Journal
TETRAHEDRON
Volume 66, Issue 33, Pages 6508-6513Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2010.04.098
Keywords
Asymmetric synthesis; Catalytic hydrogenation; Natural products; Antibiotics; Polycyclic compounds
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A short enantioselective and protecting group free access to the novel antibiotic platensimycin is reported. The crucial stereogenic information is provided by iridium catalyzed asymmetric hydrogenation. (C) 2010 Elsevier Ltd. All rights reserved.
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