Article
Chemistry, Analytical
Awadh O. AlSuhaimi, Khalid Althumayri, Hussain Alessa, Ali Sayqal, Amal T. Mogharbel, Bandar R. Alsehli, Nashwa M. El-Metwaly
Summary: This research presents the development and electroanalytical performance of a novel carprofen voltammetric carbon paste electrode (CPEs). The electrode matrix is fortified with zeolite nanostructures, resulting in an effective electrocatalytic activity that facilitates the oxidation of carprofen molecules. The proposed electrooxidation mechanism involves the oxidation of the enamine N atom through the transfer of delocalized lone pair of electrons, along with the participation of one proton. The utilization of ZY/CPEs allows for simultaneous quantification of carprofen in the presence of various interferents and degradation products, with high sensitivity and selectivity. The presented voltammetric analytical technique exhibits comparable recovery values compared to official chromatographic techniques for monitoring carprofen residues in veterinary and biological samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Electrochemistry
Salhah D. Al-Qahtani, Enas Aljuhani, Reem Shah, Samar Y. Al-nami, Zehbah A. Al-Ahmed, Mohamed E. Khalifa, Nashwa M. El-Metwaly
Summary: In this study, a novel carbon paste electrode incorporated with reduced graphene oxide (rGO) was used for sensitive adsorptive voltammetric determination of oxfendazole (OXF) in veterinary formulations and spiked milk samples. The electrode exhibited reversible electrooxidation behavior of OXF with mixed adsorption-diffusion mechanism. Linear calibration curves were constructed with a wide concentration range and a low LOD value. The rGO-based sensors showed improved sensitivity, reproducibility, operational lifetime, and shelf lifetime compared to reported OXF sensors. The fabricated sensors were successfully applied in the quantification of OXF in veterinary formulations and spiked milk samples with high accuracy and precision.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
Pablo Manuel Martinez-Rubio, Maria Dolores Aviles, Joaquin Arias-Pardilla, Francisco Jose Carrion-Vilches, Jose Sanes, Maria Dolores Bermudez, Ramon Pamies
Summary: A new series of nanofluids based on graphene dispersed in 2-hydroxyethylammonium lactate (ML) ionic liquid was developed. The concentration of graphene and temperature showed significant effects on the viscoelastic behavior and conductivity of the nanofluids. The viscosity unexpectedly decreased with a low concentration of graphene, while shear thinning effects appeared with higher concentrations. The complex Burgers model was used to describe the creep-recovery behavior of the nanofluid with 1 wt% of graphene.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Nanoscience & Nanotechnology
Venkatachalam Vinothkumar, Manickavasagan Abinaya, Shen-Ming Chen, Venkatachalam Sethupathi, Velluchamy Muthuraj
Summary: The study successfully synthesized perovskite-type silver titanate (Ag2TiO3) using ultrasound-assisted coprecipitation method and conducted a series of structural and performance analyses. The results demonstrated that the prepared Ag2TiO3 exhibited excellent electrochemical performance, sensitivity, and selectivity in metronidazole detection.
PHYSICA E-LOW-DIMENSIONAL SYSTEMS & NANOSTRUCTURES
(2021)
Article
Chemistry, Analytical
Ghada M. G. Eldin, Mohamed E. Khalifa, Alaa M. Munshi, Afrah M. Aldawsari, Nashwa M. El-Metwaly
Summary: This study proposed a novel analysis protocol for the sensitive differential pulse voltammetric determination of nadifloxacin, with improved performance of the working carbon paste electrodes by incorporating different carbonaceous nanomaterials. Through optimization, comprehensive studies were conducted on electrode composition, modification methods, electroanalytical parameters, and pH effects. The designed approach showed high sensitivity, stability, and reproducibility, with potential applicability in pharmaceutical preparations.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Georgios Bountas, Vlastimil Vyskocil, Bohumil Kratochvil, Alena Michalcova, Anastasios Economou, Jiri Barek
Summary: Nitrophenols are important environmental pollutants due to their genotoxic and ecotoxic properties. A novel silver porous electrode was successfully used for the determination of micromolar concentrations of 2-nitrophenol, 2,4-dinitrophenol, and 2,4,6-trinitrophenol.
Article
Chemistry, Analytical
Elena Alberto, Julio Bastos-Arrieta, Clara Perez-Rafols, Nuria Serrano, M. Silvia Diaz-Cruz, Jose Manuel Diaz-Cruz
Summary: A DPV method using SPCEs was developed for the determination of SMX, showing a good detection limit (15 μg/L) and a wide linear range (50-600 μg/L) with good repeatability and reproducibility. The method was successfully applied to the analysis of a spiked tap water sample, demonstrating high reproducibility and good trueness. Additional considerations were made on the pH-dependent electrochemical oxidation of SMX and the role of the free terminal amino group in oxidation.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Qianlu Zheng, Zachary A. H. Goodwin, Varun Gopalakrishnan, Alexis G. Hoane, Mengwei Han, Ruixian Zhang, Nathaniel Hawthorne, James D. Batteas, Andrew A. Gewirth, Rosa M. Espinosa-Marzal
Summary: This study investigates the influence of water on the performance of electrochemical devices using hydrophilic and hydrophobic ionic liquids as electrolytes. The results show that water uptake slightly reduces the electrochemical stability of ionic liquids and significantly affects the potential of zero charge of graphene. Hydrophilic ionic liquids efficiently screen surface charge, while hydrophobic ones are less efficient. Water uptake also leads to changes in the interfacial layering, which is important for the design of graphene-based electrochemical devices.
Article
Chemistry, Analytical
Hiroyuki Ueda, Soichiro Yoshimoto
Summary: This study systematically investigated the effect of the crystallographic orientation of gold on the interfacial processes of different ILs, showing that the cation and anion of the IL influenced the width of the EDL region and the Epw. Unique CV profile shapes were observed at each Au(hkl)|IL interface. Furthermore, surface-sensitive reductive desorption and re-adsorption of iodine adatoms on gold were observed, with the adsorption strength of [Cnmim]+ following a specific order on different gold orientations.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Vojtech Hrdlicka, Jiri Barek, Tomas Navratil
Summary: A novel method for determining the tumor marker homovanillic acid (HVA) in human urine was developed using a combination of HF-LPME and DPV techniques. The developed method was validated through optimization of conditions and standard addition method, showing accurate and reliable determination of HVA concentration.
Article
Chemistry, Analytical
Cem Erkmen, Gozde Aydogdu Tig, Bengi Uslu
Summary: A sandwich-type electrochemical aptasensor was developed for sensitive detection of leptin in biological samples. The synergistic effect of zinc oxide and gold nanoparticles improved the electrocatalytic activity, allowing for a wide linear concentration range and a low detection limit. The aptasensor demonstrated good selectivity, reproducibility, and stability, making it suitable for practical applications.
Article
Chemistry, Physical
Toni Y. Karlsson, Scott C. Middlemas, Manh-Thuong Nguyen, Michael E. Woods, Kevin R. Tolman, Vassiliki-Alexandra Glezakou, Steven D. Herrmann, Juliano Schorne-Pinto, Ryan D. Johnson, Shawn E. Reddish, Stephen A. Warmann, Patricia D. Paviet
Summary: There is currently a lack of knowledge and data on the thermophysical properties of fresh fuel salts containing plutonium. These properties are crucial for the future development of commercial molten-salt reactors. The study investigated the melting temperature, salt stability, density, and heat capacity of NaCl-PuCl3 salt mixtures. The results provided important insights for reactor design and licensing.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Analytical
Wen-Juan Wang, Xin-Yang Lu, Fen-Ying Kong, Heng-Ye Li, Zhong-Xia Wang, Wei Wang
Summary: In this study, rGO/Au-Bi nanocomposites were successfully synthesized and used for simultaneous electrochemical determination of Pb2+ and Cd2+. The results showed that under optimized conditions, the proposed electrode exhibited good linearity and low detection limits for Pb2+ and Cd2+. The electrode also demonstrated excellent resistance to interference, high stability, and good repeatability.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Yuval Simha, Gil Daniels, Amalya Goldman, Elihay Kuniavsky, Dmitry Tsvelikhovsky
Summary: A new strategy for direct access to fully substituted polycyclic imidazolium salts using alpha-enaminones and proline as the reagents is reported. This open-flask operation is a catalyst-, metal-, and Lewis acid-free green process, which does not require an ion-exchange step. It can produce good yields with minimal formation of side products, and is not limited to aryl substituents.
Article
Electrochemistry
Jenjira Saichanapan, Kiattisak Promsuwan, Kasrin Saisahas, Asamee Soleh, Kah Haw Chang, Ahmad Fahmi Lim Abdullah, Warakorn Limbut
Summary: The study used a glassy carbon electrode modified with hierarchical graphene oxide nanoplatelets to detect tramadol, finding that it had a faster charge transfer rate and larger active surface area compared to an electrode modified with graphene oxide nanosheets, increasing the anodic current response of tramadol. The sensor showed high sensitivity, low detection limit, good precision, and good anti-interference, with potential for tramadol detection.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2021)
Article
Chemistry, Applied
Cuizhong Zhang, Peican Chen, Liya Zhou, Jinyun Peng
Summary: A novel signal amplification strategy was designed in this study for high-sensitivity and -selectivity detection of 3,3',4,4'-tetrachlorobiphenyl. By optimizing the Schottky junction and sensitization, the response of the PEC aptasensor was successfully enhanced.
Article
Chemistry, Analytical
Jinyun Peng, Xueying Li, Yuxia Liu, Wenfeng Zhuge, Cuizhong Zhang, Yingying Huang
Summary: Developing materials with excellent photoelectric activity is essential for improving the sensitivity of photoelectrochemical sensors. In this study, a convenient method to synthesize phthalocyanine polymer dots has been reported, which were used to develop an ultrasensitive PEC sensor for dopamine detection. The sensor showed increased photocurrent intensity with higher concentrations of dopamine under blue light irradiation.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Nanoscience & Nanotechnology
Tianyu Wu, Ye Cao, Yansong Zhang, Zhaoting Zheng, Jing Li, Hongbo Li
Summary: The study developed a flexible and elegant plasmonic photothermal biosensing platform utilizing a bottom-up programmable and addressable DNA nanostructure, coupled with superparamagnetic nanostructure-aided entropy-driven DNA amplification networks and photostable Au-Ag hollow porous nanospheres. This method shows high sensitivity and stability in detecting progesterone, holding great potential for various applications.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Analytical
Cuizhong Zhang, Hongjie Liu, Wanting Nong, Jinyun Peng, Liwei Wang, Liya Zhou
Summary: A novel photoelectrochemical (PEC) aptasensor coupled with a Z-scheme was developed for the quantitative determination of sub-picogram per liter concentration of tetrachlorobiphenyl. The proposed method showed better photocatalytic activity and photo-to-current conversion efficiency without biased voltage. The PEC aptasensor demonstrated high sensitivity and specificity, making it a potentially valuable tool for detecting polychlorinated biphenyls in marine organisms.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Nanoscience & Nanotechnology
Gang Xiang, Xiansen He, Yuxia Liu, Qing Huang, Wei Huang, Cuizhong Zhang, Jinyun Peng
Summary: In this study, a novel CMP-rGO material was synthesized and used to construct a sensitive PEC sensor for detecting LDA. The sensor exhibited linear response and low detection limit under optimal experimental conditions, and showed good repeatability, stability, and selectivity. The sensor was successfully applied for detecting LDA in real samples.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Electrochemistry
Gang Xiang, Xiansen He, Yuxia Liu, Huan Lian, Cuizhong Zhang, Jinyun Peng
Summary: Dopamine (DA) plays a significant role in human physiology and pathology, making the rapid and sensitive detection of DA important. This study presents the synthesis of a novel quinoxaline-based conjugated microporous polymer (CMP) and the construction of a rapid and sensitive photoelectrochemical (PEC) sensor for DA detection. The developed PEC sensor demonstrates good detection ability, selectivity, and repeatability, with the capability to detect DA in blood serum.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
Article
Chemistry, Analytical
Jing Li, Yansong Zhang, Xin Wang, Shenlong Zhang, Qingqing Tan, Bingtao Hu, Qin Xu, Hongbo Li
Summary: A DNA/RNA biosensor capable of SNV resolution is proposed, which utilizes an entropy-driven nanomachine and coordination etching of Ag TNPs for visualization. The dual-modal (multicolorimetric and photothermal) biosensor shows noticeable color changes that can be differentiated by naked eye and accurate temperature reading. The programmable DNA nanotechnology and magnetic extraction grant the high specificity, and the dual-modal biosensor has the advantages of portability, cost-effectiveness, and simplicity.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Feng Shi, Maoying Peng, Haibing Zhu, Hongbo Li, Juan Li, Xiaoya Hu, Jingbin Zeng, Zhanjun Yang
Summary: This study proposes a functional zonation strategy for nanozymes to construct a multiple chemiluminescence imaging immunoassay. By dividing the Fe3O4-Au heterodimer nanozyme into two zones, the nanozyme zone and the antibody immobilization zone, a signal amplification probe is prepared for multiple antigens detection. The proposed method shows wide linear ranges and low detection limits with high sensitivity, high specificity, and good stability.
ANALYTICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Fengping Liu, Minghui Li, Jing Sun, Qiang Fang
Summary: In this paper, two fluorinated monomers (BCB-F and 2BCB-F) were designed and successfully prepared from biomass anethole, which were used to obtain low-k polymers with good comprehensive properties. Cured BCB-F exhibited a comparable dielectric constant and better hydrophobicity, while cured 2BCB-F showed excellent heat resistance and dielectric properties. Therefore, anethole-based polymers are suitable candidates for matrix or encapsulation resins in electronics and microelectric fields.
Article
Chemistry, Multidisciplinary
Qing Huang, Chen-dong Ling, Wen-feng Zhuge, Zeng-hu Zhang, Gang Xiang, Jin-yun Peng, Xue Liang
Summary: A novel PEC sensor was synthesized and used for the detection of environmentally harmful para-aminophenol (PAP). The sensor exhibited excellent sensitivity, selectivity, and stability. The proposed method provides an effective strategy for constructing PEC sensors to detect PAP in water samples.
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
(2023)
Article
Chemistry, Analytical
Gang Xiang, Xiansen He, Wenfeng Zhuge, Yuxia Liu, Cuizhong Zhang, Jinyun Peng
Summary: This paper reports the novel application of a synthesized quinoxaline-based conjugated microporous polymer-grafted graphene (CMP-rGO) in a photoelectrochemical (PEC) sensor for rifampicin (RIF) detection. The CMP-rGO-based PEC sensor exhibited good response to RIF with low detection limit, good repeatability, stability, and selectivity.
MICROCHEMICAL JOURNAL
(2023)
Article
Food Science & Technology
Gang Xiang, Wenzhuo Li, Qiuxiang Nong, Cuizhong Zhang, Zhengfa Zhang, Huan Lian, Jinyun Peng, Yufen Jiang, Yiqiu Tan, Jing Sun
Summary: Conjugated microporous polymers (CMPs) were used as a coating in solid-phase microextraction (SPME) to extract and enrich nine phthalate esters (PAEs) in various liquid samples. The method showed low LODs, wide linearities, good repeatability, and a long service life. Molecular docking analysis revealed the interaction model and binding energies between BQP-CMP and PAEs. This study demonstrates the excellent capability of BQP-CMP as a rapid and sensitive analysis material for PAEs at trace levels in different types of samples, highlighting the potential of CMP materials as SPME coatings.
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION
(2023)
Article
Chemistry, Analytical
Wei Huang, Fengping Liu, Gang Xiang, Zhenfa Zhang, Qing Huang, Zhenjie Pan, Wenfeng Zhuge, Jinyun Peng
Summary: Metal-organic frameworks (MOFs) consisting of metal ions and organic ligands have shown great potential in electrochemical sensors due to their high specific surface areas, controllable porous structures, and abundant metal active sites. In this study, a 3D conductive network structure (C-Co-N@MWCNTs) was developed by anchoring zeolite imidazole frameworks (ZIF-67) onto multi-walled carbon nanotubes (MWCNTs) and carbonizing them, which exhibited excellent electron conductivity, a porous structure, and considerable electrochemical active sites for the detection of adrenaline (Ad). The developed Ad sensor demonstrated high sensitivity and selectivity, with a low detection limit of 6.7 nmol L-1 (S/N = 3) and a wide linear range of 0.02 μmol L-1-1.0 mmol L-1. The C-Co-N@MWCNTs electrode also showed promising performance in detecting Ad in real human serum samples.
Article
Chemistry, Analytical
Gang Xiang, Wensi Xu, Wenfeng Zhuge, Qing Huang, Cuizhong Zhang, Jinyun Peng
Summary: A conductive phthalocyanine-based porous organic polymer (NiPc-CC POP) was synthesized and used as a conductive catalyst for electrochemical detection of Van with good performance.
Article
Chemistry, Analytical
Zhang Cui-Zhong, Lian Huan, Yang Wei, Zhuge Wen-Feng, Tang Xiao-Qian, Guo Yang-Yang, Peng Jin-Yun, Li Fu-Yan
Summary: Heavy metal pollution in environmental water systems poses a great threat to human health. In this study, a 3D mixed-aerogels with hierarchical porous structure was successfully synthesized by bonding carboxy carbon nanotubes and dialyzed graphene oxide, with polydopamine as the cross-linking agent. Bismuth nanoparticles were loaded in situ as the substrate to construct an electrochemical sensor for simultaneous detection of Pb2+ and Cd2+ with high accuracy and anti-interference properties.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).