Article
Agricultural Engineering
Yufang Wei, Zipei Li, Wenjuan Ran, Hairong Yuan, Xiujin Li
Summary: This study found that by combining KOH or LFD modifications with trace element supplementation, the biomethane yield of anaerobic co-digestion can be significantly increased. Changes in microbial community at the genus level can affect the main digestion pathways, ultimately influencing co-digestion performance.
BIORESOURCE TECHNOLOGY
(2021)
Article
Nutrition & Dietetics
Piotr Bawiec, Jan Sawicki, Paulina Lasinska-Pracuta, Marcin Czop, Ireneusz Sowa, Katarzyna Ilowiecka, Wojciech Koch
Summary: Bioavailability refers to the fraction of a substance that is absorbed from the gastrointestinal tract and enters the bloodstream. This study aimed to assess the bioavailability of selenium (Se) from dietary supplements and explore the influence of diet type on relative bioavailability. The research used a two-stage in vitro digestion model to simulate the digestion of food containing dietary supplements. Selenium bioavailability ranged from 19.31% to 66.10% in the presence of food matrix. Sodium selenate had the highest bioavailability, followed by organic forms and sodium selenite. The basic diet with moderate protein and high carbohydrate and fiber content positively influenced Se bioavailability. The pharmaceutical form of the product also affected bioavailability, with tablets having the highest bioavailability, followed by capsules and coated tablets.
Article
Agricultural Engineering
Xianpu Zhu, Dominic Yellezuome, Ronghou Liu, Zengzhen Wang, Xin Liu
Summary: This study found that co-digestion of food waste, corn straw, and chicken manure in group A of two-stage anaerobic digestion resulted in higher hydrogen and methane production efficiency, as well as a higher bioavailability of trace elements within a wider range. Increased abundance of hydrogenotrophic methanogens reflected improved efficiency in two-stage methane co-digestion.
BIORESOURCE TECHNOLOGY
(2022)
Review
Food Science & Technology
Wanrong Zhao, Vigasini Subbiah, Cundong Xie, Zihong Yang, Linghong Shi, Colin Barrow, Frank Dunshea, Hafiz A. R. Suleria
Summary: Seaweeds, rich in phenolic compounds, possess antioxidant, antibacterial, and anti-inflammatory activities. However, these polyphenols have low oral bioaccessibility and bioavailability due to extensive modifications in the digestive tract and are greatly influenced by factors such as food matrix, food processing methods, and host factors.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Agricultural Engineering
Yafan Cai, Leandro Janke, Xingyao Meng, Zehui Zheng, Xiaoling Zhao, Juergen Proeter, Franziska Schaefer
Summary: This study investigated the bioavailability of trace elements (TEs) and the effect of supplementation on anaerobic digestion of chicken manure leachate. The results showed low bioavailability of certain TEs, but supplementation improved their bioavailability and methane production efficiency. Scrutinizing the bioavailability and absolute concentrations of available TEs is critical for assessing the risk of TEs deficiency.
BIORESOURCE TECHNOLOGY
(2022)
Review
Green & Sustainable Science & Technology
Mohammad Javad Bardi, Sergi Vinardell, Sergi Astals, Konrad Koch
Summary: The opportunities and challenges of applying micronutrients in full-scale anaerobic digestion plants are reviewed. The bioavailability of micronutrients is a key factor affecting their effectiveness. Co-supplementation can increase bioavailability and have synergistic effects on AD performance. However, inconsistent lab-scale results and the lack of guidelines for analyzing bioavailability limit full-scale application.
RENEWABLE & SUSTAINABLE ENERGY REVIEWS
(2023)
Article
Environmental Sciences
Taylor R. Alvarado, Andrew C. Lee, Bryan Tomlin, Paul Schwab
Summary: This study aimed to evaluate commonly used internal standards (ISs) in inductively coupled plasma-mass spectrometry (ICP-MS) and develop a protocol for evaluation. The results showed that In-115 was the most consistent IS, but it is necessary to screen soils prior to analysis to avoid interference from naturally occurring concentrations.
JOURNAL OF ENVIRONMENTAL QUALITY
(2022)
Article
Multidisciplinary Sciences
Bikash Chandra Maharaj, Maria Rosaria Mattei, Luigi Frunzo, Eric D. van Hullebusch, Giovanni Esposito
Summary: This study proposes a method to assess the bioavailability of trace elements in anaerobic digestion systems using a mathematical model, and predicts the impact of different factors on TE speciation through numerical simulations. Experimental data comparison confirms the applicability of this modeling framework to various anaerobic digestion operations.
SCIENTIFIC REPORTS
(2021)
Article
Food Science & Technology
Mikolaj Antoni Gralak, Iwona Lasocka, Maria Leontowicz, Hanna Leontowicz, Piotr Latocha, Shela Gorinstein
Summary: This study aimed to investigate the influence of different cultivars of Actinidia arguta on the bioavailability of mineral elements and the mineral profile of rats fed atherogenic diets enriched with kiwiberries. The results showed that the addition of kiwiberries in the diet increased the liver iron content but decreased the bioavailability of manganese, zinc, and copper. This effect may be related to the bioactive compounds present in kiwiberries.
Article
Agronomy
Jelena Maksimovic, Radmila Pivic, Aleksandra Stanojkovic-Sebic, Marina Jovkovic, Darko Jaramaz, Zoran Dinic
Summary: This study aimed to examine the possibility of improving the prediction of bioavailability of trace elements by using a different strategy of model development. Results indicated that forming a testing set based on soil type yields models with more reliable predictions than the basic ones. To enhance the performance of prediction models, it is necessary to include additional physicochemical parameters and conduct comprehensive statistical analysis with extensive testing sets.
Article
Environmental Sciences
Hamed Baniamerian, Parisa Ghofrani-Isfahani, Panagiotis Tsapekos, Merlin Alvarado-Morales, Mohammad Shahrokhi, Irini Angelidaki
Summary: The study found that metals such as nickel and iron are crucial for the anaerobic digestion process, and utilizing nickel and iron coated on TiO2 nanoparticles can enhance hydrolysis rate and methane production of substrates.
Review
Food Science & Technology
Sebastien Marze
Summary: This article investigates the kinetics of lipid digestion and bioavailability and their impact on various diseases. The study finds a close link between lipid digestion kinetics and bioavailability kinetics, which can be modulated through food design or combination. The article presents different approaches, such as in vitro, modeling, in vivo, and mixed methods, to study the kinetics of both processes. It also proposes a unifying modeling scheme to better understand the role and interactions of various factors involved in lipid metabolism.
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Food Science & Technology
Michelle Goncalves Santana, Otniel Freitas-Silva, Lilian Regina Barros Mariutti, Anderson Junger Teodoro
Summary: International guidelines strongly recommend the frequent consumption of plant-based foods, especially fruits, due to their abundant bioactive substances. Assessing the bioaccessibility of polyphenols in tropical fruits is crucial, and various methods are used for this purpose. While standardized in vitro digestion methods exist, there is limited research on using these methods to evaluate the bioaccessibility of polyphenols in tropical fruits.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Agriculture, Multidisciplinary
Shan Ahamed Tharifkhan, Anand Babu Perumal, Arunkumar Elumalai, Jeyan Arthur Moses, Chinnaswamy Anandharamakrishnan
Summary: Millets are traditional staple foods in dryland regions, rich in essential nutrients but also containing anti-nutritional factors that may reduce bioavailability. Methods such as soaking, germination, and autoclaving can reduce these factors and enhance nutrient bioavailability.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Chemistry, Applied
Nanbing Qin, Asta H. Petursdottir, David J. Humphries, Natasa Desnica, Eric E. Newton, Aila Vanhatalo, Anni Halmemies-Beauchet-Filleau, Luke Bell, D. Ian Givens, Darren T. Juniper, Helga Gunnlaugsdottir, Sokratis Stergiadis
Summary: Seaweed supplement can increase milk iodine content, but care should be taken to avoid excessive levels that may pose nutritional risks for young children.
Article
Chemistry, Analytical
Cristian Suarez-Oubina, Ivan Alvarez-Freire, Pamela Cabarcos, Ana Maria Bermejo, Pilar Bermejo-Barrera, Antonio Moreda-Pineiro
Summary: The global market for new psychoactive substances (NPSs) is expanding, and the availability of drugs is increasing. Synthetic cannabinoids (SCRAs) are the largest group of NPSs and are often overlooked in illegal drug market control and toxicological-forensic analysis. Membrane-assisted solvent extraction (MASE) has been proposed as a method for extracting SCRAs from urine samples. The method was validated and found to be selective and sensitive, with low limits of quantification (LOQs).
ANALYTICAL METHODS
(2023)
Article
Biochemical Research Methods
Cristian Suarez-Oubina, Paloma Herbello-Hermelo, Natalia Mallo, Maria Vazquez, Santiago Cabaleiro, Ivone Pinheiro, Laura Rodriguez-Lorenzo, Begona Espina, Pilar Bermejo-Barrera, Antonio Moreda-Pineiro
Summary: This research focuses on using single-cell inductively coupled plasma-mass spectrometry (scICP-MS) to assess the associations of titanium dioxide nanoparticles (TiO2 NP) and silver nanoparticles (Ag NP) in cell lines derived from aquaculture species. The optimization studies aim to avoid high dissolved background, multi-cell peak coincidence, and possible spectral interferences. The results show that TiO2 NPs mainly interact with the outer cell membranes, while Ag NPs can enter the cells.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Environmental
Elza Fonseca, Maria Vazquez, Laura Rodriguez-Lorenzo, Natalia Mallo, Ivone Pinheiro, Maria Ligia Sousa, Santiago Cabaleiro, Monica Quarato, Miguel Spuch-Calvar, Miguel A. Correa-Duarte, Juan Jose Lopez-Mayan, Mick Mackey, Antonio Moreda, Vitor Vasconcelos, Begona Espina, Alexandre Campos, Mario Jorge Araujo
Summary: In this study, the effects of citrate-coated TiO2 nanoparticles (TiO2 NPs) of two different primary sizes on the liver of flatfish turbot were investigated. The results showed that the abundance of lipid droplets in hepatocytes varied depending on the size of TiO2 NPs, with an increase in turbot exposed to smaller NPs and a depletion with larger NPs. Gene expression related to oxidative and immune responses as well as lipid metabolism was also influenced by TiO2 NPs. These findings emphasize the importance of scrutinizing the risks associated with exposure to NPs with distinct properties in aquatic organisms.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Analytical
Cristian Suarez-Oubina, Pamela Cabarcos-Fernandez, Maria Jesus Tabernero-Duque, Pilar Bermejo-Barrera, Antonio Moreda-Pineiro, Ana Maria Bermejo-Barrera
Summary: Using ultrasounds, the extraction time for membrane-assisted solvent extraction (MASE) in isolating synthetic cathinones from urine has been shortened to 30 minutes. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used for the separation and determination of eleven synthetic cathinones. The developed method showed efficient extraction and pre-concentration of synthetic cathinones with LogP values higher than 2.0.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Juan Jose Lopez-Mayan, Blanca Alvarez-Fernandez, Elena Pena-Vazquez, Maria Carmen Barciela-Alonso, Antonio Moreda-Pineiro, Julie Maguire, Mick Mackey, Monica Quarato, Ivone Pinheiro, Begona Espina, Laura Rodriguez-Lorenzo, Pilar Bermejo-Barrera
Summary: A study was conducted to investigate the bioaccumulation of citrate-coated titanium dioxide nanoparticles in red (Palmaria palmata) and green (Ulva sp.) seaweed. The results showed that Ulva sp. had higher titanium concentrations than Palmaria palmata under the same exposure conditions. The titanium concentration in Ulva sp. reached its maximum after 28 days of exposure to 1.0 mgL(-1) of 5 nm TiO(2)NPs. The sizes and concentrations of TiO(2)NPs determined by SP-ICP-MS were similar for both seaweeds, suggesting that the titanium is mainly accumulated in Ulva sp. as ionic titanium or nanoparticles smaller than the limit of detection in size.
Article
Chemistry, Analytical
Cristian Suarez-Oubina, Annarosa Mangone, Lorena C. C. Giannossa, Laura Nunez-Gonzalez, Paloma Herbello-Hermelo, Pilar Bermejo-Barrera, Antonio Moreda-Pineiro
Summary: Imaging studies using laser ablation-inductively coupled plasma mass spectrometry were conducted to analyze the presence and distribution of titanium (ionic titanium and/or titanium dioxide nanoparticles) in sea bream tissues after exposure to citrate-coated titanium dioxide nanoparticles. Calibration based on gelatine standards containing ionic titanium was used, and good repeatability and linearity of measurements were achieved. The optimized conditions resulted in a limit of detection of 0.087 μg g(-1) titanium.
Article
Chemistry, Multidisciplinary
Ivone Pinheiro, Monica Quarato, Antonio Moreda-Pineiro, Ana Vieira, Virginie Serin, David Neumeyer, Nicolas Ratel-Ramond, Sebastien Joulie, Alain Claverie, Miguel Spuch-Calvar, Miguel A. Correa-Duarte, Alexandre Campos, Jose Carlos Martins, Pilar Bermejo-Barrera, Marisa P. Sarria, Laura Rodriguez-Lorenzo, Begona Espina
Summary: Commercial ATO nanoparticles are relatively harmless to zebrafish and marine mussels, but they do affect the developmental parameters of zebrafish. Further research is needed on the accumulation of nanoparticles in the human body.
Article
Chemistry, Analytical
I. Alvarez-Freire, P. Cabarcos-Fernandez, N. C. Rubio, A. Moreda-Pineiro, M. J. Tabernero-Duque, I. Sanchez-Sellero, P. Bermejo-Barrera, A. M. Bermejo-Barrera
Summary: Hygrine and cuscohygrine have been proposed as markers for differentiating legal and illegal cocaine consumption. However, analytical methods for assessing coca leaf alkaloids in oral fluid are lacking in forensic toxicology laboratories worldwide. This study aims to optimize a separation method using solid-phase extraction coupled with liquid chromatography-tandem mass spectrometry, resulting in improved detection and quantification limits for coca leaf alkaloids.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
