Article
Engineering, Environmental
Clare Mills, Michael J. Dillon, Prabir Kumar Kulabhusan, Diana Senovilla-Herrero, Katrina Campbell
Summary: A multiplex lateral flow immunoassay has been developed to detect marine biotoxins, with specific antibodies for each toxin group. The assay is capable of accurately detecting okadaic acid, saxitoxin, and domoic acid within EU regulatory limits. It offers a simple and portable solution for toxin screening in shellfish.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Medicinal
Guo-Fang Duan, Yang Liu, Li-Na Zhang, Hong-Ye Li, Jie-Sheng Liu, Wei-Dong Yang
Summary: The study found that cinnamaldehyde can effectively reduce the accumulation of diarrhetic shellfish toxins in Perna viridis and decrease the histological alterations caused by DSTs in the mussel's digestive gland. Furthermore, cinnamaldehyde may decrease DSTs accumulation by suppressing CYP3A4 induction.
Article
Chemistry, Analytical
Celia Lhoste, Margherita Bazzoni, Justine Bonnet, Aurelie Bernard, Francois-Xavier Felpin, Patrick Giraudeau, Jean-Nicolas Dumez
Summary: In this study, ultrafast 2D NMR schemes were developed to acquire full spectral width 2D NMR spectra from continuously flowing samples in a short time. By using an interleaved acquisition strategy and an optimized solvent suppression strategy, it was possible to monitor chemical reactions online at high time resolution.
Article
Chemistry, Analytical
Celia Lhoste, Margherita Bazzoni, Justine Bonnet, Aurelie Bernard, Francois-Xavier Felpin, Patrick Giraudeau, Jean-Nicolas Dumez
Summary: This article presents a method for rapid acquisition of broadband homonuclear 2D NMR spectra from continuously flowing samples. The use of interleaved acquisition and optimized solvent suppression allows for obtaining full spectra width in a short period of time. This development is important for online monitoring with high time resolution using flow 2D NMR.
Article
Biochemical Research Methods
Elliott J. Wright, Pearse McCarron
Summary: A freeze-dried mussel tissue-certified reference material containing a complex profile of marine algal toxins was analyzed using liquid chromatography-high-resolution mass spectrometry. Over one hundred toxin analogues were identified, including previously unreported compounds, through a series of targeted and untargeted MS/MS experiments.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Marine & Freshwater Biology
Nancy I. Lewis, Rencheng Yu, Cheryl Rafuse, Michael A. Quilliam
Summary: A three-year field study was conducted in a mussel aquaculture site in Ship Harbour, Nova Scotia, Canada to detect toxic phytoplankton species and dissolved lipophilic phycotoxins and domoic acid. Plankton monitoring and SPATT techniques were used for analysis. The results showed seasonal changes in toxin composition were related to specific phytoplankton cell concentrations. SPATT samplers deployed within the mussel farm detected lower concentrations of phycotoxins compared to those deployed outside the farm.
Article
Toxicology
Yang Liu, Yang Lu, Yu-Hu Jiao, Da-Wei Li, Hong-Ye Li, Wei-Dong Yang
Summary: In this study, the effects of Okadaic acid (OA) on the metabolism of gut bacteria in rats were analyzed using a multi-omics strategy and rRNA high-throughput technology. The study found that OA had significant effects on gut bacteria, causing changes in dominant genera and bacterial function genes. It was also discovered that OA could be transformed into other metabolites, such as dinophysistoxin-2 (DTX-2), in the gut. The findings provide important insights into the complex toxicity of OA and its environmental fate.
ARCHIVES OF TOXICOLOGY
(2022)
Article
Automation & Control Systems
Yang Wu, Yanyong Yang, Qiuqiong Lin, Qinghao Zhang, Pinjia Zhang
Summary: This article proposes a novel online monitoring method for underground power cable insulation based on resonance frequency analysis under chirp signal injection, aiming to address the overlooked variation of insulation conductance. An online monitoring scheme based on common-mode chirp signal injection is designed, realizing nonintrusive online monitoring. The resonance frequency under the injected signal is then analyzed to effectively monitor insulation capacitance. Simulations and experiments prove the effectiveness of the proposed method for different system operating conditions.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2023)
Article
Engineering, Electrical & Electronic
Rohail Hassan, Hongjie Wang, Regan Zane
Summary: With increasing penetration rate of renewable energy and electric vehicles, dc microgrids that integrate zero-carbon-emission elements and reduce system costs are gaining more attention. This article proposes an online continuous small-signal stability monitoring method for dc microgrids, which evaluates stability by measuring the crossover frequency and phase margin of the system impedance minor loop gain. Detailed system modeling and analysis are presented, and experimental results validate the effectiveness of the proposed method.
IEEE TRANSACTIONS ON POWER ELECTRONICS
(2023)
Article
Engineering, Petroleum
Anton Gryzlov, Sergey Safonov, Muhammad Arsalan
Summary: Monitoring production rates is crucial for reservoir management, history matching, and production optimization. This paper discusses the application of continuous deep learning models for estimating oil, gas, and water rates. The models combine the time evolution properties of a dynamical system and the capability of neural networks to describe multiphase phenomena, making it a hybrid solution between data-driven and mechanistic approaches.
Article
Biophysics
Chenyan Zheng, Mingming Yin, Rui Ge, Jie Wei, Bingyuan Su, Xi Chen, Xiaomei Chen
Summary: A novel competitive near-infrared-mediated photoelectrochemical immunosorbent assay (cNIR-PECIA) was developed for ultrasensitive and highly selective detection of okadaic acid (OA) in shellfish, successfully applied for OA content analysis in mussel samples. The study suggests the potential applicability of this method in food safety analysis.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Food Science & Technology
Olga D. Hendrickson, Elena A. Zvereva, Anatoly Zherdev, Boris B. Dzantiev
Summary: In this investigation, a new approach for developing a sensitive lateral flow immunoassay (LFIA) for the detection of the hazardous marine toxin okadaic acid (OA) was proposed. The method utilizes an indirect format with anti-species antibodies labeled by gold nanoparticles (AuNPs) and cascade signal amplification. The developed test system showed improved detection limit and cutoff compared to LFIA without amplification. It has potential applications in point-of-care monitoring of samples for phycotoxin contamination and highly sensitive detection of trace amounts of contaminants.
Article
Psychology, Multidisciplinary
Hong Zhao, Asif Khan
Summary: This research investigates the impact of flow experience on online students' intention to engage in online English teaching platforms. The results show that perceived enjoyment, challenge, and situational involvement have a positive relationship with flow experience, while confirmation and perceived vividness do not have a significant effect. Furthermore, flow and confirmation are significantly related to perceived usefulness and satisfaction. Perceived usefulness is also significantly related to satisfaction and continuous intention.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Automation & Control Systems
Yang Wu, Yanyong Yang, Zhiyuan Wang, Pinjia Zhang
Summary: An online monitoring method for underground power cable insulation based on common-mode (CM) signal injection is proposed in this article. It provides an estimation of the insulation ageing severity using a feature extraction method.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2022)
Article
Engineering, Marine
Giuseppa Lorenzoni, Anna Maria Bazzoni, Monica Cangini, Sonia Dall'Ara, Rita Melillo, Alessandro Graziano Mudadu, Simona Cau, Barbara Soro, Salvatore Ledda, Gabriella Piras, Tiziana Tedde, Sara Salza, Igor Arras, Giuseppa Porqueddu, Domenico Meloni
Summary: Bivalve mollusk production is the main aquaculture activity in Sardinia. In 2021, 859 water samples and 1270 mollusk samples were analyzed. Alexandrium minutum and Dinophysis acuminata complex were found to cause toxin accumulation in bivalve mollusks. LC-FLD and LC-MS/MS analysis methods were used to study Paralytic Shellfish Toxins (PSTs) and lipophilic toxins (LTs) respectively. The presence of Dinophysis and Prorocentrum species was correlated with the accumulation of LTs in bivalve mollusks.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2023)
Article
Electrochemistry
Maham Liaqat, Sara Riaz, Mian Hasnain Nawaz, Mihaela Badea, Akhtar Hayat, Jean Louis Marty
Summary: The importance of developing multifunctional nanohybrid materials for sensing technologies is increasing with the development of nanotechnology. A novel nanohybrid electro-active material has been integrated into an electrochemical aptasensor, showing relatively less complex, highly sensitive, and multi-functional design. Real sample analysis in spiked wheat samples demonstrated the real-life applicability of the designed aptasensor with linear range, low LOD, and LOQ for Ochratoxin A detection.
ELECTROCHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Selma Rabai, Ahlem Teniou, Gaelle Catanante, Messaoud Benounis, Jean-Louis Marty, Amina Rhouati
Summary: A label-free electrochemical aptasensor for cadmium detection in water was developed using a nanocomposite combining gold nanoparticles, carbon nanotubes, and chitosan. The biosensor exhibited excellent performances for cadmium detection with high sensitivity, low detection limit, and a wide linear range. It also showed good selectivity against interfering ions.
Article
Chemistry, Medicinal
Marjan Majdinasab, Mihaela Badea, Jean Louis Marty
Summary: The lateral flow assay (LFA) is a widely used paper-based platform for rapid and on-site detection of various analytes. While antibodies are traditionally used in LFAs, they have limitations such as poor stability and high cost, making aptamers a promising alternative for biorecognition molecules in LFAs.
Article
Chemistry, Analytical
Xiaoqian Tang, Qi Zhang, Maria Isabel Pividori, Zhaowei Zhang, Jean-Louis Marty, Gaelle Catanante
Summary: Patulin contamination is a serious health risk factor for food safety and human health. In this study, a sensitive aptamer-based lateral flow assay was developed for rapid and simple patulin detection in apple juice.
Article
Chemistry, Analytical
Velia Osuna, Alejandro Vega-Rios, Erasto Armando Zaragoza-Contreras, Ivan Alziri Estrada-Moreno, Rocio B. Dominguez
Summary: Polyaniline-based glucose sensors (PBGS) are sensing systems with advantages such as conductivity, biocompatibility, and environmental stability, which can be used for blood glucose monitoring in diabetes patients. This review provides an overview of the development of PBGS from 2015 to the present, covering advancements and achievements in enzymatic and non-enzymatic PBGS for self-monitoring and continuous blood glucose monitoring, as well as discussing the limitations and challenges associated with this technology.
Article
Chemistry, Applied
Xiaoqian Tang, Gaelle Catanante, Xiaorong Huang, Jean-Louis Marty, Hong Wang, Qi Zhang, Peiwu Li
Summary: This study successfully devised a nontoxic electrochemical immunosensor for the quantitative determination of aflatoxin M-1. The immunosensor demonstrated good selectivity and sensitivity, making it suitable for practical applications such as milk samples.
Article
Biochemistry & Molecular Biology
Alain Salvador Conejo-Davila, Carlos Rafael Casas-Soto, Eider Pedro Aparicio-Martinez, David Chavez-Flores, Victor Hugo Ramos-Sanchez, Rocio Berenice Dominguez, Velia Carolina Osuna, Anayansi Estrada-Monje, Alejandro Vega-Rios, Erasto Armando Zaragoza-Contreras
Summary: In this research, a brush-like polyaniline (BL PAni) was developed to overcome the limitations of conventional polyaniline (PAni) in processability and dedoping at high pH. The synthesis of BL PAni involved grafting PAni chains using different polymerization methods, and the structure was confirmed by spectroscopic techniques. The thermal properties were analyzed, and the BL PAni showed absorption properties in the visible and near-infrared regions, as well as resistance to dedoping at high temperature and neutral pH. The absorption range and electroactivity were studied, highlighting the potential applications of BL PAni in various fields.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Chemistry, Medicinal
Marjan Majdinasab, Jean Louis Marty
Summary: The early diagnosis of diseases is crucial for effective treatment, and biomarkers offer great potential in this area. Aptamer-based biosensors, with their high sensitivity and selectivity, have emerged as a promising diagnostic tool. Electrochemical aptasensors have attracted significant attention due to their high sensitivity and accuracy in biomarker detection.
Review
Chemistry, Medicinal
Amina Rhouati, Adel Rhouati, Jean Louis Marty
Summary: Detection and quantification of biomarkers in biological fluids are crucial for screening, diagnosing, and treating diseases. Aptamers have recently emerged as an alternative to antibodies for sensing various biomarkers. With different transducers, aptamers offer simple and rapid tools for highly sensitive and selective detection. This review focuses on the use of aptamers in biosensing cardiac biomarkers, specifically Troponin I, B-type natriuretic peptide, and myoglobin. The principles and characteristics of electrochemical aptasensors reported in the literature over the past five years are also discussed.
CURRENT TOPICS IN MEDICINAL CHEMISTRY
(2022)
Article
Computer Science, Artificial Intelligence
Ruben I. Carino-Escobar, Gustavo A. Alonso-Silverio, Antonio Alarcon-Paredes, Jessica Cantillo-Negrete
Summary: Tree ensemble algorithms, like random forest, are widely used in machine learning, but the number of trees in the ensemble is an important hyperparameter. A new algorithm called feature-ranked self-growing forest (FSF) is introduced, which automatically grows the ensemble based on the structural diversity of the trees' nodes. The performance of FSF was tested with classification and regression datasets and compared to random forest, showing superior performance in most cases.
NEURAL COMPUTING & APPLICATIONS
(2023)
Article
Chemistry, Analytical
V. Sunil Kumar, Shekher Kummari, Gaelle Catanante, K. Vengatajalabathy Gobi, Jean Louis Marty, K. Yugender Goud
Summary: A label-free electrochemical impedimetric immunosensor was developed for rapid and sensitive detection of zearalenone (ZEN) using palladium nanoparticle embedded functionalized carbon nanotube-chitosan (SPCE/CS-CNT-Pd) modified electrode. The structure of the nanocomposite was analyzed and verified using X-ray diffraction, transmission electron microscopy, and energy dispersive X-ray spectroscopy. The coexistence of Pd nanoparticles with CNTs enhanced the conductivity and catalytic properties of the transducer surface, as well as improved antibody immobilization. The immunosensor showed high sensitivity and simplicity compared to conventional methods and successfully detected ZEN in corn samples with good recovery values.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Rabia Batool, Sara Riaz, Shehar Bano, Akhtar Hayat, Muhammad Shahid Nazir, Muhammad Nasir, Jean Louis Marty, Mian Hasnain Nawaz
Summary: A flexible CeO2 nanostructured polydopamine-modified carbon cloth (CeO2/PDA/CC) interface was fabricated for ethanol detection. The fabrication method involved electrodeposition of dopamine on carbon fibers followed by electrochemical growth of CeO2 nanoparticles. The CeO2/PDA-based electroactive interface exhibited impressive electrochemical performance due to the synergistic effect of PDA functionalization and active sites. The CeO2 nanostructures anchored on conductive CC contributed to superior electrocatalytic performance. The designed electrochemical sensor showed wide response range, low detection limit, good anti-interference ability, and excellent repeatability and reproducibility, making it suitable for practical implementation in saliva samples.
Review
Chemistry, Analytical
Jagadeeswara Rao Bommi, Shekher Kummari, Kavitha Lakavath, Reshmi A. Sukumaran, Lakshmi R. Panicker, Jean Louis Marty, Kotagiri Yugender Goud
Summary: Cancer is a significant global public health issue, accounting for the second highest number of deaths, especially in low- and middle-income countries. It has a huge economic burden of over a trillion dollars annually. Early detection plays a crucial role in effective treatment and improved survival rates, as a large percentage of cancers are diagnosed at late stages. Biosensors offer promise in the early screening of cancer biomarkers. This review highlights recent findings of novel cancer biomarkers, their advantages over traditional biomarkers, and innovative biosensing and diagnostic methods, aiding in early recognition and treatment monitoring of various human cancers.
Review
Chemistry, Analytical
Marjan Majdinasab, Marc Lamy de la Chapelle, Jean Louis Marty
Summary: Interleukin 6 (IL-6) is a pleiotropic cytokine that exerts pathological pro-inflammatory effects and plays important roles in various biological processes. The detection of IL-6 in small quantities with high selectivity is crucial in medical and biological fields. Conventional laboratory methods such as ELISAs and CLIAs are complex, expensive, and time-consuming, while biosensors offer a simple, rapid, economical, and user-friendly alternative due to their high sensitivity, quick detection time, ease of use, and miniaturization capability.
Article
Chemistry, Analytical
Ahlem Teniou, Ibrahim A. Madi, Riane Mouhoub, Jean Louis Marty, Amina Rhouati
Summary: In this study, a homogeneous technique was developed for sensitive and rapid quantification of hydrogen peroxide using hemoglobin as a bioreceptor. The chemiluminescence reagent luminol served as a peroxidase substrate and generated a chemiluminescent signal when oxidized by hemoglobin. The biosensor demonstrated high selectivity and a detection limit of 0.308 mM, making it a cost-effective and simple method for monitoring peroxidase substrates.
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).