Journal
TETRAHEDRON
Volume 66, Issue 6, Pages 1327-1334Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2009.12.011
Keywords
Click chemistry; Ferrocene amino acids; Ferrocene based chiral derivatives; Cycloaddition
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Funding
- CSIR, New Delhi
- DST New Delhi
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This work reports the synthesis of a wide range of ferrocenyl-amino acids and other derivatives in excellent yield Diverse amino acid containing azides were synthesized and ligated to ferrocene employing click reaction to access ferrocenyl amino acids Chiral alcohols, esters, diols, amines containing azido group were tagged to ferrocene via click reaction to generate ferrocene derived chiral derivatives A novel strategy for direct incorporation of ferrocene into a peptide and a new route to 1, 1'disubstituted feriocene amino acid derivative are reported (C) 2009 Elsevier Ltd All rights reserved
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