Journal
TETRAHEDRON LETTERS
Volume 49, Issue 9, Pages 1450-1454Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.01.001
Keywords
ruthenium; ring-opening; epoxides; indoles
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Ruthenium-catalyzed regioselective ring-opening of aliphatic and aryl epoxides under solvent-free conditions is reported. It was found that RUCl3 center dot nH(2)O catalyzes the Friedel-Crafts alkylation of indoles, providing 3-alkylated derivatives in good yields under mild reaction conditions. (c) 2008 Elsevier Ltd. All rights reserved.
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