Article
Biochemistry & Molecular Biology
Erika Kozma, Antonella Caterina Boccia, Anita Andicsova-Eckstein, Alfio Pulvirenti, Chiara Botta
Summary: The selective detection of metal ions in water using sustainable detection systems is crucial for monitoring water environments and ensuring drinking water safety. In this study, a low-cost, water-soluble potassium salt of PTAS was designed and synthesized, exhibiting a selective optical response to Cu2+ and Pb2+ ions in aqueous solutions. The use of a water-soluble chromophore and efficient analyte-probe interactions enabled sensitive detection of copper ions in drinking water and lead ions in waste water, providing a basis for sustainable sensing systems.
Article
Chemistry, Inorganic & Nuclear
Ipek Omeroglu, Sureyya Oguz Tumay, Saad Makhseed, Ali Husain, Mahmut Durmus
Summary: The synthesis of a new resorcin [4]arene cavitand 3 with multiple BODIPY sites was achieved using Cu-catalyzed azide-alkyne cycloaddition (CuAAC), and its structure was characterized using various analytical techniques. This molecular system can serve as an optical sensor for various metal cations, showing a significant decrease in fluorescence emission towards Cu(II) ions and an increase in response towards triazole fungicides, making it feasible as a dual optical sensor for detecting heavy metals and pesticides.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Organic
Rajesh Sahu, Saurav Yadav, Krishna Chaitanya Gunturu, Anant R. Kapdi
Summary: Sensing important metals in different environments is vital, and the use of fluorescent sensors in metal sensing is a widely applied method. This study introduces a phenothiazine-based fluorescent sensor for Cu(II) ions, which shows high selectivity compared to other transition metal salts. The Lewis acidity of the Cu(II) salt and a 1:1 ratio were found to enhance the sensing response in MeOH solvent.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Analytical
Rasha M. Kamel, Ahmed Shahat, Aly H. Atta, Mohamed M. A. Farag-Allah
Summary: The study created an optical, chemical sensor using mesoporous silica surface for colorimetric recognition of Cu(II) and Pd(II) ions with high sensitivity. The sensor was characterized and modeled for adsorption efficiency, showing effective detection and extraction of target ions from E-wastes.
MICROCHEMICAL JOURNAL
(2022)
Article
Biochemical Research Methods
Danqun Huo, Ya Zhang, Ning Li, Wenhao Ma, Huan Liu, Guoren Xu, Zhihua Li, Mei Yang, Changjun Hou
Summary: In this study, an innovative electrochemical sensor was developed for simultaneous detection of heavy metal ions Cd2+, Hg2+, Cu2+, and Pb2+. The sensor, which used a screen-printed electrode modified with 3DGO and UiO-66-NH2 composite nanomaterials, could conveniently, sensitively, and reliably detect trace amounts of heavy metal ions in food within 150 seconds.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Environmental
Lili He, Kuixing Ding, Jia Luo, Qinxiang Li, Jun Tan, Jiugang Hu
Summary: A novel surface-enhanced Raman scattering (SERS)-active catcher was designed for rapid and selective detection of heavy metal ions. The hydrophobic hydroxyoxime-mediated plasmonic silver membrane showed excellent SERS activity, high reproducibility, and long-term stability. This new platform demonstrated fast, dry-free, and selective detection of Cu(II) ions, with a low detection limit.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Physical
Mengyu Pei, Hanhan Kong, Anqi Tian, Xiang Liu, Kaibo Zheng, Zhilin Ren, Long Wang
Summary: A new fluorescent probe system was constructed by amino derivatization reaction, which can selectively obtain different kinds of probes for the detection of Cu2+ ion. The probes have low detection limit, high selectivity, and can sensitively detect the presence of Cu2+ ion.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Materials Science, Multidisciplinary
Xieraili Maimaitiyiming, Caijin Shi
Summary: A series of alternating conjugated polymers were synthesized via Sonogashira coupled reaction, showing high specificity and sensitivity towards I- and Hg2+, making them suitable for optical probe applications.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Chemistry, Analytical
Jem-Kun Chen, Xiang-Yun Zeng, Chih-Chia Cheng, Chih-Wei Chen
Summary: The hydrophobic atom-transfer radical polymerization (ATRP) initiator formed ring patterns at the interface after being wetted with oxygen plasma. The rings were then converted to polyvinyltetrazole (PVT) rings, which could adsorb Cu(II). The localized surface plasmon resonance (LSPR) peak showed a blue-shift as Cu(II) was adsorbed by the PVT rings.
Article
Engineering, Environmental
J. Mejia Avila, M. Rangel Ayala, Y. Kumar, E. Perez-Tijerina, Mitchel A. R. Robles, V Agarwal
Summary: Sustainable, scalable, and green carbon dots derived from avocado seeds were used as fluorescent nanoprobes for the detection of heavy metal ions. The carbonization temperature affected the size, crystallinity, and sensitivity of the carbon dots towards Cu2+ and Cr6+ ions.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Geochemistry & Geophysics
Shane R. Cloude
Summary: The letter introduces a new algorithm for object detection in unwanted background signal using polarimetric response measurement, with examples provided for radar ship detection and aerosol particle discrimination in optics.
IEEE GEOSCIENCE AND REMOTE SENSING LETTERS
(2021)
Article
Chemistry, Analytical
Yanyan Niu, Yuxue Chen, Xiaoping Zhang, Hui Xie, Guiling Luo, Wei Sun
Summary: This study developed a PEC aptasensor for quantitative analysis of Cd(II) by changing the sensing interface structure to amplify the detection signal. The sensor showed high sensitivity with a detection limit of 1.1 x 10-11 mol/L and was successfully used for water sample detection.
MICROCHEMICAL JOURNAL
(2021)
Article
Environmental Sciences
Pegah Parizadeh, Farid Moeinpour, Fatemeh S. Mohseni-Shahri
Summary: A green and effective metallochromic sensor was developed using anthocyanin extract from black eggplant peels embedded in bacterial cellulose nanofibers. The sensor can detect copper ions in solution and solid state, with quantification limits of 10-400 ppm and 20-300 ppm respectively. It can produce a visual color change from brown to light blue and dark blue depending on the copper concentration in aqueous matrices.
Article
Chemistry, Applied
Yu Zhang, Liang Zhang, Ruohui Gao, Lvling Zhong, Juanqin Xue
Summary: The polymer composite material PVA/BC/CaCO3 was developed for selective adsorption of toxic heavy metal ions such as Cd(II), Cu(II), and Pb(II) from solution. The adsorption kinetics data fit the pseudo-first-order kinetics model, while the thermodynamic adsorption data fit the Langmuir model. The maximum adsorption capacities for Cu(II), Pb(II), and Cd(II) were found to be 57.1, 513.6, and 238.6 mg/g, respectively, at 40 degrees C. This adsorbent also showed high recyclability, indicating its potential in removing heavy metal ions from contaminated solutions.
CARBOHYDRATE POLYMERS
(2021)
Article
Engineering, Environmental
Jianying Wu, Jing Zou, Jinbin Lin, Sheng Li, Siying Chen, Xiaobin Liao, Jingxin Yang, Baoling Yuan, Jun Ma
Summary: This study proposed an effective strategy to enhance the oxidative capacity of the Cu(II)/PAA system by adding hydroxylamine (HA), which facilitates the redox cycle of Cu(I)/Cu(II). The HA/Cu(II)/PAA system showed a significantly improved removal rate of diclofenac, with a broad pH range of 4.5-9.5. It also exhibited a strong anti-interference ability towards commonly existent water matrix.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Materials Science, Ceramics
Sumaya H. Almenia, Adel A. Ismail, Khalid A. Alzahrani, Mutlaq Aljahdali
Summary: The synthesis and design of heterojunction nanocomposites with remarkable photocatalytic performance remain a challenge. In this work, CuMn2O4/Co3O4 nanocomposite heterojunctions were fabricated using a sol-gel strategy with soft template assistance. The CuMn2O4/Co3O4 nanocomposites exhibited significant enhancement in degradation efficiency and achieved 100% degradation of tetracycline within 75 min. The enhanced photocatalytic ability was attributed to the construction of heterojunction, synergistic effect between CuMn2O4 and Co3O4, enlarged surface area, strengthened effective charge mobility, and narrowed bandgap energy.
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Physical
Khalid A. Alzahrani, Adel A. Ismail
Summary: CuMn2O4/BaSnO3 nanocomposites fabricated by hydrothermal approach exhibited superb photocatalytic performance for Ciprofloxacin degradation under visible light illumination.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Engineering, Chemical
Khalid A. Alzahrani, Adel A. Ismail, Nadiyah Alahmadi
Summary: The researchers constructed CuMn2O4/CeO2 heterojunction nanocomposites using a facile sol-gel method and evaluated their photocatalytic hydrogen evolution performance compared to pure CeO2 NPs under visible light. It was found that the H2 evolution rate of 15%CuMn2O4/CeO2 photocatalyst was five times higher than that of pure CeO2, attributed to its higher electron transport ability and electron-hole separation efficiency.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2023)
Article
Engineering, Chemical
Adel A. Ismail, L. Al-Hajji, I. S. Azad, A. Al-Yaqoot, N. Habibi, M. Alseidi, Sh. Ahmed
Summary: The study found that the Ag/TiO2 films coated with silver nanoparticles exhibited excellent antibacterial properties, with the best inhibitory effect on Vibrio parahaemolyticus, Aeromonas hydrophila, and Bacillus subtilis. Exposing the films to direct light for 3 hours was sufficient to reduce the bacterial counts. The higher antibacterial activity of Ag/TiO2, Ag/ZnO, and Ag/Fe2O3 films compared to pristine ZnO, Fe2O3, and TiO2 films might be attributed to the surface plasmon resonance of Ag nanoparticles, which facilitated the separation of charge carriers and enhanced the antibacterial activity.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2023)
Article
Chemistry, Multidisciplinary
Mohamed S. Selim, Nesreen A. Fatthallah, Mohamed A. Shenashen, Shimaa A. Higazy, Hekmat R. Madian, Mahmoud M. Selim, Sherif A. El-Safty
Summary: A catalytic hydrosilation approach was used to construct a bio-inspired porous nanocoating with micro-/nano-roughness, low surface free energy, and high fouling release efficiency. The coating showed simplicity in fabrication, ease of large-area preparation, and the ability to simultaneously offer dual micro-/nano-scale structures. This study may expand the applications of bio-inspired functional materials.
Article
Materials Science, Multidisciplinary
Ibraheem A. Mkhalid, Adel A. Ismail, Mahmoud A. Hussein, Raed H. M. Al Thomali
Summary: In this study, mesoporous V2O5-TiO2 heterojunctions were synthesized using a soft-chemistry method and evaluated for their photocatalytic performance in the degradation of tetracycline under visible light exposure. The V2O5-TiO2 nanocomposites showed higher photocatalytic activity compared to bare TiO2 and P-25, due to their enhanced visible light absorption ability, larger surface area, and improved carrier separation efficiency. The designed heterojunctions of V2O5-TiO2 nanocomposites effectively reduced the recombination rate of photoinduced carriers, resulting in enhanced photocatalytic performance.
Review
Materials Science, Multidisciplinary
Ahmed Elmasry, Wiyao Azoti, Sherif A. El-Safty, Ahmed Elmarakbi
Summary: This article discusses the importance of modeling and simulation in the materials industry, the application of multiscale techniques in studying composite materials, and the criteria for selecting appropriate models.
PROGRESS IN MATERIALS SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Khalid Althumayri, Ahlem Guesmi, Wesam Abd El-Fattah, Ammar Houas, Naoufel Ben Hamadi, Ahmed Shahat
Summary: This study successfully synthesized a nanocomposite adsorbent based on mesoporous silica nanotubes (MSNTs) loaded with 3-aminopropyltriethoxysilane (3-APTES@MSNTs), which was employed for the adsorption of tetracycline (TC) antibiotics. The nanocomposite exhibited a maximal TC adsorption capability of 848.80 mg/g. The characterization results revealed that the 3-APTES@MSNT nanoadsorbent possessed abundant surface functional groups, an effective pore size distribution, a larger pore volume, and a relatively higher surface area.
Article
Chemistry, Physical
Eslam Talaat, Mohammed Y. Emran, Hassanien Gomaa, Ahmed Kotb, Adel A. Abdelwahab, Mohamed Abdel-Hakim, Eman M. Saad, Mohamed. A. Shenashen, Sherif A. El-Safty
Summary: An active electrochemical sensor for screening adrenaline (AD) in human fluid samples and pharmaceutical drugs was developed using sulfur-doped carbon microspheres (S-CMS) and irregular-edge carbon stacked sheet (S-CSS) structures. The S-CSS-based sensor exhibited high selectivity and sensitivity with a wide detection range and a low detection limit for AD. It can be used to monitor AD in pharmaceutical drugs and human blood serum with fast response and using highly economic materials at extremely low concentrations.
SURFACES AND INTERFACES
(2023)
Article
Engineering, Environmental
Hassanien Gomaa, Mohamed A. Shenashen, Mohamed F. Cheira, Keisuke Sueki, Tarek A. Seaf El-Nasr, Mahmoud M. Selim, Sherif A. El-Safty
Summary: This study proposes an efficient method for extracting uranium from raw materials by utilizing Three-dimensional mesoporous silica monoliths (MSMs) derived from affordable and sustainable resources like rice husk. The MSMs exhibit high selectivity in extracting 238U isotopes from altered granite rock.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Green & Sustainable Science & Technology
Hassanien Gomaa, Mohamed A. Shenashen, Mohamed F. Cheira, Keisuke Sueki, Tarek A. Seaf El-Nasr, Mahmoud M. Selim, Sherif A. El-Safty
Summary: The expansion of engineering and development of porous materials from agro-waste-derived for the synthesis of bio-adsorbents as efficient extractors is a significant breakthrough in the economy and environment. This study successfully prepared a novel spongy mesoporous hybrid silica (SMS-L) from wheat straw through dissolution/precipitation methodology. The SMS and SMS-L bio-adsorbents were used to extract/preconcentrate 232Th isotope from Egyptian cataclastic rock (ECR), showing high adsorption capacity depending on the pH value of the extraction process. The research provides important insights into the utilization of sustainable waste and the potential for clean energy applications.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Chemistry, Multidisciplinary
Khalid Althumayri, Ahlem Guesmi, Wesam Abd El-Fattah, Lotfi Khezami, Taoufik Soltani, Naoufel Ben Hamadi, Ahmed Shahat
Summary: The aim of this study was to assess the efficiency of mesoporous silica nanospheres as an adsorbent for removing doxorubicin (DOX) from water. The surface and structural properties of mesoporous silica nanospheres were analyzed using various techniques. A Box-Behnken surface statistical design and response surface modeling were used to optimize the removal of DOX. Under specific conditions, a high adsorptivity of DOX was achieved, and the Langmuir equation matched well with the experimental data. The adsorption of DOX on mesoporous silica nanospheres was found to be endothermic, spontaneous, and best described by the pseudo-second-order model.
Article
Chemistry, Multidisciplinary
Huda Salem AlSalem, Faisal K. Algethami, Soha Talal Al-Goul, Ahmed Shahat
Summary: In this study, a novel and efficient method called dispersive solid-phase extraction based on functionalized mesoporous silica nanotubes (FMSNT nanoadsorbent) was developed to remove tetrabromobisphenol A (TBBPA) from water samples. The characterization and comprehensive analysis of the FMSNT nanoadsorbent confirmed its potential, including a maximum adsorption capacity of 815.85 mg g(-1) for TBBPA and its water stability. The results revealed the influence of various factors on the adsorption process, such as pH, concentration, dose, ionic strength, time, and temperature.
Article
Materials Science, Multidisciplinary
Ibraheem A. Mkhalid, Adel A. Ismail, Mahmoud A. Hussein, Raed H. M. Al Thomali
Summary: Novel MnCo2O4 nanoparticles (NPs) supported on porous TiO2 networks were prepared for tetracycline (TC) degradation. The photocatalytic activity of the MnCo2O4/TiO2 nanocomposite was significantly higher than that of TiO2 NPs and P-25, with a degradation rate of 100% within 60 minutes.
MATERIALS RESEARCH BULLETIN
(2023)
Article
Chemistry, Physical
Wesam Abd El-Fattah, Ahlem Guesmi, Naoufel Ben Hamadi, Mohamed. G. El-Desouky, Ahmed Shahat
Summary: A novel cellulose nanocrystals biosorbent (CNCs) was synthesized and characterized for the efficient removal of indigo carmine blue (ICB) dye from wastewater. The study examined the adsorption behavior of ICB on CNCs under various reaction parameters. The results showed that CNCs exhibited a high adsorption capacity and chemisorption behavior towards ICB. Furthermore, CNCs demonstrated excellent reusability after multiple cycles of adsorption.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).