4.4 Article

Palladium-catalyzed aminocarbonylation of heteroaryl halides using di-tert-butylphosphinoferrocene

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 45, Pages 6126-6129

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.08.065

Keywords

Aminocarbonylation; Heteroaryls; Di-tert-butylphosphinoferrocene; Palladium

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Pd-catalyzed aminocarbonylation of heteroaryl halides, using monodentate ligand di-tert-butylphosphinoferrocene tetrafluoroborate is reported. Good to high yields were obtained with chiral amines on a variety of substrates including 2-bromo heteroaryls. (C) 2009 Elsevier Ltd. All rights reserved.

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