4.4 Article

NbCl5 mediated deprotection of methoxy methyl ether

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 30, Pages 4318-4320

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.03.171

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Funding

  1. CSIR, New Delhi

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An efficient cleavage of methoxy methyl ether using NbCl5 is described. This protocol works efficiently with MOM ethers of alkyl, allyl, propargyl, benzyl alcohol and phenol derivatives. MOM esters are also found to be effectively cleaved under the present conditions. (C) 2009 Elsevier Ltd. All rights reserved.

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