Journal
TETRAHEDRON LETTERS
Volume 50, Issue 33, Pages 4762-4765Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.06.012
Keywords
3,4-Diarylpyrrole-2,5-dicarboxylates, Piloty-Robinson pyrrole synthesis; alpha-Diazo ester; Hydrazone; Polycitone; Storniamide
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Funding
- MEXT. HAITEKU (2008)
- Uehara Memorial Foundation (2008)
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We have developed a novel method for the synthesis of 3,4-diarylpyrrole-2,5-dicarboxylates via alpha-diazo esters, which are easily obtained from phenylalanine derivatives. Utilizing this method, intermediates of bioactive compounds having the structure of 3,4-diarylpyrrole-2,5-dicarboxylates were synthesized. (C) 2009 Elsevier Ltd. All rights reserved.
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