4.4 Article

Intramolecular thermal allenyne [2+2] cycloadditions: facile construction of the 5-6-4 ring core of sterpurene

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 2, Pages 376-378

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.11.042

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Funding

  1. NIGMS NIH HHS [R15 GM077179, R15 GM077179-01] Funding Source: Medline

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A variety of 1-allenyl-2-propargyl-substituted cyclopentanol derivatives were found to undergo facile intramolecular micro wave-assisted [2+2] allenyne cycloaddition reactions to generate tricyclic 5-6-4 ring systems present in the sterpurenes. (C) 2007 Elsevier Ltd. All rights reserved.

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