4.4 Article

Dithiocarbamate and CuO promoted one-pot synthesis of 2-(N-substituted)-aminobenzimidazoles and related heterocycles

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 6, Pages 992-995

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.12.022

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A rapid and efficient one-pot method for the synthesis of 2-(N-substituted)-aminobenzimidazoles is described, The reaction is promoted by dithiocarbamate and catalytic CuO. This procedure is general and can be applied to synthesize many potential drug candidates. (c) 2007 Elsevier Ltd. All rights reserved.

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