Article
Environmental Sciences
Siday Marrugo-Madrid, Manuel Salas-Moreno, Harry Gutierrez-Mosquera, Carlos Salazar-Camacho, Jose Marrugo-Negrete, Sergi Diez
Summary: To fulfill the requirements of the Minamata Convention on Mercury, it is important to monitor mercury contamination in freshwater ecosystems near artisanal and small scale gold mining (ASGM) areas. This study examined the feasibility of using the diffusive gradient in thin-films (DGT) technique to detect and quantify labile mercury and other metals in a hard-to-reach gold mining district in Colombia. The results showed that the labile mercury concentrations were higher in abandoned mining ponds compared to the river water, and the labile concentrations of other metals were related to their proximity to ASGM activities.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Karelys Umbria-Salinas, Astolfo Valero, Monica Wallner-Kersanach, Carlos Ferreira de Andrade, Maria Josefa Santos Yabe, Julio Cesar Wasserman, Katia Naomi Kuroshima, Hao Zhang
Summary: The study assessed seasonal variations in the concentrations of labile fractions of metals in shipyards located in estuarine areas on the Brazilian subtropical coast, indicating shipyards as hotspots of trace metals where Ecological Risk Assessment should be carried out.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Geochemistry & Geophysics
Nicole Mae M. Atienza, Daniel D. Gregory, Sandra D. Taylor, Megan Swing, Daniel E. Perea, Jeremy D. Owens, Timothy W. Lyons
Summary: The trace element chemistry of pyrite is important for understanding the formation of ore deposits, mineral exploration, and the evolution of Earth's chemistry. It is not clear whether trace elements are held within the pyrite structure or as nano-inclusions of other phases. This distinction is crucial as it affects the interpretation of trace element content.
GEOCHIMICA ET COSMOCHIMICA ACTA
(2023)
Review
Chemistry, Analytical
Katja Schmidt, Sophie A. L. Paul, Eric P. Achterberg
Summary: The geochemical behavior and bioavailability of trace metals are closely linked to their physical fractionation and chemical speciation. The DGT speciation technique allows for the challenging assessment of labile concentrations of various trace metals in ocean waters. This study demonstrates the applicability and sensitivity of DGT passive samplers for monitoring anthropogenic activities and studying natural processes in deep-sea environments.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Environmental Sciences
Miguel Caetano, Margarida M. Correia dos Santos, Nuno Rosa, Ines Carvalho, Jose German Rodriguez, Maria Jeusu Belzunce-Segarra, Iratxe Menchaca, Joana Larreta, Marta Rodrigo Sanz, Vanessa Millan-Gabet, Jean-Louis Gonzalez, Isabelle Amouroux, Stephane Guesdon, Florence Menet-Nedelec, Blanaid White, Fiona Regan, Martin Nolan, Brendan McHugh, Philippe Bersuder, Thi Bolam, Craig D. Robinson, Gary R. Fones, Hao Zhang, Marco Schintu, Natalia Montero, Barbara Marras
Summary: This study investigates the relationships among different chemical forms of Ni, Cd, and Pb in coastal and transitional waters across a broad geographical scale. The concentrations of metals vary greatly among sampling sites and methodologies, mainly due to natural water fluctuations. The labile fractions of Cd and Pb in spot samples are highly correlated, with Pb's labile fraction significantly lower than Cd's.
MARINE POLLUTION BULLETIN
(2022)
Article
Chemistry, Analytical
Yoshiki Makino, Hiroki Matsuo, Koichiro Masuda, Shun-ya Onozawa, Tetsuya Nakazato
Summary: The evaluation of metal leaching in metal-catalyzed reactions is crucial, but current analytical methods for trace metal determination in organic reaction solutions are time-consuming and require high purity reagents. In this study, a rapid and sensitive method using LA-ICP-MS was developed for the determination of platinum group elements (PGEs) in organic reaction solutions. The proposed method allows for quick detection without the need for pre-treatment and can be completed in a short amount of time. The accuracy and adaptability of this method were confirmed through comparison with conventional methods.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Chemistry, Analytical
Stefan Wagner, Jakob Santner, Johanna Irrgeher, Markus Puschenreiter, Steffen Happel, Thomas Prohaska
Summary: A method using DGT was developed for accurate quantification of trace-level Sr and Pb concentrations and isotope ratios in soils. The method utilizes a novel PTFE membrane binding layer with high selectivity for Sr and Pb. The study showed that the method performed well under various conditions and selective elution process allowed for purification of Sr and Pb fractions.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Sana M. Alahmadi, Salwa S. Aljuhani
Summary: Silica gel chemically functionalized with alizarin and 1-nitroso-2-naphthol was synthesized and used as SPE sorbents for the determination of Pb (II) ions. The synthesized resins showed high sorption efficiency and could remove more than 95% Pb (II) from solutions. The proposed method was successfully applied to the determination of Pb (II) in real groundwater samples.
Article
Chemistry, Analytical
Po Wang, Jonathan K. Challis, Zi-Xuan He, Charles S. Wong, Eddy Y. Zeng
Summary: The study evaluated the effects of biofouling on the uptake of PFAS by o-DGT samplers. Results showed that biofouling significantly reduced the sampling rates and accumulated masses of PFAS. However, under typical flowing conditions, the impact of biofouling on target PFAS sampling by o-DGT was not significant, suggesting the importance of monitoring biofilm thickness in situ over long periods of time.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2022)
Article
Biochemistry & Molecular Biology
Lisa Fischer, Bernadette Moser, Stephan Hann
Summary: Although not regulated in directives like the Water Framework Directive of the European Union, the investigation of geogenic background concentrations of certain elements such as precious metals is becoming increasingly important for early detection of potential environmental pollution. A methodological approach using matrix separation and pre-concentration on the strong anion exchange resin TEVA(R) Resin has been developed for the determination of Ag, Pt, Pd, and Au in groundwater.
Article
Thermodynamics
Pammi Raj Gupta, Pradyumna Ghosh, Jahar Sarkar
Summary: This study investigates the role of different types of probes in Radiofrequency ablation based thermal therapy for tumours and highlights the importance of fine-tuning probe characteristics for optimized treatment design and application. The results demonstrate that probe characteristics have a significant impact on treatment outcomes and tissue damage.
THERMAL SCIENCE AND ENGINEERING PROGRESS
(2023)
Article
Multidisciplinary Sciences
Patrick Janovszky, Albert Keri, David J. Palasti, Lukas Brunnbauer, Ferenc Domoki, Andreas Limbeck, Gabor Galbacs
Summary: The study emphasizes the importance of converting signal intensity maps of organic tissues collected by LIBS to elemental concentration maps. A machine learning methodology based on matrix-matched external calibration and linear discriminant analysis is proposed for this task. The results demonstrate the successful recognition of tissue types and conversion of intensity maps to accurate concentration maps for specific elements.
SCIENTIFIC REPORTS
(2023)
Article
Physics, Applied
Stefan Andrei Irimiciuc, Sergii Chertopalov, Michal Novotny, Valentin Craciun, Jan Lancok
Summary: Plasma diagnostic tools based on Langmuir probe and optical emission spectroscopy were used to investigate the copper halide plasma dynamics during the pulsed laser deposition process. The effect of argon gas addition on plasma dynamics was studied, showing changes in plasma parameters with increasing argon pressure. Space- and time-resolved optical emission spectroscopy confirmed plasma splitting and provided insight into the composition of the two-plasma structure.
JOURNAL OF APPLIED PHYSICS
(2021)
Article
Chemistry, Physical
Theo Pflug, Markus Olbrich, Jan Winter, Joerg Schille, Udo Loeschner, Heinz Huber, Alexander Horn
Summary: This article reports on the transient relative change of reflectance Delta R/R of stainless steel during and after ultrashort pulsed laser excitation, and the experimental results show that within the first picosecond after irradiation, the spatially resolved Delta R/R of stainless steel evolves into an annular shape with certain regions featuring decreased reflectance. The decreasing trend of Delta R/R is qualitatively supported by applying a two-temperature model.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Analytical
Laura German, Jill A. Mikucki, Susan A. Welch, Welch A. Kathleen, Anthony Lutton, Bernd Dachwald, Julia Kowalski, Dirk Heinen, Marco Feldmann, Gero Francke, Clemens Espe, W. Berry Lyons
Summary: Geochemical characterisation of hypersaline waters is challenging due to high salt concentrations hindering analysis of trace metals, but this study successfully analyzed trace metals in a subglacial brine from Antarctica using the IceMole probe. Detailed evaluation of the sampling impact of the IceMole and potential contributions of certain species from the probe were conducted, highlighting the importance of conducting chemical analyses for future exploration of deep subglacial lakes in Antarctica.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Article
Soil Science
Andrea Leptin, David Whitehead, Kate H. Orwin, Samuel R. McNally, John E. Hunt, Keith C. Cameron, Niklas J. Lehto
Summary: This study investigated the effects of high nitrogen addition on carbon rhizodeposition, the composition of main soil microbial groups, and microbial processing of rhizodeposited carbon for two grassland species. The results showed that high nitrogen addition increased rhizodeposited carbon concentration and caused compositional differences in soil microbial groups. The effects were more pronounced for one of the grassland species.
BIOLOGY AND FERTILITY OF SOILS
(2022)
Article
Environmental Sciences
Ines Tomasek, Hassina Mouri, Antoine Dille, George Bennett, Prosun Bhattacharya, Natacha Brion, Marc Elskens, Karen Fontijn, Yue Gao, Patrick Kirita Gevera, Julian Ijumulana, Mary Kisaka, Martine Leermakers, Ceven Shemsanga, Kristine Walraevens, Joanna Wragg, Matthieu Kervyn
Summary: This study reports the presence of potentially toxic elements (PTEs) in groundwater in the populated flanks of Mt. Meru in the East African Rift Valley, with most elements within acceptable limits for drinking water. However, some samples exceeded the WHO tolerance limits for Uranium and Molybdenum. The study emphasizes the need to expand monitoring of elements in regional groundwater and more routine measurement of PTEs for water safety and effective management.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Chemistry, Analytical
Yue Gao, Chunyang Zhou, Josep Galceran, Carlos Rey-Castro, Jaume Puy, Willy Baeyens, Martine Leermakers
Summary: This article reviews the application of Diffusive Gradients in Thin-films (DGT) in environmental studies, focusing on oxyanions and platinum group elements (PGEs). It summarizes the recent analytical advances in the development and use of DGT for these target element groups, while also highlighting the remaining knowledge gaps.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Environmental Sciences
Moussa Bouray, James L. Moir, Leo M. Condron, Niklas J. Lehto, Mohamed Bayad, Mohamed El Gharous, Khalil El Mejahed
Summary: Reasonable amounts of phosphogypsum (1 to 3 t ha(-1)) can help alleviate Al toxicity in acid soils (pH <= 5.3), but higher application rates should be avoided.
JOURNAL OF SOILS AND SEDIMENTS
(2022)
Article
Engineering, Environmental
Wei Guo, Jun Li, Mingyue Luo, Yan Mao, Xiangyi Yu, Marc Elskens, Willy Baeyens, Yue Gao
Summary: Effluents from sewage treatment plants are a significant source of estrogenic substances in water bodies, and this study assessed the presence of steroids, BPA, and phthalates in the effluents of three urban treatment plants in Beijing. The results showed that the concentrations and activities of estrogenic compounds were lower in the tertiary effluent compared to the secondary effluent. The study also revealed the removal mechanisms for these compounds, with biodegradation playing a significant role for some compounds while others were removed through adsorption and sedimentation.
Article
Environmental Sciences
Vendula Smolikova, Natacha Brion, Tianhui Ma, Vincent Perrot, Yue Gao, Pavlina Pelcova, Andrea Ridoskova, Martine Leermakers
Summary: The distribution and geochemistry of arsenic in water and sediments of the Zenne River, a small urban river in Brussels, were investigated. The study found that arsenic concentrations increase downstream, driven by the tidal cycle. Different arsenic species in water and sediment were assessed using DGT technique, and a point source on the tributary Tangebeek was identified as a major contributor to arsenic load in the Zenne River.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Mingyue Luo, Chunyang Zhou, Tianhui Ma, Wei Guo, Lawrence Percival, Willy Baeyens, Yue Gao
Summary: This study investigated the impact of dumping of dredged sludge, shipyard activities, and the mixing of polluted estuary water with less polluted coastal water on the mobilization of trace metals and oxyanions in marine sediments. The results showed that these anthropogenic activities have a significant influence on the levels, distribution, and bioavailability of contaminants in the sediments, posing a real threat to the benthic ecosystem.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Analytical
Krishantha Kodithuwakku, Jianyin Huang, Casey L. L. Doolette, Sean Mason, John Boland, Enzo Lombi, Niklas J. J. Lehto, Peter R. R. Teasdale
Summary: The availability of soil nitrogen for plant uptake can be affected by various soil factors, and conventional extraction techniques may affect the measurement of plant-available N concentrations. The diffusive gradients in thin-films (DGT) technique can overcome these limitations and has been successfully used to estimate the plant-available fractions of nutrients in soils. Therefore, evaluating the use of DGT for measuring NO3- and NH4+ in different soils and examining the factors affecting the plant-availability of these ions in soils is important.
ENVIRONMENTAL CHEMISTRY
(2022)
Article
Engineering, Environmental
Jordi Sans-Duno, Joan Cecilia, Josep Galceran, Jaume Puy, Willy Baeyens, Yue Gao
Summary: Determining species, concentrations, and physicochemical parameters in natural waters is important for understanding ecosystem functioning. The use of DGT devices with different thicknesses of the resin or diffusive disc provides independent information on relevant parameters. This study presents a method for determining dissociation rate constants of metal complexes and estimating metal bioavailability in environmental waters.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Agronomy
M. J. Gutierrez-Gines, N. J. Lehto, E. Madejon, B. H. Robinson
Summary: Incorporating biosolids into the soil improves plant yield compared with surface application, but it can result in the increased uptake of trace elements. This study aimed to determine the effect of the type and rate of biosolids application on soil quality and the mobility of contaminants.
Article
Environmental Sciences
Vincent Perrot, Tianhui Ma, Delphine Vandeputte, Vendula Smolikova, Arne Bratkic, Martine Leermakers, Willy Baeyens, Yue Gao
Summary: This study reports on the species and levels of mercury in the surface waters of the Scheldt Estuary and the Belgian Part of North Sea. The concentration of mercury on suspended particles gradually decreased along the estuary with increasing salinity and was strongly correlated with organic matter content and origin. In the North Sea, a significant fraction of total mercury occurs in a soluble form, potentially available for microorganisms. The results highlight the important contribution of the Scheldt estuary to the mercury budget in North Sea coastal waters and emphasize the need for seasonal monitoring of all mercury species.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Tianhui Ma, Willy Baeyens, Martine Leermakers, Vendula Smolikova, Mingyue Luo, Guanlei Li, Delphine Vandeputte, Vincent Perrot, Yue Gao
Summary: The geochemical behavior of metals in water and sediment in the tidal section of the Zenne River in Belgium was investigated. Sampling campaigns were conducted in October 2013 and March 2021 to analyze the metal concentrations under dry and rainy weather conditions. The study found that the Zenner River is a main source for Fe, Mn, Pb, Cr, Ni, and Zn, but other sources, including upstream transport, may explain the behavior of Co, Cd, and Cu during a tidal cycle. The research also highlighted the importance of rainfall and wind gust events in trace metal distribution and the contamination of sediments in the tidal Zenne.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Si -Si Liu, Yu -Wei Jia, Xiao-Yuan Guo, Jian-Liang Zhao, Yue Gao, Andy J. Sweetman, Guang-Guo Ying, Li Xu, Chen Tu, Chang -Er Chen
Summary: In this study, the adsorption and desorption kinetics of triclosan on polystyrene (PS) and polyvinyl chloride (PVC) were investigated using batch experiments and the diffusive gradients in thin-films (DGT) technique. The results showed that both intraparticle diffusion and external liquid film diffusion affected the adsorption and desorption processes. The DGT results indicated some restrictions to the desorption of triclosan from microplastic suspensions. Additionally, pH and ionic strength had significant effects on the supply of triclosan to DGT, either independently or interactively.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Hayley Jensen, Niklas Lehto, Peter Almond, Sally Gaw, Brett Robinson
Summary: Technological development has increased the use of rare trace elements (RTEs) as environmental contaminants, but their mobility in the soil-plant system is not well understood. This study investigated the tolerance and accumulation of RTEs by Lolium perenne and found that beryllium and lanthanum are the most likely to enter the food chain.
Article
Environmental Sciences
Markus Dengg, Claudine H. Stirling, Karl Safi, Niklas J. Lehto, Susanna A. Wood, Kyyas Seyitmuhammedov, Malcolm R. Reid, Piet Verburg
Summary: This study evaluates the role of iron in regulating phytoplankton growth in lakes of different nutrient status in New Zealand. The study identifies the thresholds for bioavailable and colloidal iron that control algal bloom formation and carbon sequestration in lakes.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).