4.4 Article

A novel method for the synthesis of 3,4-disubstitutedpyrrole-2,5-dicarboxylates from hydrazones derived from α-diazo esters

Journal

TETRAHEDRON
Volume 69, Issue 21, Pages 4325-4330

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2013.03.037

Keywords

Pyrrole; Piloty-Robinson pyrrole synthesis; alpha-Diazo ester; Hydrazone

Funding

  1. Uehara Memorial Foundation

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Hydrazones obtained from alpha-diazo esters were converted to pyrroles when heated with thionyl chloride in alcohol. Among hydrazones, those substituted with a benzene ring on the beta-carbon to the ester are likely to give pyrroles in good yields. (C) 2013 Elsevier Ltd. All rights reserved.

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