Journal
TETRAHEDRON LETTERS
Volume 50, Issue 28, Pages 4158-4160Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.04.131
Keywords
Pseudopeptide; Azapeptide; Mitsunobu; Exchange of protecting group
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Funding
- National Research Agency (ANR) [NT05_4_42848]
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The preparation of 2:1-[alpha/aza]-oligomer precursors is described via Mitsunobu and exchange of protecting groups protocols in four steps in good yields starting from N-tert-butyloxycarbonylaminophtalimide. Conformational studies showed that these building blocks further led to beta-turn-like folded 2:1-[alpha/aza]-trimer which suggests that they are good candidates to form foldamers. (C) 2009 Elsevier Ltd. All rights reserved.
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