4.4 Article

Novel one-pot Cu-nanoparticles-catalyzed Mannich reaction

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 12, Pages 1355-1358

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.01.031

Keywords

Cu-nanoparticles; Mannich reaction; Recyclability; beta-Amino carbonyl compounds

Funding

  1. Dean, Research, University of Delhi
  2. Department of Science and Technology, Govt. of India

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Recyclable heterogeneous Cu-nanoparticles efficiently catalyzed the one-pot three-component Mannich reaction of ketones, aromatic aldehydes and amines in methanol. This method provides a novel and improved method for obtaining P-amino carbonyl compounds in terms of good yield with little catalyst loading. (c) 2009 Elsevier Ltd. All rights reserved.

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