Article
Chemistry, Multidisciplinary
Zhaoqing Cai, Huijun Zou, Yirui Chen, Zheng Wang
Summary: In this study, a sample introduction technique based on SCGD of a portable design for ICP-OES was proposed for sensitive determination of mercury. The method achieved a detection limit of 0.22 μg/L, which was significantly lower than traditional pneumatic nebulization. The accuracy and practicality of the method were demonstrated through the analysis of various samples.
CHINESE CHEMICAL LETTERS
(2022)
Review
Chemistry, Multidisciplinary
Xiaoxu Peng, Zheng Wang
Summary: The article provides an overview of the development of solution electrode glow discharge (SEGD) in various fields and discusses its discharge mechanism. SEGD has unique advantages for optical emission spectrometry and mass spectrometry, and it has broad research potential in biology and medicine, material synthesis, electrochemistry, etc.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Analytical
Jiadeng Chen, Xiaoming Jiang, Yunfei Tian, Xiandeng Hou
Summary: The harm of heavy metals of microplastics to organisms mainly comes from the part adsorbed on their surface. A new simple in situ preconcentration method, using portable electrolyte atmospheric liquid discharge optical emission spectrometry (ISP-EALD-OES), was proposed for convenient on-site analysis of Cd on microplastics. The microplastic sample was centrifuged with 1% HNO3 to dissolve Cd species from the surface, and the Cd in the supernatant was determined using this method. After optimizing the experimental conditions, the limit of detection (LOD) for Cd was 1.5 ng mL(-1) using the corresponding aqueous standard. This could be a new strategy for field analytical chemistry of trace elements on microplastics' surfaces.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2023)
Review
Spectroscopy
Brian T. Molnar, Jacob T. Shelley
Summary: Plasmas have been used as ionization sources in mass spectrometry experiments since the early days of Thomson and Aston. Plasma ion sources were chosen because they were one of the few known sources of gas-phase ions at the time and were relatively easy to set up and operate. The development of plasma ionization has led to advancements in mass spectrometry and laid the foundation for ionization approaches, mass analysis, and detection methods for very large molecules.
MASS SPECTROMETRY REVIEWS
(2021)
Article
Chemistry, Analytical
Peichao Zheng, Yuanjiang Luo, Jinmei Wang, Qiang Hu, Yang Yang, Xuefeng Mao, Chunhong Lai
Summary: A refrigerating anode method was developed to enhance spectral signals and stability in SCGD-AES for the determination of metal elements. Compared to the unrefrigerated system, the detection limits for Ag, Cd, Cu, Mn, and Zn were significantly improved, and the method exhibited high accuracy and reliability in analyzing water samples. The results indicated that SCGD-AES coupled with a refrigerating anode could provide an effective analytical method for on-line determination of metal elements.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2021)
Article
Spectroscopy
Jaime Orejas, Yinchenxi Zhang, Cristian Soto-Gancedo, Luis Javier Fernandez-Menendez, Jorge Pisonero, Nerea Bordel
Summary: The Solution-Cathode Glow Discharge (SCGD) is a plasma source that provides simplicity and low consumption for elemental analysis. When combined with Optical Emission Spectrometry (OES), it can achieve ng/mL limits of detection for multiple elements. This study focuses on fundamental plasma diagnostics of SCGD and investigates how dissolved ions in the sample solution affect the performance of the analysis.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2023)
Article
Spectroscopy
Zhaoqing Cai, Zheng Wang
Summary: The use of solution anode glow discharge (SAGD) in hydrogen-helium mixture was evaluated for optical emission spectrometry (OES) of arsenic (As) in solution. The enclosed structure and non-electrode hollow channel were adopted to integrate the functions of vapor generation, atomization, and excitation of As. The study found that propionic acid had the best amplification effect, and the detection limit of SAGD-OES for As was better than that of the fully open-to-air discharge system. SAGD was more susceptible to chemical interferences induced by transition metal elements compared to alkali metals and alkaline earth metals.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2023)
Article
Spectroscopy
Jaime Orejas, Nicholas Hazel, Steven J. Ray
Summary: The solution-cathode glow discharge (SCGD) using a novel rectangular-shaped cathode capillary is employed to study aspects of the plasma-liquid interface, with high-speed video and low-angle laser scattering techniques used to evaluate potential mechanisms related to surface-plasma interaction. Frame-by-frame analysis of high-speed video allows estimation of droplet number density, translational speed, and rate of ejection, providing insight into potential analyte transport mechanisms important for analytical atomic spectrometry using SCGD.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Peichao Zheng, Yuanjiang Luo, Jinmei Wang, Yang Yang, Qiang Hu, Xuefeng Mao, Chunhong Lai
Summary: An improved micro-plasma source was developed for the quantitative analysis of heavy metal elements by solution cathode glow discharge-optical emission spectrometry (SCGD-OES). The source, fabricated using a geometrically optimized stainless steel auxiliary cathode solution and a tungsten anode, achieved optimum discharge at reduced solution flow rates. With detection limits for multiple heavy metal elements and good agreement in recoveries compared to ICP-OES, this study may contribute to the design of glow discharge sources for in situ determination of metal elements in complex water samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Monika Gorska, Pawel Pohl
Summary: Miniaturized atmospheric pressure glow discharge (APGD) microplasma devices operated in contact with a flowing liquid anode (FLA) or a flowing liquid cathode (FLC) and a He jet were used for determining the concentration of bromine (Br) through optical emission spectrometry (OES). The impact of crucial parameters on the intensity of the Br analytical line was studied and the analytical figures of merit were assessed under optimal conditions. The developed methods showed good endurance to matrix effects and were successfully applied for determining low concentrations of Br in water samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Yongsheng Ling, Zi Wang, Wenbao Jia, Qing Shan, Zhichao Zhang, Daqian Hei, Yu Wang
Summary: The determination of K, Na, and Mg in brine is crucial for its effective utilization. Liquid cathode glow discharge-optical emission spectrometry (LCGD-OES) is a successful method for this determination, but matrix interferences affect accuracy. This study reports a correction method based on mutual interferences to improve the accuracy of brine analysis.
ANALYTICAL LETTERS
(2023)
Article
Chemistry, Applied
Krzysztof Greda, Pawel Pohl
Summary: A new method of optical emission spectrometry (OES) using micmplasma source was developed for the determination of Na, K, Mg, Ca, and Zn in wine, without the need for acid digestion. The study also found that red wines have higher levels of K and Mg, and different grape varieties can be distinguished based on the concentrations of K and Ca.
Article
Chemistry, Analytical
Meng Zhang, Qingsong Tang, Peixia Li, Lin He, Xiandeng Hou, Xiaoming Jiang
Summary: A new compact tandem excitation source was designed and constructed using an array point discharge microplasma for a miniaturized optical emission spectrometer. The ArrPD microplasma was constructed by arranging three pairs of point discharges in sequence in a narrow discharge chamber, improving excitation capability through serial excitation. The enlarged discharge plasma region allowed for increased interception of gaseous analytes, leading to improved excitation efficiency and OES signal.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Meng Zhang, Qingsong Tang, Peixia Li, Lin He, Xiandeng Hou, Xiaoming Jiang
Summary: A new compact tandem excitation source was designed and constructed using an array point discharge microplasma for a miniaturized optical emission spectrometer. The ArrPD microplasma consisted of three pairs of point discharges arranged in sequence in a narrow discharge chamber, which significantly improved the excitation capability and efficiency. The proposed ArrPD source was compared to a commonly used microplasma source and showed 3-6-fold improvement in analytical sensitivities for seven elements.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Krzysztof Greda, Maja Welna, Anna Szymczycha-Madeja, Pawel Pohl
Summary: The technique of vapor generation assisted by a microplasma improves the sensitivity and reduces the detection limits in ICP OES. The microplasma system produces higher analyte fluxes and less water vapor, resulting in boosted signal intensities. The method is characterized by higher resistance to matrix effects and eliminates the use of toxic reductants.
Article
Environmental Sciences
Sheng-Nan Zhang, Yi Gu, Zhen-Li Zhu, Sheng-Hong Hu, Peter M. Kopittke, Fang-Jie Zhao, Peng Wang
Summary: The analysis of Cd isotope ratios in soil, rice grain, and human urine samples from two Cd-contaminated regions in southern China revealed a preferential enrichment of heavy Cd isotopes from soil to rice grain and from grain to urine. The fractionation of Cd isotopes in the soil-rice-human continuum is likely due to processes such as partitioning between the soil solid phase and soil solution, as well as preferential enrichment by metal transporters in humans.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Spectroscopy
George C-Y Chan, Leigh R. Martin, Lee D. Trowbridge, Zhenli Zhu, Xianglei Mao, Richard E. Russo
Summary: A study on direct enrichment assay of gaseous UF6 using LIBS revealed that vapor pressure of UF6 is a crucial parameter for analysis, with signal-to-background ratio influenced by gas pressure and laser energy. Optimization of experimental parameters is necessary to reduce the impact of self-absorption on accurate UF6 enrichment assay.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Fei-Yang Zhou, Dong He, Xin Miao, Chun Yang, Jun-Hang Dong, Hong-Tao Zheng, Zhuo Cheng, Xing Liu, Zhen-Li Zhu
Summary: The study presents a novel automatic column chromatography separation device for purifying samples for radiogenic and non-traditional stable isotope analysis. The device effectively controls droplets without the use of a pump, achieving accurate dripping of eluent under selected conditions and improving the recoveries of Sr and Cd samples. Overall, the proposed device demonstrates reliability and practicality in the automated purification of isotope samples.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Jun-Hang Dong, Chun Yang, Han-Qing Ding, Peng-Ju Xing, Fei-Yang Zhou, Huan Tian, Xing Liu, Hong-Tao Zheng, Sheng-Hong Hu, Zhen-Li Zhu
Summary: A portable, rapid, accurate, and cost-effective method for serum lithium determination was developed, utilizing MUN and APAD technologies, with detection completed in 40 seconds, no need for extra treatment of serum samples, and good tolerance to coexisting high concentration of other elements.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Chun Yang, Guo Cheng, Shuang-Quan Cheng, Xing Liu, Ying Liu, Hong-Tao Zheng, Sheng-Hong Hu, Zhen-Li Zhu
Summary: A novel method based on SAGD-OES was developed for the direct determination of trace Sb in water samples, offering advantages such as high sensitivity, simplicity, and operability at high pH. The proposed method demonstrated good tolerance to interferences and a low detection limit for accurate determination of antimony in real water samples.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Xing Liu, Guo Cheng, Chun Yang, Hong-Tao Zheng, Sheng-Hong Hu, Zhen-Li Zhu
Summary: A novel electrothermal desolvation-enhanced dielectric barrier discharge plasma-induced vapor generation (ETD-DBD-PIVG) method has been developed for sensitive determination of Sb. The method offers advantages such as simplified sample pretreatment steps and sensitivity for volume-limited sample analysis.
ANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Environmental
Weiqing Zhou, Aiguo Zhou, Bing Wen, Peng Liu, Zhenli Zhu, Zou Finfrock, Jianwei Zhou
Summary: This study investigates the isotope fractionation mechanism of Sb(V) adsorption onto gamma-Al2O3, showing a lack of equilibrium isotope fractionation during the adsorption process. The findings provide a valuable reference for future studies on Sb isotopes.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Analytical
Xing Liu, Linjie Chen, Huan Peng, Guan Wang, Nicholas Stanley Belshaw, Hongtao Zheng, Shenghong Hu, Zhenli Zhu
Summary: A fast, highly sensitive and cost-effective method for Cd isotopic analysis has been developed based on plasma electrochemical vapor generation (PEVG) coupled with MC-ICPMS. PEVG enhances sensitivity by more than 6 times compared with conventional pneumatic nebulization (PN) system and simplifies the complex purification process.
ANALYTICA CHIMICA ACTA
(2022)
Article
Spectroscopy
Zhifu Liu, Zhenli Zhu, Lanlan Jin, Shenghong Hu
Summary: A new online advanced oxidation process for the degradation of organic mercury was proposed. The method achieved complete degradation of organic mercury using a high-efficiency photooxidation reactor, without the need for oxidants and high temperature. It can be easily coupled with flow injection and high-performance liquid chromatography, and has low detection limits and good repeatability.
ATOMIC SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Ying Liu, Chun Yang, Peng-Ju Xing, Xing Liu, Jin-Zhao Liu, Zhen-Li Zhu
Summary: A new method based on hydrogen-doped solution anode glow discharge optical emission spectrometry (SAGD-OES) was developed for the direct detection of trace As in water samples. The method eliminates the use of a hydride generation (HG) sampling unit and only consumes low power, providing a promising approach for sensitive and rapid field As analysis. The proposed method was validated by the analysis of a certified reference material [GSB 07-3171-2014] and real water samples.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2023)
Article
Chemistry, Analytical
Junhang Dong, Jinzhao Liu, Pengju Xing, Shuyang Li, Jinsheng Piao, Huifang Tao, Lujie Li, Hongtao Zheng, Zhe Zhang, Shanru Han, Xing Liu, Zhenli Zhu
Summary: Sensitive and high-throughput analysis of trace elements in volume-limited biological samples is highly desirable for clinical research and health risk assessments. A novel high-efficiency and low-sample-consumption introduction device coupled with ICP-QMS was developed, achieving sensitive analysis at a low sampling rate with improved sensitivity compared to conventional methods. The proposed method offers fast washout and reduced sample consumption, and has been validated for various biological samples, showing potential in the field of metallomics.
ANALYTICAL CHEMISTRY
(2023)
Article
Geochemistry & Geophysics
Huan Peng, Peng Liu, Hongtao Zheng, Nicholas S. Belshaw, Shenghong Hu, Zhenli Zhu
Summary: Adsorption on mineral surfaces is a crucial process controlling the (bio)geochemical cycling of Cd. This study investigates the fractionation of Cd isotopes during Cd adsorption onto calcite, an important sink of Cd. The results show that the Cd isotope composition of calcite adsorbed components is lighter and consistent with equilibrium fractionation, and the observed fractionation is not influenced by various factors. The presence of PO43- affects the fractionation value, indicating its importance in interpreting Cd isotope signatures in nature.
Article
Chemistry, Analytical
Xing Liu, Guo Cheng, Chun Yang, Guan Wang, Shuyang Li, Yixiao Li, Hongtao Zheng, Shenghong Hu, Zhenli Zhu
Summary: A novel sensitive method for As determination was developed based on UV-assisted liquid spray dielectric barrier discharge (UV-LSDBD) plasma-induced vapor generation. UV irradiation greatly facilitates As vapor generation in LSDBD, leading to a 16-fold enhancement of the As signal. The method offers better tolerance to coexisting ions, with a detection limit of 0.13 μg/L and a relative standard deviation of 3.2% (n = 7). The accuracy and effectiveness of the method were further verified by analysis of reference and real water samples.
Article
Spectroscopy
Dong Jun-hang, Zhu Zhen-li, Ding Han-qing, Xing Peng-ju, Zhou Fei-yang, Zheng Hong-tao, Liu Xing
Summary: Isotope analysis plays a crucial role in various industrial fields, especially the nuclear industry, and has facilitated the development of geology, materials science, chemistry, and related disciplines. The optical isotope analysis method has gained increasing attention in recent years due to its unique advantages. It can meet the requirements of real-time and rapid analysis, and has been widely applied in the isotope analysis of environmental and geological samples. This review discusses the progress of optical isotope analysis methods, classified into emission spectroscopy and absorption spectroscopy, and compares them with traditional mass spectrometry methods. It also explores the prospects and technical challenges in optical isotope analysis.
SPECTROSCOPY AND SPECTRAL ANALYSIS
(2022)
Article
Chemistry, Analytical
Hai-tao Li, Xing Li, Ming Li, Wei Guo, Lan-lan Jin, Zhen-li Zhu, Qing-ye Hou, Sheng-hong Hu
Summary: Multi-isotope systems have great potential in tracing geological and environmental processes. A one-step method using AG MP-1M anion exchange resin is presented in this study to effectively separate Cu, Fe, Zn and Cd from complex matrix elements, with high recoveries and resolution. The obtained isotope ratios agree well with published values and new data for soil and sediment reference materials are reported for the first time. This one-step separation technique shows economic and efficiency advantages for simultaneous separation of multiple elements of interest in geological samples.
ANALYTICAL METHODS
(2022)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
