Article
Chemistry, Analytical
Mostafa A. Atia, Petr Smejkal, Vipul Gupta, Paul R. Haddad, Michael C. Breadmore
Summary: This study demonstrates the superior performance of chemical vapour deposition (CVD) coating for suppressing the electroosmotic flow (EOF) compared to liquid phase deposition (LPD) in capillary electrophoresis (CE). By adjusting the modification method and surface chemistry, the capillary can be easily and effectively modified, and the stability of the coating meets the long-term monitoring requirements for water chemistry.
ANALYTICA CHIMICA ACTA
(2023)
Review
Biochemistry & Molecular Biology
Marcin Gackowski, Anna Przybylska, Stefan Kruszewski, Marcin Koba, Katarzyna Madra-Gackowska, Artur Bogacz
Summary: This review summarizes scientific reports from between 2010 and 2019 on the use of capillary electrophoresis for quantifying active constituents in medicinal plants and herbal formulations. The most commonly used technique is capillary electrophoresis with ultraviolet detection, which provides selective separation and quantification of bioactive compounds.
Article
Engineering, Chemical
Amna Khatoon, Nadir H. Khand, Arfana Mallah, Amber R. Solangi, Saima Q. Memon, Almas F. Memon, Ceren Karaman, Fatemeh Karimi, Onur Karaman
Summary: This study demonstrates the potential and utility of capillary electrophoresis for rapid size-based characterization of Ag NPs. By using specific buffer and voltage conditions, the size of Ag NPs can be analyzed based on electrophoretic mobility, providing comparable results with conventional techniques at a lower cost.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Biochemical Research Methods
Szymon Dziomba, Magdalena Wysocka, Joanna Jonca, Laura Sola, Aleksandra Stec, Krzysztof Waleron, Bartosz Wielgomas
Summary: The study evaluated the impact of selected parameters of CZE method on OMVs isolate analysis, finding that extending the sample injection plug length significantly improves the detectability of macromolecular aggregates in CZE, with negligible adsorption of OMVs to capillary walls. Additionally, the relaxation effect and deformation/polarization of vesicles were shown to affect OMVs electrophoretic mobility.
Review
Chemistry, Analytical
Jiri Salplachta, Anna Kubesova, Dana Moravcova, Filip Dusa
Summary: This article mainly focuses on the application of capillary electrophoresis (CE) in the analysis of yeasts and filamentous molds. It provides a brief introduction to the theoretical basis of CE, discusses the surface properties of fungal cells in relation to their charge, and presents the major difficulties encountered in CE of fungal species and the corresponding approaches to overcome these difficulties. The article also highlights some recent advances in fungal CE.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Review
Biochemical Research Methods
Finja Krebs, Holger Zagst, Matthias Stein, Ratih Ratih, Robert Minkner, Mais Olabi, Sophie Hartung, Christin Scheller, Blanca H. Lapizco-Encinas, Cari Sanger-van de Griend, Carlos D. Garcia, Hermann Waetzig
Summary: This article supports the development of selective, precise, fast, and validated capillary electrophoresis (CE) methods. It follows a similar article from 1998 and highlights the continuing relevance of its fundamentals while showcasing the significant achievements made in the last 25 years. With a focus on pharmaceutical and biological applications, the successful use of CE is demonstrated through over 600 carefully selected references, providing a comprehensive overview of the field. The article also includes sections on sample pretreatment, microchip CE, and a revised section on method development for protein analytes and biomolecules.
Article
Chemistry, Analytical
Natalia Kaczmarczyk, Julita Cizewska, Natalia Treder, Natalia Miekus, Alina Plenis, Piotr Kowalski, Anna Roszkowska, Tomasz Baczek, Ilona Oledzka
Summary: This study evaluates the impact of using ionic liquids (ILs) on the separation efficiency of biogenic amines (BAs) in micellar electrokinetic chromatography (MEKC). It found that ILs with chloride and tetrafluoroborate ions were the most effective, while ILs with trifluoromethanesulfonate and bis(trifluoromethylsulfonyl)imide ions disrupted the separation process. Overall, this study provides a critical assessment of the different types and concentrations of ILs in MEKC analysis of selected BAs.
Article
Chemistry, Analytical
Hebatallah M. Essam, Heba M. Mohamed
Summary: The combination of allopurinol and benzbromarone is a common gout treatment protocol, but patients often have suboptimal responses to allopurinol. Therefore, research on developing and optimizing a capillary zone electrophoresis method for determining the coformulation of these drugs and the active metabolite oxypurinol was conducted. The method was found to be ecofriendly and showed potential usefulness in biological and quality control labs.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Chemistry, Analytical
Abdelghani Mahmoudi, Silvia De Francia, Prasanta Paul
Summary: This study developed and validated a cost-effective and reliable HPLC method for quantifying clarithromycin in tablets. The proposed method showed good linearity, precision, accuracy, robustness, and specificity, and was comparable to capillary electrophoresis and bioassay methods. Therefore, it can be used as an alternative method for routine quality control of clarithromycin, especially when other methods are not accessible.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Chemistry, Analytical
Behrouz Seyfinejad, Abolghasem Jouyban
Summary: Accurate and reliable results are crucial in pharmaceutical and biomedical analyses. The combination of mass spectrometry and capillary electrophoresis shows great potential in these fields. This review provides an update on recent applications and methods of CE-MS relevant to biomedical and biopharmaceuticals, and discusses the latest developments in CE-MS and different CE modes.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Chemistry, Analytical
Laura Garcia-Cansino, Maria Luisa Marina, Maria Angeles Garcia
Summary: The research identified carboxymethyl-gamma-CD and sulfobutylated-I3-CD as the most advantageous selectors for the chiral separation of clopidogrel enantiomers. The addition of deep eutectic solvents and ionic liquids under optimized conditions showed an increase in chiral resolution.
MICROCHEMICAL JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Zvonimir Mlinaric, Lu Turkovic, Iva Begovic, Biljana Nigovic, Miranda Sertic
Summary: Advances have been made in treating HR+/HER2- breast cancer with CDK4/6 inhibitors. A novel and green capillary electrophoresis method for simultaneous determination of these inhibitors in less than 4 minutes is proposed. The method was validated for robustness, accuracy, and precision, and successfully applied to pharmaceutical dosage forms.
Article
Chemistry, Analytical
Amira F. El-Yazbi
Summary: Diabetes mellitus is a common chronic disease, often requiring combination therapy for glycemic control. A study established a simple and green method using capillary electrophoresis for the simultaneous determination of certain drugs in pharmaceutical forms. This method showed high separation efficiency and low solvent consumption, making it a green and cost-effective option for quality control analysis.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Pingjing Li, Lulu Wang, Rui Guo, Huatao Feng, Ya Ji, Si Ying Lim, Bao Hui Ng, Anna Karen Carrasco Laserna, Shaheer Khan, Shiaw-Min Chen, Sam Fong Yau Li
Summary: Recombinant protein biopharmaceuticals are important in current drug development, and the glycosylation profile of these proteins plays a crucial role in their quality. This study developed a CE-LIF method for accurate glycan identification by cross-identification using two capillary coatings and three labeling dyes. The use of homemade PVA and commercial coatings showed similar separation profiles, and the combination of fluorescent dyes provided better accuracy.
Article
Chemistry, Analytical
Yuliya Generalova, Nadezhda Sipkina, Galina Alekseeva
Summary: The new compound malaben exhibits pronounced activity in treating non-alcoholic fatty liver disease and could potentially be used as a drug. Various impurities in the malaben sample were studied and identified using electrophoretic separation and HPLC-ESI/MS analysis techniques, providing structural elucidation for some of the impurities.
MICROCHEMICAL JOURNAL
(2021)
Review
Food Science & Technology
Mayara Schulz, Siluana Katia Tischer Seraglio, Luciano Valdemiro Gonzaga, Ana Carolina Oliveira Costa, Roseane Fett
Summary: This review summarizes and discusses the factors affecting the phenolic composition and stability of Euterpe fruits, and emphasizes the importance of research and development of these fruits for the local economy.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Biotechnology & Applied Microbiology
Talyta Mayara Silva Torres, Simone Mazzutti, Marcos Antonio Castiani, Ilyas Siddique, Luciano Vitali, Sandra Regina Salvador Ferreira
Summary: The study focused on the microwave-assisted extraction of ora-pro-nobis leaves, showing high yield with 50% ethanol at 150 degrees C. Ethanol extracts at 110 degrees C exhibited the best antioxidant potential in DPPH and FRAP methods, while water extracts at 150 degrees C showed the best ABTS results. High total phenolic content recovery was found in 50% ethanol samples at 70 degrees C.
BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
(2022)
Correction
Biotechnology & Applied Microbiology
Talyta Mayara Silva Torres, Simone Mazzutti, Marcos Antonio Castiani, Ilyas Siddique, Luciano Vitali, Sandra R. S. Ferreira
BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
(2022)
Article
Food Science & Technology
Renan Danielski, Simone Mazzutti, Sandra Regina Salvador Ferreira, Luciano Vitali, Jane Mara Block
Summary: The recovery of phenolic antioxidants from agro-industrial by-products using non-conventional techniques is an effective approach to explore the bioactive potential of natural sources. This study found that ultra-turrax, ultrasonic bath, and pressurized liquid extraction are the most suitable methods for phenolic extraction from guava's pulp and processing waste. The extracts obtained have high antioxidant capacity and several compounds were discovered for the first time in the fruit.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2022)
Article
Food Science & Technology
Aline Krummel, Luiz Gustavo Goncalves Rodrigues, Luciano Vitali, Sandra Regina Salvador Ferreira
Summary: The antioxidant and antimicrobial properties of Pleurotus sajor-caju extracts were evaluated using different extraction methods. The results showed that sequential extraction using high-pressure methods combined with ethanol had the best performance. Furthermore, the selection of extraction processes and conditions could improve the quality of P. sajor-caju mushrooms.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Priscila Nehring, Siluana Katia Tischer Seraglio, Mayara Schulz, Fabiana Della Betta, Luciano Valdemiro Gonzaga, Luciano Vitali, Mayara da Silva, Gustavo Amadeu Micke, Ana Carolina Oliveira Costa, Roseane Fett
Summary: This study determined the physicochemical characteristics, mineral content, sugar content, phenolic compound content, and antioxidant capacity of grumixama fruits at different ripening stages and growing locations. The results showed that ripeness and growing location significantly influenced the nutritional and chemical properties.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Food Science & Technology
Samantha Goncalves, Luciano Molognoni, Heitor Daguer, Ricardo Pimenta, Rodrigo Barcellos Hoff, Gustavo Amadeu Micke, Luciano Vitali
Summary: This study developed an innovative method for sulfite inspection in seafood using capillary zone electrophoresis. The method is simple, fast, and allows for simultaneous extraction and deriva-tization of sulfite, suitable for high throughput analysis. The method showed selectivity and specificity when compared to liquid chromatography coupled to mass spectrometry. The results met the required parameters for metrological accreditation.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Pharmacology & Pharmacy
Nicole Esposto Biondo, Debora Fretes Argenta, Gabriela Schneider Rauber, Luciano Vitali, Thiago Caon
Summary: This study selected three natural terpenes classified as safe by FDA to enhance the transdermal delivery of testosterone. Among them, carvacrol showed the highest permeation flux and cutaneous retention of testosterone, making it the most effective chemical absorption enhancer (CAE).
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Biology
Marcello Rocha de BritoJnior, Fabio Zacouteguy Ugalde, Luciano Valdemiro Gonzaga, Mayara Schulz, Roseane Fett, Ana Carolina Oliveira Costa, Giustino Tribuzi
Summary: This study found that adding 10%, 20%, and 40% of jucara fruit pulp during the brewing process had a significant impact on the physicochemical parameters, total phenolic content, and antioxidant effect of the beers. The best result was achieved with the addition of 20% pulp at the maturation stage.
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Priscila Aparecida Horn, Ana Lucia Bertarello Zeni, Natalia Cavichioli, Evelyn Winter, Keila Zaniboni Siqueira Batista, Luciano Vitali, Eduardo Alves de Almeida
Summary: This study characterized the chemical composition of brewer's spent yeast (BSY) from two different beer productions and tested its cytotoxicity in various cell lineages. The results showed that BSY samples had similar lipid and ash content but slight differences in other nutritional components. BSY2 sample had higher concentrations of glucans and phenolic compounds. Both BSY1 and BSY2 extracts demonstrated similar antioxidant capacity and were not cytotoxic to most cell lines except PANC-1 cells. These findings suggest that brewery residue can be a value-added functional food with potential adjuvant role against PANC-1 cell lines.
EUROPEAN FOOD RESEARCH AND TECHNOLOGY
(2023)
Article
Chemistry, Applied
Marina Pereira-Coelho, Isabel Cristina da Silva Haas, Cassia Katrin Reinke, Jocinei Dognini, Renata Dias de Mello Castanho Amboni, Luciano Vitali, Luiz Augusto dos Santos Madureira
Summary: A simple sample preparation approach employing the dispersive pipette extraction (DPX) technique is proposed to determine twelve polyphenols in wines. The extraction parameters were optimized using univariate and multivariate designs. The analytical performance was satisfactory with high determination coefficients and good precision.
Article
Biochemistry & Molecular Biology
Alyne Lizane Cardoso, Luciane de Lira Teixeira, Neuza Mariko Aymoto Hassimotto, Sheyla de Liz Baptista, Candice Lais Knoner Copetti, Debora Kurrler Rieger, Francilene Gracieli Kunradi Vieira, Gustavo Amadeu Micke, Luciano Vitali, Maria Alice Altenburg de Assis, Mayara Schulz, Roseane Fett, Edson Luiz da Silva, Patricia Faria Di Pietro
Summary: This clinical trial evaluated the absorption and excretion of bioactive compounds in jucara juice and its antioxidant capacity in human serum. The study found that several phenolic acids and conjugated phenolic acids were excreted in urine, and jucara juice decreased the total oxidant status of serum. These findings suggest a relationship between the production of metabolites and the antioxidant capacity of jucara juice.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Applied
Pamela Pacassa Borges, Larissa Benvenutti, Aline Lana Schneider, Marcelo Rodrigo Franke Echterhoff, Bruna Goncalves Lopes, Diogo Alexandre Siebert, Gustavo Amadeu Micke, Luciano Vitali, Michele Debiasi Alberton, Nara Lins Meira Quintao, Jose Roberto Santin, Isabel Daufenback Machado
Summary: We investigated the anti-inflammatory activity of Myrcia pubipetala's crude hydroalcoholic extract (CHE-MP) and found that it significantly reduced the levels of nitric oxide, interleukin-1 beta, interleukin-6, and tumor necrosis factor in inflammatory cells. It also decreased neutrophil migration, indicating its potential as an anti-inflammatory agent.
NATURAL PRODUCT RESEARCH
(2023)
Article
Chemistry, Analytical
Diogo Alexandre Siebert, Natalia Bruzamarello Caon, Michele Debiasi Alberton, Luciano Vitali, Alexandre Luis Parize, Gustavo Amadeu Micke
Summary: This study proposes a novel enzyme micro-reactor using acetylcholinesterase anchored on magnetic nanoparticles and immobilized in capillaries using chitosan and glutaraldehyde. The enzyme showed a Km value of 1.12 mmol L-1, comparable to other immobilized enzyme studies. The method was also used to evaluate IC50 for neostigmine and showed good stability with at least 25 experiments possible. The method was applied to hydroalcoholic extracts of 7 plant species, with Plinia cauliflora showing the best enzyme inhibition of 42.31±6.81% at a concentration of 100 mg L-1.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Applied
Victor Rodrigues Alves, Samantha Goncalves, Heitor Daguer, Gustavo Amadeu Micke, Luciano Vitali
Summary: The rise in consumption of ultra-processed meat and dietary collagen supplements poses a challenge to food quality control. This study aimed to develop a new method using cyclodextrin-assisted electrokinetic chromatography with indirect UV detection to determine 4-hydroxyproline for collagen monitoring in dietary supplements and meat products. The method involved hydrolyzing samples with sulfuric acid and removing them using simultaneous neutralization/precipitation reactions with strontium carbonate. The method was successfully validated and proved to be a feasible alternative for quality control.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).