4.4 Article

Substituted azabicyclo[3.1.0]hexan-1-ols from aspartic and glutamic acid derivatives via titanium-mediated cyclopropanation

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 46, Pages 6512-6513

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.08.114

Keywords

Kulinkovich reaction; Cyclopropanol; Azabicycle

Funding

  1. NSF [CHEM-0515443]
  2. Wyeth Research
  3. University of Pennsylvania

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The Kulinkovich cyclopropanation reaction has been used to synthesize azabicyclo[3.1.0]hexanols from amino acid derivatives containing two ester moieties. (C) 2008 Elsevier Ltd. All rights reserved.

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