Article
Biochemistry & Molecular Biology
Chao Wang, Yuelin Li, Zi Liu, Zeyu Wang, Zihan Liu, Shuai Man, Yujing Zhang, Kai Bao, Yingliang Wu, Qi Guan, Daiying Zuo, Weige Zhang
Summary: A series of 1-aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols were designed, synthesized, and evaluated for anticancer activity, with compound 6-31 showing remarkable potency against various cancer cell lines. This study offers a new perspective for the development of antitumor agents targeting tubulin.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Dongsen Zheng, Jianzhong Wang, Yingxian Duo, Zhuqing Fang, Chuang Yu, Meizhuang Qiao, Jiping Liu
Summary: This paper focuses on the pyrolysis behavior of 5-amino-1 H-tetrazole (5AT) and investigates the catalytic effects of nitrocellulose (NC) and potassium nitrate (KNO3) on the thermal decomposition mechanism and kinetics behavior of 5AT. The results suggest that adding NC simplifies the degradation process of 5AT and KNO3 decreases the activation energy and changes the reaction model. These findings provide valuable guidance for improving the design of environmentally friendly pyrotechnics.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2022)
Article
Chemistry, Inorganic & Nuclear
Hanieh Gharoubi, Mahmoud Nasrollahzadeh, Zahra Khorsandi, Marcos A. L. Nobre, Sungkyun Choi, Benjamin Kruppke, Hossein Ali Khonakdar
Summary: A new catalyst based on Cu(II)-5-amino-1H-tetrazole complex immobilized on graphene oxide-modified magnetic nanoparticles has been synthesized. The catalyst showed high catalytic activity in the synthesis of N-benzyl-N-aryl-5-amino-1H-tetrazoles. It has excellent chemical stability and the potential for practical synthetic applications.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Organic
Masahiko Seki, Yusuke Takahashi
Summary: Highly convergent synthesis of angiotensin II receptor blockers has been achieved through late-stage C-H arylation using functionalized aryl bromides. Different reaction conditions were found to lead to distinct coupling products during the arylation reaction.
SYNTHESIS-STUTTGART
(2021)
Article
Chemistry, Organic
Amin Khoshnoud, Ali Reza Pourali, Hossein Behniafar
Summary: Tetrazoles have diverse applications, but current synthesis methods have drawbacks, leading to the search for alternatives like using nanoparticles to enhance reaction rates.
LETTERS IN ORGANIC CHEMISTRY
(2022)
Article
Energy & Fuels
Jiu Chen, Quan Liu, Xian-Zhao Song, Si-Yuan Zhou, Bin Li, Li-Feng Xie, Guang-Cheng Yang, Cheng-Yan Cao, Song Lu, Dan Zhang
Summary: This study investigates the thermal decomposition behavior of 5-Amino-1H-Tetrazole (5AT) and the catalytic effect of different catalysts on its pyrolysis. The results indicate that PbO catalyst exhibits the best catalytic effect. Furthermore, the likely pyrolysis route of 5AT is inferred through the analysis of evolved gas products.
Article
Energy & Fuels
Jiu Chen, Bin Li, Cheng-Yang Cao, Si-Yuan Zhou, Li-Feng Xie, Dan Zhang
Summary: This study investigates the pyrolysis behaviors of 5-Amino-1H-Tetrazole (5AT) and the effects of different modification methods on its combustion properties. The results show that boron powder and copper powder have different catalytic effects on the decomposition of 5AT at different stages. The solution recrystallization method exhibits better modification effect in the later stages, while copper powder shows a stronger catalytic effect compared to boron powder. These findings provide valuable guidance for the understanding and applications of 5AT-based propellants.
Article
Engineering, Chemical
Sara A. Mahdy, Soha A. Abdel-Gawad, Rabab M. El-Sherif, I. M. Ghayad
Summary: The performance of 5-phenyl-1H-tetrazole (PTAH) and 5-(4-pyridyl)-1H-tetrazole (PyTAH) as corrosion inhibitors on copper and commercial brass in simulated seawater containing 3.5% NaCl was investigated. The results showed that PTAH exhibited better corrosion inhibition efficiency with 97% for copper and approximately 96% for brass at an optimal concentration of 0.01 M. Surface investigations revealed that the presence of PTAH significantly protected the copper and brass surfaces. The Langmuir adsorption isotherm indicated physiochemical adsorption of the inhibitors on the sample surfaces, while the Arrhenius plot demonstrated an increase in corrosion reaction activation energy after the addition of the inhibitor, indicating its inhibitive effect on copper and brass surfaces.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Chemistry, Applied
Dongsen Zheng, Jianzhong Wang, Yinxian Duo, Jiping Liu
Summary: This paper investigates the catalytic effects of different types of oxidizers on 5-Amino-1H-tetrazole (5AT). The thermal behavior and activation energy of 5AT are analyzed using TG-DSC test and Kissinger/Ozawa methods. The experimental results show that 5AT-AN has the lowest activation energy and the degradation process is simplified into one step. The addition of AP, NaClO4, and MnO2 can promote the pyrolysis process of 5AT, while Cr2O3 mainly acts as a catalyst above 400 degrees C without oxidation. The catalytic mechanism of Cr2O3 mainly involves polyaddition and ring-opening reactions of N-containing heterocycles. These findings offer valuable guidance for understanding, designing, and using 5AT-based propellants.
PROPELLANTS EXPLOSIVES PYROTECHNICS
(2023)
Article
Energy & Fuels
Si -Yuan Zhou, Jiu Chen, Xuan Li, Fan Jia, Dan Zhang, Li-Feng Xie, Bin Li, Lin Jiang
Summary: This study investigates the effect of Cu elements on the pyrolysis performance of 5AT and compares Cu and CuO as catalysts. The results show that the catalysts mainly act on the third stage of 5AT pyrolysis, and Cu is more effective than CuO. The findings provide valuable reference for catalyst selection, compounding method, and further combustion process.
Article
Chemistry, Organic
Yulia Krivolapova, Olesya A. Tomashenko, Liya D. Funt, Dar'ya Spiridonova, Mikhail S. Novikov, Alexander F. Khlebnikov
Summary: Azirine-triazole hybrids were selectively synthesized under different reaction conditions and the reaction mechanism and selectivity were discussed based on DFT calculations.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Gangam Srikanth Kumar, Stefano Racioppi, Eva Zurek, Qing Lin
Summary: This article reports the design of a super fast bioorthogonal ligation reactant pair, enabling rapid bioorthogonal labeling on live cells.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Crystallography
Haolong Zhai, Xiaoping Cui, Yuping Gan
Summary: This study focuses on the combustion tear gas mixture and optimizes its formula by adding 5-amino-1H-tetrazole. The study characterizes the combustion parameters and smoke effects of the mixture and finds that adding an appropriate amount of 5-amino-1H-tetrazole can improve its combustion and smoking performance.
Article
Biochemistry & Molecular Biology
Alina Secrieru, Rabah Oumeddour, Maria L. S. Cristiano
Summary: This study investigates the fragmentation patterns of 5-allyloxy-1-aryl-tetrazoles and 4-allyl-1-aryl-tetrazolole-5-ones under electron impact mass spectrometry and correlates them with the UV-induced fragmentation channels of matrix-isolated tetrazole derivatives. The results show that the pathways of tetrazole fragmentation in EI-MS are influenced by electronic effects induced by substitutions, providing efficient tools for reactivity predictions. The identified fragments are consistent with previous investigations, showcasing a similarity in tetrazoles' behavior under EI-MS and UV-irradiation.
Article
Chemistry, Multidisciplinary
Guillaume Reynard, Julien Moisan-Labelle, Etienne Parent, Helene Lebel
Summary: This study describes a method for the synthesis of disubstituted tetrazoles from 1H-5-monosubstituted tetrazoles via the aliphatic amine diazotization reaction. The transient alkyl diazonium intermediate acts as an alkylating agent. Although the 2,5-disubstituted tetrazole is preferentially formed, the minor 1,5-disubstituted tetrazole can also be isolated in some cases. The regioselectivities are highly variable and cannot be solely attributed to steric hindrance.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Polymer Science
Tayebe Khanlari, Yadollah Bayat, Mohammad Bayat
Summary: This study aimed to improve the thermal and mechanical properties of PGN-based energetic polyurethane network by using a novel flexible chain triblock copolymer and different curing agents. The addition of BuNENA plasticizer showed better compatibility with the copolymer compared to other plasticizers. Polyurethane mixture with IPDI/N100 curing agents and 15 wt% BuNENA demonstrated appropriate mechanical properties.
Article
Chemistry, Multidisciplinary
Mohammad Dashteh, Saeed Baghery, Mohammad Ali Zolfigol, Ardeshir Khazaei, Sajjad Makhdoomi, Maliheh Safaiee, Jamshid Rakhtshah, Yadollah Bayat, Asiye Asgari
Summary: A novel catalyst was studied for the facile and benign syntheses of [1,2,4]triazolo [5,1-b]quinazolines and [1,2,4]triazolo [1,5-b]pyrimidines under solvent-free conditions, resulting in high yields and short reaction times. The catalyst was easily recovered and reused, and some of the obtained products were reported for the first time.
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
(2022)
Article
Polymer Science
Yadollah Bayat, Sahar Jodar, Tayebe Khanlari
Summary: In this research, a tri-block copolymer PCL-PB-PCL was synthesized and its potential application in the propellant industries as a binder was investigated. The thermal behavior and decomposition kinetics of the copolymer were studied. Polyurethane elastomers were also synthesized using the copolymer and reactants with different NCO/OH ratios. The effect of a chain extender on the mechanical properties of the polyurethane-based copolymer was examined.
JOURNAL OF POLYMER RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Yasamin Ajdari, Ali Reza Faraji, Fatemeh Ashouri
Summary: This study aims to develop an efficient and environmentally sustainable biocatalyst for the synthesis of vitamin K3. Novel Co NPs impregnated pectin-gelatin and grafted pectin-gelatin modified magnetic beads were designed and fabricated. The green synthesis method showed advantages such as the heterogeneous nature of catalysts, environmentally-friendly conditions, high activity, and sustainable performance of the biocatalyst.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Mohammad Ali Zarei, Yadollah Bayat, Ghasem Oskueyan
Summary: In this research, a prepolymer from a blend of HTPB and PEG was prepared and used for synthesizing PU elastomer with glycerol. The compatibility of n-BuNENA as a plasticizer with non-energetic PU matrices was investigated. The results showed that the incorporation of PEG improved the compatibility of the plasticizer with PU, but reduced the thermal stability. Addition of PEG increased the modulus and tensile strength, while addition of plasticizer decreased the modulus but enhanced the tensile strength and elongation.
JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY
(2022)
Article
Polymer Science
Fahimeh Ghoroghchian, Yadollah Bayat, Fatemeh Abrishami
Summary: Polyurethane elastomers of PPG-GAP-PPG triblock were copolymer prepared for the first time in this work, achieving improved mechanical properties through curing the synthesized binder using isocyanates such as IPDI, TDI, and N-100, as well as their mixtures. Incorporation of a more compatible plasticizer, such as 5% BuNENA, resulted in the best mechanical properties, while optimized curing results were obtained using equal weights of IPDI/N100 curing agents and DBTDL as a catalyst. Mechanical properties were characterized through elongation tests, showing significant improvements in both elongation at break and tensile strength. Thermal properties were studied using DMTA and DSC techniques.
JOURNAL OF POLYMER RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Nahale Kakavand, Mohammad Bayat, Yadollah Bayat
Summary: A one-pot three component reaction in ethanol for the synthesis of acenaphthoindolopyrimidine derivatives has been reported. The method is facile and has benefits such as readily available starting materials and environmentally friendly conditions.
MOLECULAR DIVERSITY
(2023)
Article
Chemistry, Physical
Leyla Nazemi Nasirmahale, Farhad Shirini, Yadollah Bayat, Masoumeh Mazloumi
Summary: In this article, a new efficient nano-catalyst, TiO2-[bip]-NH2+ C(NO2)(3)(-), was used to promote the synthesis of imidazo[1,2a]pyrimidine-3-carbonitriles and 1,2,4-triazolo[4,3-a]pyrimidines derivatives via a three-component one-pot condensation. The products were obtained under mild and solvent-free conditions and identified by comparing their physical properties and spectral data with authentic samples. The prepared catalyst was characterized using various analytical techniques. This method offers short reaction times, high product yields, easy separation of products, and recyclability of the catalyst.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Sara Movahedian, Ali Reza Faraji, Fatemeh Ashouri
Summary: A magnetic-chitosan/amine-supported CuNP composite was fabricated and proven to be an efficient biocomposite for the degradation of HEPES as a biological pollutant and for selective allylic oxidation of cyclohexene. The dispersion of Cu NPs and the catalytic performance of the activator were promoted by the appropriate nature and particle size of the self-cross-linked amine-aldehyde-chitosan matrix. The composite showed high removal efficiency and pseudo-first order kinetics in wide pH ranges.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Applied
Yadollah Bayat, Ghazaleh Taheripouya, Vida Zeynali, Vahid Azizkhani
Summary: In recent years, hollow cage-type molecular structures have attracted scientific attention due to their unique properties. One of these compounds, CL-20, is a polycyclic nitramine with a cage structure. It has high density and high heat of formation. It also has multiple polymorphs and is more powerful than HMX. CL-20 has various military and commercial applications.
JOURNAL OF ENERGETIC MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Milad Alizadeh, Yadollah Bayat
Summary: In this study, novel glycidyl nitrate copolymers (GNCOPs) and meta-substituted derivatives were proposed as propulsion materials. Chemical reactivity indices were calculated using density functional theory (DFT) method to predict their behavior in burning process. The results showed that adding functional groups changed the reactivity of GNCOP compounds and they exhibited dual properties in interaction with oxygen molecule. Optoelectronic study revealed three significant excitations. Adding functional groups into GNCOPs can introduce new materials with high energetic properties.
JOURNAL OF MOLECULAR MODELING
(2023)
Article
Polymer Science
Ghasem Oskueyan, Yadollah Bayat, Masoud Mostafavi, Tayebe Khanlari
Summary: A triblock copolymer of polypropylene glycol-polytetrahydrofuran-polypropylene glycol (TPPG) with a molecular weight of 2330 g mol(-1) was synthesized using polytetrahydrofuran as a macroinitiator via ring-opening polymerization of propylene oxide. The characterization of the product was done using H-1 and C-13-NMR spectroscopy, FT-IR, and gel permeation chromatography (GPC). The thermal behavior of the copolymer was investigated by differential scanning calorimetry (DSC). Optimum synthesis conditions were determined with BF3 center dot OEt2 as a catalyst, dichloromethane as a solvent, reaction time of 20 h, and temperature range of 0-5 degrees C. Copolyurethane elastomers were prepared using different NCO/OH ratios and showed excellent mechanical properties.
Article
Chemistry, Multidisciplinary
Behzad Bornas, Ali Reza Faraji, Fatemeh Ashouri
Summary: Due to the emerging demand for sustainable and cost-effective materials in catalytic systems, biopolymers derived from natural sources have been developed as promising alternatives to expensive and limited state-of-the-art materials. In this study, a new super magnetization bio-composite (MIOSC-N-et-NH2@CS-Mn) was designed and fabricated for advanced oxidative processes. The performance and characteristics of the magnetic bio-composite were thoroughly evaluated, and it showed high efficiency in degrading methylene orange and oxidizing ethylbenzene. Furthermore, the catalyst exhibited great stability, high recovery efficiency, and low metal leaching, making it suitable for water purification and selective aerobic oxidation of organic compounds.
Article
Chemistry, Multidisciplinary
Leyla Nazemi Nasirmahale, Farhad Shirini, Yadollah Bayat, Masoumeh Mazloumi
Summary: A novel reagent TiO2-[bip]-NH2+ C(NO2)(3)(-) was successfully synthesized and characterized. The reagent was used as a highly efficient and reusable nanocatalyst in the synthesis of hexahydroquinoline and 1,8-dioxo-decahydroacridine derivatives, with very short reaction times and excellent yields.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Applied
Yadollah Bayat, Fatemeh Jozi, Tayebe Khanlari
Summary: In this research, novel energetic plasticizers were synthesized via end-group modification of poly glycidyl nitrate. Thermal analysis showed that TNPGN has potential as a novel energetic plasticizer for propellant.
JOURNAL OF ENERGETIC MATERIALS
(2022)
Article
Chemistry, Organic
Fuying Zhu, Yamei Lin
Summary: In this study, a low-metal iron-supported catalyst (Fe20/NC-Mg) was reported for the efficient synthesis of quinoxaline compounds, using water as a solvent and without additional bases. The synergistic effect of FeNx site and Mg (OH)2 nanorods in the catalyst played a key role in achieving high yields (82-91%) in 16 examples. The gram-level synthesis and reusability of the catalysts after four cycles demonstrated its industrial application potential.
Article
Chemistry, Organic
Mikhail Kozlov, Alexey Tyurin, Andrey Dmitrenok, Vyacheslav Rusak, Aleksander Fedorov, Igor Zavarzin, Yulia Volkova
Summary: This study presents a novel and practical synthesis method for phosphorus-substituted 1,3,4-thiadiazolines using phosphorylthioformic acid hydrazides and ketones. The protocol demonstrates operational simplicity, availability of reagents, and tolerance towards different functional groups.
Article
Chemistry, Organic
Jisna Jose, Thomas Mathew
Summary: 2-Cyclopentenone and its derivatives are highly esteemed synthetic intermediates with exceptional utility in organic synthesis. They are favored structural motifs in numerous pharmaceutical drugs and natural products, highlighting their significance. The review discusses the various methods used to synthesize cyclopentenones from 2016 to 2023.
