Article
Environmental Sciences
Adrian R. Muxworthy, Claire Lam, David Green, Alison Cowan, Barbara A. Maher, Tomasz Gonet
Summary: The study used magnetic analysis on inhalable particulate matter collected from different monitoring stations in London to identify high concentrations of magnetite particles and the presence of nanoparticles at low temperatures. Vehicle emissions were confirmed as the main source of pollutants, with meteorological events affecting the removal of larger airborne particles.
ATMOSPHERIC ENVIRONMENT
(2022)
Article
Engineering, Electrical & Electronic
Songfei Su, Jinyan Chen, Pengzhan Liu, Mengxin Sun, Huanbo Cheng
Summary: This study presents a method for trapping and collecting airborne particulate matter using an ultrasonic device system, which has been validated through numerical simulations and experiments and investigated the impact of various parameters on collection performance. Due to its contactless and mild handling attributes, this ultrasonic airborne particulate matter sampler can avoid clogging and secondary pollution issues compared to other methods.
JOURNAL OF MICROMECHANICS AND MICROENGINEERING
(2021)
Article
Environmental Sciences
Tomasz Gonet, Barbara A. Maher, Jana Kukutschova
Summary: The study found that vehicle brake wear is the main source of airborne magnetite in the roadside environment in the UK, accounting for 68%-85%. In comparison, diesel and petrol engine emissions account for 7%-12% and 2%-4% respectively, while background dust contributes around 6%-10%. The high magnetite content in vehicle brake wear may pose potential risks to human cardiovascular and neurological health.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Pharmacology & Pharmacy
Kexin Shi, Qichuan Yin, Xiajing Tang, Xiaoning Yu, Sifan Zheng, Xingchao Shentu
Summary: This study explores the role of necroptosis in ocular surface injury caused by airborne particulate matter (PM). It was found that PM exposure may trigger cell damage through necroptosis, and the specific inhibitor Necrostatin-1 (Nec-1) reduces PM-induced cell damage and inflammation. The findings suggest that Nec-1 could be a novel therapeutic target for ocular surface disorders, particularly dry eye disease exacerbated by airborne PM pollution.
Article
Environmental Sciences
M. Kermenidou, Ll Balcells, C. Martinez-Boubeta, A. Chatziavramidis, I Konstantinidis, T. Samaras, D. Sarigiannis, K. Simeonidis
Summary: This research established a novel method of collecting quantitative data on combustion-emitted particulate matter through magnetic characterization and analysis, demonstrating varying levels of magnetically-responding particles in urban and suburban areas of Thessaloniki, Greece. The study found that Fe3O4 and similar ferrites, some of which attached to heavy metals, are the dominant magnetic contributors from anthropogenic high-temperature processes such as traffic emissions. Nasal cytologic samples collected from residents showed consistent magnetic behavior, confirming the critical role of nanosized magnetic particles in assessing air pollution threats.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Liangliang Niu, Liping Li, Chao Xing, Bin Luo, Chunchun Hu, Maomao Song, Jingping Niu, Ye Ruan, Xinghuai Sun, Yuan Lei
Summary: Studies have shown that PM2.5 exposure can induce corneal toxicity through triggering cell pyroptosis, providing novel evidence in this study.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Agricultural Engineering
Yingjie Yang, Shelley P. Kirychuk, Yuchen Si, Myra C. Martel, Huiqing Guo, Bernardo Z. Predicala, Lifeng Zhang
Summary: Animal buildings are a significant contributor to particulate matter pollution, but a laboratory-scale electrospray system has been developed to generate highly-charged nano sized water droplets called engineered water nanostructures (EWNS), which have shown effectiveness in reducing livestock particulate matter. The study found that negative voltages generated higher numbers of EWNS, and the water consumption of the developed electrospray was relatively low compared to other methods, achieving reduction efficiencies comparable to wet electrostatic scrubbers.
BIOSYSTEMS ENGINEERING
(2022)
Article
Environmental Sciences
Jihwan Kim, Jeongju Kim, Youngdo Kim, Taesik Go, Sang Joon Lee
Summary: Phytoremediation is an eco-friendly technique to reduce hazardous particulate matter in the air. This study proposes a novel methodology using digital in-line holographic microscopy to compare the electrostatic interactions between PMs and plant leaves, and quantitatively evaluate the settling velocity of PMs on different plant leaves. The findings show that the curved microstructures of hairy trichomes enhance the electric field intensity near trichomes, thus increasing the ability of plant leaves to capture PMs.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Environmental Sciences
Qin Li, Danni Zheng, Yuanyuan Wang, Rong Li, Hongping Wu, Suxin Xu, Yuefan Kang, Yunxia Cao, Xiujuan Chen, Yimin Zhu, Shuguang Xu, Zi-Jiang Chen, Ping Liu, Jie Qiao
Summary: The study revealed a relationship between PM2.5 exposure and reduced human fecundity, as evidenced by longer time to pregnancy and increased odds of infertility.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Alireza Mahdavi, Justin Dingle, Arthur W. H. Chan, Jeffrey A. Siegel
Summary: Filters in HVAC systems can serve as air-cleaning and sampling devices, but may not always effectively remove particles and trace metals due to other dominant source and loss mechanisms. While QFF shows promise for TSP and some trace metals, limitations in size distribution analysis may affect the estimation of PM concentrations.
ENVIRONMENTAL POLLUTION
(2021)
Article
Engineering, Chemical
Marie Choel, Anastasia Ivanovsky, Antoine Roose, Mona Hamze, Anne-Marie Blanchenet, Nicolas Visez
Summary: The coagulation of airborne particles on the surface of allergenic pollen grains is not well understood. This study quantitatively assessed the particulate deposition on allergenic pollen surfaces by sampling birch pollen grains (BPGs) during pollination. It was found that, on average, polluted BPGs carried 2 +/- 1 particles, representing an average surface coverage of 0.95%. The main coagulation process was hypothesized to be particle deposition by gravitational settling, although the effects of electric charges carried by pollen remain unknown. The presence of particle-polluted allergenic pollens appears to be common in the urban atmosphere, even under low air pollution conditions.
JOURNAL OF AEROSOL SCIENCE
(2022)
Review
Engineering, Environmental
Max G. Adam, Phuong T. M. Tran, Nanthi Bolan, Rajasekhar Balasubramanian
Summary: This passage discusses the impacts of smoke haze episodes caused by uncontrolled biomass burning in Southeast Asia, focusing on airborne particulate matter (PM). It reviews recent research on the environmental and health effects of BB-induced PM from 2010 to 2020, providing insights into the physical, chemical, toxicological, and radiative properties of BB-derived PM. Additionally, it outlines future research priorities and emphasizes the need for policies to prevent future BB events in the SEA region.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Review
Toxicology
Mengting Shang, Meng Tang, Yuying Xue
Summary: This review paper highlights the association between airborne particulate matter (PM) and neurodevelopmental toxicity (NDT), emphasizing the potential risks of blood-brain barrier damage and susceptibility to neurodevelopmental disorders. The research is important for understanding the impact of PM exposure on children's early brain development and identifying markers and mechanisms of PM-induced neurodevelopmental toxicity.
JOURNAL OF APPLIED TOXICOLOGY
(2023)
Article
Engineering, Environmental
Yang Xu, Linjun Qin, Guorui Liu, Minghui Zheng, Da Li, Lili Yang
Summary: The study assessed daily exposure levels of EPFRs for urban residents in Beijing, finding that carbon-centered radicals dominated in winter, while oxygen-centered radicals dominated in summer. Coal combustion in winter was identified as a key influencing factor, and an intuitive assessment concluded that one urban resident may inhale the equivalent of 46 cigarettes per day in EPFRs. Further research on the health risks of these free radicals, especially during winter, is recommended.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Engineering, Mechanical
Giovanni Straffelini, Stefano Gialanella
Summary: This paper focuses on the importance of non-exhaust emissions in urban areas, particularly the PM emissions from road vehicles' brake systems, and discusses the wear mechanisms at the pads-disc interface. Understanding the formation mechanisms of airborne PM is crucial for designing new friction material formulations with environmentally friendly ingredients.
Article
Biochemistry & Molecular Biology
Matheus Andrade Rocha Costa, Simone Andrade Gualberto, Polyany Cabral Oliveira, Iasnaia Maria de Carvalho Tavares, Nivio Batista Santana, Danilo Junqueira Leao, Debora Cardoso da Silva, Dhiessica Dos Santos Ribeiro, Neura Mendes da Silva, Pedro Henrique Santos, Mario Geraldo de Carvalho, Marcelo Franco
Summary: This study evaluated enzymatic pretreatment and hydrodistillation to increase the extraction efficiency of essential oil from Croton argyrophyllus leaves. The results showed that enzymatic pretreatment increased essential oil yield by 9.35% for fresh leaves and 6.77% for dry leaves under optimal experimental conditions. This approach holds promise for obtaining essential oil for therapeutic purposes without altering its composition.
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
(2022)
Article
Environmental Sciences
Maria Claudia R. Sola, Aldenor G. Santos, Madson M. Nascimento, Gisele Olimpio da Rocha, Jailson Bittencourt de Andrade
Summary: This study investigated the concentrations of polycyclic aromatic compounds in sediment samples from beaches in Salvador, Brazil. The results showed high levels of parent PAHs and nitro-PAHs, with a potent mutagenic compound found in most samples. Calculations of carcinogenic PAHs and risk assessments for benthic species indicated moderate risks in the sediments.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Chemistry, Analytical
Maria Elisabete Machado, Madson Moreira Nascimento, Pedro Victor Bomfim Bahia, Sabrina Teixeira Martinez, Jailson Bittencourt de Andrade
Summary: This study reviews the methods for assessing NSO-HET in sediments, examines the advantages and challenges, and discusses future trends and challenges to be overcome.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Pedro Victor Bomfim Bahia, Madson Moreira Nascimento, Jailson Bittencourt de Andrade, Maria Elisabete Machado
Summary: A green microscale solid-liquid extraction method was developed for the determination of n- alkanes in marine sediments. The method performance was validated and successfully applied to marine sediment samples.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Chemistry, Analytical
Caio S. A. Felix, Joao B. Pereira Junior, Jucelino B. da Silva Junior, Allan S. Cruz, Kelly G. F. Dantas, Sergio L. C. Ferreira
Summary: This study reports the mercury levels in fish samples purchased at a public market in Belem City, Brazil. The results showed that consuming 25g of these fish daily does not pose a risk to the local population's health.
Article
Chemistry, Analytical
Lindomar A. Portugal, Edwin Palacio, Rejane Frizzarin, Joao H. Santos Neto, Victor Cerda, Sergio L. C. Ferreira
Summary: This work proposes an automated strategy for the speciation of inorganic selenium in infusion tea samples. The system utilizes an MSFIA-CVG-AFS system and sodium tetrahydroborate for chemical vapor generation. The method involves an online prereduction step to convert selenium (VI) to selenium (IV) before determining the total selenium concentration. The chemical parameters were optimized using a fractional factorial design. The method exhibited low detection and quantification limits, with a linear range and good precision. This method was successfully applied to analyze inorganic selenium speciation in commercially purchased tea samples.
Review
Environmental Sciences
Natalia Menezes, Igor Cruz, Gisele O. da Rocha, Jailson B. de Andrade, Zelinda M. A. N. Leao
Summary: This study investigates the impact of petroleum exploitation and oil spills on coral reefs in marine ecosystems through a systematic review and bibliometric analysis. The main matrices studied are sediments, corals, and water, while air and other invertebrates have been less studied. Recommendations for future research include improving the detection capability of non-conventional PAHs, conducting more studies in underexplored regions in developing countries, and establishing databases to facilitate management planning.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Multidisciplinary Sciences
Fabio N. dos Santos, Madson M. Nascimento, Gisele O. da Rocha, Jailson B. de Andrade
Summary: We used MALDI-MS to investigate if pristine and functionalized fullerenes could be constituents of atmospheric aerosols. We identified several fullerene species, including C-60 and C-70, using matrix laser desorption ionization. The presence of these fullerenes as original constituents of atmospheric particles suggests their potential role in atmospheric chemistry and toxicity studies.
SCIENTIFIC REPORTS
(2023)
Article
Biochemical Research Methods
Pedro Victor Bomfim Bahia, Valdiria Almeida de Oliveira, Madson Moreira Nascimento, Leila Oliveira Santos, Gisele Olimpio da Rocha, Jailson Bittencourt de Andrade, Maria Elisabete Machado
Summary: This study presents the optimization and validation of a microscale extraction procedure for the determination of PANHs in PM2.5 samples, and it demonstrates low limits of detection and quantification as well as accurate and precise results. Additionally, the method is evaluated to be environmentally friendly and scored high in terms of greenness.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Madson Moreira Nascimento, Melise Lemos Nascimento, Jeancarlo Pereira dos Anjos, Ricardo Leal Cunha, Gisele Olimpio da Rocha, Ivanice Ferreira dos Santos, Pedro Afonso de Paula Pereira, Jailson Bittencourt de Andrade
Summary: Liquid-phase microextraction (LPME) is a simple, low-cost, and eco-friendly technique used to detect trace concentrations of organic contaminants in water samples. In this study, a novel customized micro-extraction device was developed for the extraction and preconcentration of illicit drugs in surface water and wastewater samples. The method was applied to real samples collected in Brazil, and the main drug detected and quantified was cocaine. The proposed method was considered environmentally friendly according to the AGREE metrics.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Environmental Sciences
Pedro Victor Bomfim Bahia, Madson Moreira Nascimento, Gisele Olimpio da Rocha, Jailson Bittencourt de Andrade, Maria Elisabete Machado
Summary: A green microscale solid-liquid extraction method was developed and applied for the analysis of 23 polycyclic aromatic sulfur heterocycles (PASHs) in PM2.5 samples. The optimal extraction conditions were determined through experimental design and successfully applied to samples collected from different time intervals and sulfur contents in diesel. The reduction of sulfur content in diesel showed a significant impact on the concentration of PASHs.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Multidisciplinary
Madson Moreira Nascimento, Sabrina Teixeira Martinez, Maria Elisabete Machado, Gisele Olimpio da Rocha, Jailson Bittencourt de Andrade
Summary: Baia de Todos os Santos (BTS) is the second-largest Brazilian bay and an important oil producing region in Brazil. This study presents recent research on contamination by polycyclic aromatic compounds (PACs) and Hg in the BTS region, focusing on sediments, water, and biota. The study also discusses the presence of different types of PACs, such as PAHs, nitro-PAHs, oxy-PAHs, and PASHs, as well as the distribution of Hg in seawater, sediments, and biota. The findings on biomonitoring organisms, including polychaetes, ascidians, and corals, are also discussed. The study concludes with suggestions for future research.
Article
Chemistry, Multidisciplinary
Marinice S. S. Acacio, Eliete C. Alves, Jailson B. de Andrade, Jeancarlo P. dos Anjos
Summary: Carbonyl compounds can be formed during craft beer production process, affecting sensory properties and posing a risk to health due to their toxicity. This study quantified 15 carbonyl compounds in craft beers, both in free and bound forms, using hydrolysis and derivatization reactions. The presence of acrolein, benzaldehyde, heptanal, and formaldehyde in craft beers suggests potential undesirable flavors. Frequent consumption of craft beers containing these carbonyl compounds could be harmful to health.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2023)
Review
Chemistry, Multidisciplinary
Lilian L. N. Guarieiro, Michelle J. C. Rezende, Willams T. Barbosa, Gisele O. da Rocha, Pedro Afonso P. Pereira, Daniella R. Fernandes, Wilson A. Lopes, Claudio J. A. Mota, Jailson B. de Andrade
Summary: Circular chemistry is an approach that aims to establish sustainable and circular chemical processes. It combines the principles of circular economy, life cycle approaches, and systems thinking to address sustainability issues. By promoting reuse, circular chemistry brings benefits in social, environmental, and economic spheres. It can contribute to constructing a mutually beneficial relationship between science, society, and the environment by maximizing benefits and reducing adverse impacts.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Sabrina T. Martinez, Caio S. A. Felix, Rayane Sorrentino, Igor C. S. Cruz, Jailson B. de Andrade
Summary: This study suggests that Phallusia nigra can be used as a potential biomonitor for mercury contamination. The study measured mercury levels in seawater and different parts of the ascidians from various sites in the Todos os Santos Bay. The results showed that the branchial basket had the highest concentration of mercury, followed by the hepatopancreas and tunic. Additionally, the branchial basket was the only tissue capable of identifying spatial differences in pollution between the sites.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).