4.4 Article

Synthesis of indolylalkylphosphonates and 3-(1-diphenylphosphinoalkyl) indoles by reaction of 3-(1-arylsulfonlyalkyl) indoles with phosphorus derivatives

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 39, Pages 5645-5648

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.07.077

Keywords

conjugate addition; imines; indoles; phosphines; phosphites; sulfones

Funding

  1. University of Camerino

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Dialkyl phosphites as well as diphenylphosphine react with 3-(1-arylsulfonylalkyl) indoles under basic conditions leading to a formal substitution of the arylsulfonyl group through a reactive 3-alkylidene indole intermediate. (C) 2008 Elsevier Ltd. All rights reserved.

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