mami, Tabet Zatla Amina, Joelle Perard, Zoheir Arrar, Mohammed El Amine Dib
Summary: This study aimed to chemically modify Carlina oxide from Carthamus caeruleus and conduct in-silico study on its analogues. Five new compounds derived from Carlina oxide were synthesized and evaluated as potential inhibitors of bacterial enzymes. The results showed promising ligand interactions with the enzymes, with IM9 exhibiting the most favorable outcome.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
(2021)
Article
Chemistry, Organic
Imane Lazouni, Joelle Perard-Viret, Karim Hammad, Wassila Drici
Summary: In this paper, the synthesis of peptidomimetics containing oxazolidin-2-one and oxazolidine rings is reported. Two novel series of these heterocyclic peptidomimetics were obtained through an efficient intramolecular cyclization using serine as the starting material. In the case of oxazolidine, the formation of only one diastereoisomer was observed.
Article
Chemistry, Organic
Yoji Oderaotoshi, Hiroyuki Miyata, Satoshi Minakata, Mitsuo Komatsu
Article
Chemistry, Organic
S Turcaud, T Martens, E Sierecki, J Pérard-Viret, J Royer
TETRAHEDRON LETTERS
(2005)
Article
Chemistry, Inorganic & Nuclear
L Planas, J Pérard-Viret, J Royer
TETRAHEDRON-ASYMMETRY
(2004)
Article
Chemistry, Organic
L Planas, J Pérard-Viret, J Royer
JOURNAL OF ORGANIC CHEMISTRY
(2004)
Article
Chemistry, Organic
J Pérard-Viret, T Prangé, A Tomas, J Royer
Article
Chemistry, Organic
Isabelle Baussanne, Bruno Dudot, Joele Perard-Viret, Loic Planas, Jacques Royer
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)
