Article
Chemistry, Multidisciplinary
Tyler J. Finnegan, Vageesha W. Liyana Gunawardana, Jovica D. Badjic
Summary: This review explores the potential role of abiotic hosts in sequestering and neutralizing organophosphorus toxins, highlighting molecular hosts that have shown binding and deactivation capabilities, along with strategies for their design. The authors hope to inspire others to create novel tools to combat the threat of organophosphorus compounds.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Review
Chemistry, Multidisciplinary
Tyler J. Finnegan, Vageesha W. Liyana Gunawardana, Jovica D. Badjic
Summary: Nerve agents are powerful organic compounds developed in the last century to inhibit acetylcholinesterase irreversibly. Exposure to these toxins can lead to a range of symptoms, with existing antidotes providing limited protection. While new prophylactics are being developed, there is a need for therapeutics capable of both preventing and reversing the effects of nerve agent poisoning for large-scale application.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Radoslav Z. Pavlovic, Remy F. Lalisse, Alexandar L. Hansen, Christopher A. Waudby, Zhiquan Lei, Murat Guney, Xiuze Wang, Christopher M. Hadad, Jovica D. Badjic
Summary: The molecular recognition processes of induced fit (IF) and conformational selection (CS) have been shown to play a central role in allosteric regulation in natural systems, where the substrate can either instruct the host to change its shape or the guest can select the optimal fit. A study demonstrated the potential interplay between the two mechanisms, providing insights for designing novel allosteric sequestering agents and chemosensors.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Inorganic & Nuclear
Wenyao Zhang, Jie Zhao, Dong Yang, Boyang Li, Yang Feng, Yue Wang, Xiaoyan Zheng, Xiao-Juan Yang, Biao Wu
Summary: This study presents the chiral induction and memory effect in an anion-coordination-driven tetrahedral cage. The induced chirality can be retained for a certain period even after replacing the chiral guests with achiral ones. The retention time of induced chirality can be controlled by using different achiral guests.
INORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Inorganic & Nuclear
Guotao Wang, Qixia Bai, Hui Liu, Zhengguang Li, Zhiyuan Jiang, Zhe Zhang, Yiming Li, Pingshan Wang
Summary: We achieved the adjustable self-assembly of metallosupramolecular cages by utilizing the steric hindrance effect, which allows for the precise control of their shape and size.
INORGANIC CHEMISTRY
(2023)
Review
Polymer Science
Peng Sun, Bo Qin, Jiang-Fei Xu, Xi Zhang
Summary: Supramolecular polymerization and supramolecular polymeric materials have gained significant attention in the past three decades. The concept of supramonomer, as a building block for noncovalent interactions leading to polymerization, has enabled the construction of various materials with controllable properties. This trend article highlights the recent progress in controllable polymerization and renewable materials based on supramonomers.
PROGRESS IN POLYMER SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Kentaro Harada, Ryo Sekiya, Takeharu Haino
Summary: By utilizing a confined space, we have achieved the formation of trimeric structures composed of acetic acid and tartaric acid derivatives, with transfer and enrichment of chirality. The generated capsule guides the dynamic axial chirality and enables the emission of circularly polarized luminescence in the NIR region.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Courtney Ngai, Hoi-Ting Wu, Bryce Camara, Christopher G. Williams, Leonard J. Mueller, Ryan R. Julian, Richard J. Hooley
Summary: A self-assembled cage structure was synthesized by controlling the self-assembly of internal amines. Despite carrying a positive charge, the structure can extract protons from water in solution. The internal amines have lower basicity compared to their counterparts in free solution. This moderation is a hallmark of enzymatic catalysis.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Hendrik V. Schroder, Michael Stadlmeier, Martin Wuhr, A. James Link
Summary: The lasso peptide benenodin-1 undergoes a reversible zip tie-like motion under heat activation, in which a peptidic wheel stepwise translates along a molecular thread. The equilibrium distribution is controlled by mechanical and non-covalent forces within the lasso peptide, with major restructuring of the intramolecular hydrogen bonding network affecting the peptide's physico-chemical properties.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Hendrik V. Schroder, Michael Stadlmeier, Martin Wuhr, A. James Link
Summary: The lasso peptide benenodin-1 undergoes a reversible zip tie-like motion under heat activation, with equilibrium distribution controlled by mechanical and non-covalent forces, major restructuring of the intramolecular hydrogen bonding network between wheel and thread affecting the peptide's physico-chemical properties.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Faustine d'Orchymont, Jason P. Holland
Summary: This article describes a rotaxane-based approach to synthesizing radiolabeled proteins and peptides for molecular imaging of cancer biomarkers in vivo. The technology provides a platform to explore how mechanical bonding can improve drug delivery, enhance tumor specificity, control radiotracer pharmacokinetics, and reduce dosimetry.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Li Shao, Hanwen Zhang, Xiaoqing He, Bin Hua, Xiangquan Hu, Caixia Wan, Steven P. Kelley, Jerry L. Atwood
Summary: A novel host-guest recognition motif based on PgC(3) and PEG was reported, which can selectively entrap high molecular weight PEG to form complex structures, and PgC(3) has the ability to efficiently adsorb PEG from aqueous solutions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Inorganic & Nuclear
Xiaoqin Cui, Fu-Qiang Zhang, Xin Li, Juan-Juan Hou, Huan Li, Xian-Ming Zhang
Summary: The research describes a new type of inorganic host material, titanium-oxide or polyoxotitanate clusters, which can encapsulate inorganic molecules or ions. A specific molecular cage, Ti-18, was found to encapsulate an entire organic ethylenediamine ion and demonstrate exceptional versatility in balancing charges and facilitating reactions. Ti-18 exhibits strong light absorption due to ethylenediamine coordination and shows superior photocatalytic activity compared to anatase TiO2.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
B. Hua, L. O. Alimi, G. Zhang, Y. Ding, B. Moosa, W. S. Baslyman, N. M. Khashab
Summary: This study investigates the use of methylene-bridged trianglamines as supramolecular adsorbents for the selective separation of linear alkane isomers. The selectivity is attributed to the host-guest complexation resulting from the size matching between the trianglamines cavity and the linear guest molecules. Moreover, the supramolecular adsorbents exhibit high recyclability and almost no loss of efficiency, showing great promise for industrial applications.
MATERIALS TODAY CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Chiara F. M. Mirabella, Gemma Aragay, Pablo Ballester
Summary: We report the self-assembly of shape-persistent [1 + 1] tetra-imine cages 1 based on two different tetra-alpha aryl-extended calix[4]pyrrole scaffolds in chlorinated solvents and in a 9 : 1 CDCl3 : CD3CN solvent mixture. The use of a bis-N-oxide 4 as template has a positive effect on the reaction yield. The binding properties of the self-assembled tetra-imine cages 1 with pyridine N-oxide derivatives were investigated using H-1 NMR spectroscopy.
Article
Chemistry, Multidisciplinary
M. R. Ranga Prabhath, Julia Romanova, Richard J. Curry, S. Ravi P. Silva, Peter D. Jarowski
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2015)
Article
Chemistry, Physical
Julia Romanova, M. R. Ranga Prabhath, Peter D. Jarowski
JOURNAL OF PHYSICAL CHEMISTRY C
(2016)
Article
Chemistry, Multidisciplinary
Yirong Mo, Huaiyu Zhang, Peifeng Su, Peter D. Jarowski, Wei Wu
Article
Chemistry, Physical
Julia Romanova, Yousif Sadik, M. R. Ranga Prabhath, J. David Carey, Peter D. Jarowski
JOURNAL OF PHYSICAL CHEMISTRY C
(2017)
Article
Chemistry, Multidisciplinary
G. Dinesha M. R. Dabera, K. D. G. Imalka Jayawardena, M. R. Ranga Prabhath, Iskandar Yahya, Y. Yuan Tan, N. Aamina Nismy, Hidetsugu Shiozawa, Markus Sauer, G. Ruiz-Soria, Paola Ayala, Vlad Stolojan, A. A. Damitha T. Adikaari, Peter D. Jarowski, Thomas Pichler, S. Ravi P. Silva
Article
Chemistry, Multidisciplinary
Milan Kivala, Corinne Boudon, Jean-Paul Gisselbrecht, Barbara Enko, Paul Seiler, Imke B. Mueller, Nicolle Langer, Peter D. Jarowski, Georg Gescheidt, Francois Diederich
CHEMISTRY-A EUROPEAN JOURNAL
(2009)
Article
Chemistry, Multidisciplinary
Yi-Lin Wu, Filip Bures, Peter D. Jarowski, W. Bernd Schweizer, Corinne Boudon, Jean-Paul Gisselbrecht, Francois Diederich
CHEMISTRY-A EUROPEAN JOURNAL
(2010)
Article
Chemistry, Multidisciplinary
Anna K. H. Hirsch, Philippe Reutenauer, Marc Le Moignan, Sebastien Ulrich, Peter J. Boul, Jack M. Harrowfield, Peter D. Jarowski, Jean-Marie Lehn
CHEMISTRY-A EUROPEAN JOURNAL
(2014)
Article
Chemistry, Multidisciplinary
Peter D. Jarowski, Yirong Mo
CHEMISTRY-A EUROPEAN JOURNAL
(2014)
Article
Chemistry, Multidisciplinary
Yi-Lin Wu, Francesca Tancini, W. Bernd Schweizer, Daniela Paunescu, Corinne Boudon, Jean-Paul Gisselbrecht, Peter D. Jarowski, Enrico Dalcanale, Francois Diederich
CHEMISTRY-AN ASIAN JOURNAL
(2012)
Article
Chemistry, Organic
Brian B. Frank, Philip R. Laporta, Benjamin Breiten, Mark C. Kuzyk, Peter D. Jarowski, W. Bernd Schweizer, Paul Seiler, Ivan Biaggio, Corinne Boudon, Jean-Paul Gisselbrecht, Francois Diederich
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2011)
Article
Chemistry, Organic
Francesca Tancini, Yi-Lin Wu, W. Bernd Schweizer, Jean-Paul Gisselbrecht, Corinne Boudon, Peter D. Jarowski, Marten T. Beels, Ivan Biaggio, Francois Diederich
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2012)
Article
Chemistry, Multidisciplinary
Mohammad R. Alenezi, Abdullah S. Alshammari, Talal H. Alzanki, Peter Jarowski, Simon John Henley, S. Ravi P. Silva
Article
Chemistry, Organic
Peter D. Jarowski, Yi-Lin Wu, Corinne Boudon, Jean-Paul Gisselbrecht, Maurice Gross, W. Bernd Schweizer, Francois Diederich
ORGANIC & BIOMOLECULAR CHEMISTRY
(2009)
Article
Chemistry, Multidisciplinary
Benjamin Breiten, Yi-Lin Wu, Peter D. Jarowski, Jean-Paul Gisselbrecht, Corinne Boudon, Markus Griesser, Christine Onitsch, Georg Gescheidt, W. Bernd Schweizer, Nicolle Langer, Christian Lennartz, Francois Diederich
Article
Chemistry, Organic
Fuying Zhu, Yamei Lin
Summary: In this study, a low-metal iron-supported catalyst (Fe20/NC-Mg) was reported for the efficient synthesis of quinoxaline compounds, using water as a solvent and without additional bases. The synergistic effect of FeNx site and Mg (OH)2 nanorods in the catalyst played a key role in achieving high yields (82-91%) in 16 examples. The gram-level synthesis and reusability of the catalysts after four cycles demonstrated its industrial application potential.
Article
Chemistry, Organic
Mikhail Kozlov, Alexey Tyurin, Andrey Dmitrenok, Vyacheslav Rusak, Aleksander Fedorov, Igor Zavarzin, Yulia Volkova
Summary: This study presents a novel and practical synthesis method for phosphorus-substituted 1,3,4-thiadiazolines using phosphorylthioformic acid hydrazides and ketones. The protocol demonstrates operational simplicity, availability of reagents, and tolerance towards different functional groups.
Article
Chemistry, Organic
Jisna Jose, Thomas Mathew
Summary: 2-Cyclopentenone and its derivatives are highly esteemed synthetic intermediates with exceptional utility in organic synthesis. They are favored structural motifs in numerous pharmaceutical drugs and natural products, highlighting their significance. The review discusses the various methods used to synthesize cyclopentenones from 2016 to 2023.