Curcumin and lung cancer—a review

Apigenin shows synergistic anticancer activity with curcumin by binding at different sites of tubulin

(2013) Diptiman Choudhury et al.   BIOCHIMIE

A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin®) in cancer patients

(2013) Masashi Kanai et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Curcumin–cyclodextrin complexes potentiate gemcitabine effects in an orthotopic mouse model of lung cancer

(2012) N Rocks et al.   BRITISH JOURNAL OF CANCER

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

T63, a new 4-arylidene curcumin analogue, induces cell cycle arrest and apoptosis through activation of the reactive oxygen species–FOXO3a pathway in lung cancer cells

(2012) Hao Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Curcumin mediated epigenetic modulation inhibits TREM-1 expression in response to lipopolysaccharide

(2012) Zhihong Yuan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Role of TGF-β signaling in curcumin-mediated inhibition of tumorigenicity of human lung cancer cells

(2012) Raktima Datta et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Curcumin inhibits tumor proliferation induced by neutrophil elastase through the upregulation of α1-antitrypsin in lung cancer

(2012) Yan Xu et al.   Molecular Oncology

Curcumin Blocks Small Cell Lung Cancer Cells Migration, Invasion, Angiogenesis, Cell Cycle and Neoplasia through Janus Kinase-STAT3 Signalling Pathway

(2012) Cheng-Liang Yang et al.   PLoS One

Premature Mitochondrial Senescence and Related Ultrastructural Changes during Lung Carcinogenesis Modulation by Curcumin and Resveratrol

(2012) Anshoo Malhotra et al.   ULTRASTRUCTURAL PATHOLOGY

Synergistic antitumor efficiency of docetaxel and curcumin against lung cancer

(2011) H. Yin et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Enhancement of Mitomycin C-Induced Cytotoxicity by Curcumin Results from Down-Regulation of MKK1/2-ERK1/2-Mediated Thymidine Phosphorylase Expression

(2011) Shao-Hsing Weng et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

How do real tumors become resistant to cisplatin?

(2011) Piet Borst et al.   CELL CYCLE

Curcumin Induces Small Cell Lung Cancer NCI-H446 Cell Apoptosis via the Reactive Oxygen Species-Mediated Mitochondrial Pathway and Not the Cell Death Receptor Pathway

(2011) Cheng-Liang Yang et al.   DNA AND CELL BIOLOGY

Curcumin

(2011) Mark G. Alexandrow et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Low-dose curcumin leads to the inhibition of tumor growth via enhancing CTL-mediated antitumor immunity

(2011) Feifei Luo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

2011 Focused Update of 2009 American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non–Small-Cell Lung Cancer

(2011) Christopher G. Azzoli et al.   JOURNAL OF CLINICAL ONCOLOGY

Lysosomal membrane permeabilization is involved in curcumin-induced apoptosis of A549 lung carcinoma cells

(2011) Qing-Yong Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Curcumin reduces pulmonary tumorigenesis in vascular endothelial growth factor (VEGF)-overexpressing transgenic mice

(2011) Yu-Tang Tung et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Synergistic Effect of Curcumin and Cisplatin via Down-Regulation of Thymidine Phosphorylase and Excision Repair Cross-Complementary 1 (ERCC1)

(2011) M.-S. Tsai et al.   MOLECULAR PHARMACOLOGY

Curcumin Induces EGFR Degradation in Lung Adenocarcinoma and Modulates p38 Activation in Intestine: The Versatile Adjuvant for Gefitinib Therapy

(2011) Jen-Yi Lee et al.   PLoS One

Curcumin enhances the mitomycin C-induced cytotoxicity via downregulation of MKK1/2–ERK1/2-mediated Rad51 expression in non-small cell lung cancer cells

(2011) Jen-Chung Ko et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Curcumin sensitizes non-small cell lung cancer cell anoikis through reactive oxygen species-mediated Bcl-2 downregulation

(2010) Varisa Pongrakhananon et al.   APOPTOSIS

Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway

(2010) Jian Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Apoptosis of Human Lung Cancer Cells by Curcumin Mediated through Up-Regulation of “Growth Arrest and DNA Damage Inducible Genes 45 and 153”

(2010) Achinto Saha et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R)

(2010) Tijana Andjelkovic et al.   CANCER BIOLOGY & THERAPY

A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer

(2010) Masashi Kanai et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Curcumin, the Golden Spice From Indian Saffron, Is a Chemosensitizer and Radiosensitizer for Tumors and Chemoprotector and Radioprotector for Normal Organs

(2010) Ajay Goel et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Dietary Curcumin Increases Antioxidant Defenses in Lung, Ameliorates Radiation-Induced Pulmonary Fibrosis, and Improves Survival in Mice

(2010) James C. Lee et al.   RADIATION RESEARCH

Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively?

(2009) Jayaraj Ravindran et al.   AAPS Journal

Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF)

(2009) Song-Shei Lin et al.   CANCER LETTERS

Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice

(2009) S.J. Moghaddam et al.   CARCINOGENESIS

Curcumin as an Anti-Cancer Agent: Review of the Gap Between Basic and Clinical Applications

(2009) G. Bar-Sela et al.   CURRENT MEDICINAL CHEMISTRY

Long-Term Results of the International Adjuvant Lung Cancer Trial Evaluating Adjuvant Cisplatin-Based Chemotherapy in Resected Lung Cancer

(2009) Rodrigo Arriagada et al.   JOURNAL OF CLINICAL ONCOLOGY

Curcumin modulates eukaryotic initiation factors in human lung adenocarcinoma epithelial cells

(2009) Lixia Chen et al.   MOLECULAR BIOLOGY REPORTS

Cytoskeleton Disorganization during Apoptosis Induced by Curcumin in A549 Lung Adenocarcinoma Cells

(2009) Qingyong Chen et al.   PLANTA MEDICA

DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway

(2008) Song-Shei Lin et al.   CANCER LETTERS

Curcumin Inhibits Lung Cancer Cell Invasion and Metastasis through the Tumor Suppressor HLJ1

(2008) H.-W. Chen et al.   CANCER RESEARCH

Pharmaceutical Management of Ovarian Cancer

(2008) Maurie Markman   DRUGS

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

(2008) Bharat B. Aggarwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

TREM-1 Expression in Tumor-associated Macrophages and Clinical Outcome in Lung Cancer

(2007) Chao-Chi Ho et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE