Journal
TETRAHEDRON
Volume 68, Issue 44, Pages 9090-9094Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2012.08.054
Keywords
Cross-coupling; C-(aryl)-N-(amide) bond formation; Buchwald-Hartwig coupling; Domino reaction; Coupling-cyclization
Categories
Funding
- CSIR [01(2378)/10/EMR-II]
- DST, New Delhi
- CSIR, New Delhi
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Highly important trans-3,4-dihydro-2H-1,4-benzoxazine moieties were easily synthesized by domino aziridine ring opening with o-bromophenols and o-chlorophenols followed by the palladium catalyzed coupling-cyclization (intramolecular C-(aryl)-N-(amide) bond formation) with good to excellent yields. (C) 2012 Elsevier Ltd. All rights reserved.
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