Journal
TETRAHEDRON
Volume 66, Issue 34, Pages 6826-6831Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.06.048
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Funding
- Center for Bioactive Molecular Hybrids, Yonsei University
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Full details of studies directed toward the total synthesis of both enantiomers of rodgersinol are described. The key parts of our synthetic route to rodgersinol included the Cu(II)-mediated coupling of an arylboronic acid with an ortho-alkyl substituted phenol and regio- and stereoselective construction of the hydroxypropyl substituent. which avoided tedious protection/deprotection sequence. (C) 2010 Elsevier Ltd. All rights reserved.
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