Article
Materials Science, Multidisciplinary
Panpan Chen, Zhenjie Zhao, Guangchen Zhang, Xiao Jin, Li-Min Wang, Ying Dan Liu
Summary: This study demonstrates the significant influence of the dosage of ILs on the morphology and electrorheological effects of silica-based ionogels. A proper amount of ILs can enhance the ER effects of ionogels, while excessive ILs may reduce the ER effect.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Chemistry, Analytical
Vincent Pellas, Fadoua Sallem, Juliette Blanchard, Antoine Miche, Sara Martinez Concheso, Christophe Methivier, Michele Salmain, Souhir Boujday
Summary: This article introduces the engineering of nanobiosensors made from gold nanorods coated with an ultrathin layer of silica and biofunctionalized with antibodies. The use of gold nanorods for biosensing is limited due to the presence of a surfactant that complicates their bio-functionalization. However, when coated with a thin layer of silica, these nanomaterials exhibit improved sensitivity and analytical performances.
Article
Chemistry, Multidisciplinary
Jessi E. S. van der Hoeven, Harith Gurunarayanan, Maarten Bransen, D. A. Matthijs de Winter, Petra E. de Jongh, Alfons van Blaaderen
Summary: The study introduces a new type of functional assembly called supraparticles, which are formed by the solvent-driven assembly of silica-coated gold nanorods into spherical ensembles. The plasmonic coupling and mass transport are controlled by adjusting the thickness and porosity of the silica shells. These novel materials have the potential to play an important role in sensing applications.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Yi-Ge Feng, Xiao-Yu Wang, Zhi-Wu Wang, Ai-Jun Wang, Li-Ping Mei, Xiliang Luo, Jiu-Ju Feng
Summary: Using porous nanomaterials as nanocarriers for immobilization and signal amplification of the probes, a label-free electrochemical immunosensor was efficiently designed for ultrasensitive detection of PCT. The immunosensor exhibited a good linear relationship and an ultra-low limit of detection.
BIOELECTROCHEMISTRY
(2021)
Article
Engineering, Electrical & Electronic
Anifatul Faricha, Parthojit Chakraborty, Keisuke Okamoto, Tso-Fu Mark Chang, Masato Sone, Takamichi Nakamoto
Summary: In this study, a sensor array system was developed to enhance the separation of biobutanol isomers using different sensing films and electrolytes. Reproducibility and concentration dependency of the sensors were also investigated.
IEEE SENSORS JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Qianqian Duan, Min Yang, Boye Zhang, Yi Li, Yixia Zhang, Xiaoning Li, Jianming Wang, Wendong Zhang, Shengbo Sang
Summary: By coating silica shell and gold nanocluster on the outer layer of gold nanorods, a novel nanocomposite with superior photothermal effect was developed, showing great potential in imaging guided photothermal therapy for cancer.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Jintao Zhang, Jinchang Yin, Ruiran Lai, Yue Wang, Baorui Mao, Haonan Wu, Li Tian, Yuanzhi Shao
Summary: In this study, machine learning was used to predict the coating process of silica on gold nanorods with different preparation parameters, and the results were validated through experiments. High-throughput predictions led to the identification of optimal process parameters for the preparation of high-quality silica-coated gold nanorods. The study demonstrates the potential of combining machine learning algorithms with experiments to predict, optimize, and accelerate the preparation of core-shell inorganic materials, and can be extended to other nanomaterial research.
Article
Materials Science, Multidisciplinary
Yarden Melamed, Nabasmita Maity, Louisa Meshi, Noam Eliaz
Summary: Electrodeposition of pure aluminum on copper and nickel substrates from an ionic liquid at room temperature was successfully achieved, resulting in dense and homogeneous aluminum deposits with nanocrystalline structure. The process exhibited a quasi-reversible reaction with current affected by both charge transfer and mass transport. Additionally, the deposition rate and grain size could be significantly improved by adjusting the applied cathodic potential.
Article
Nanoscience & Nanotechnology
Pranjyan Dash, Senthilkumar Thirumurugan, Ching-Li Tseng, Yu-Chien Lin, Sung-Lung Chen, Udesh Dhawan, Ren-Jei Chung
Summary: This study developed dumbbell-shaped nanocomposites consisting of titanium dioxide/gold nanorods coated with mesoporous silica shells. Methotrexate was loaded onto the nanocomposites and upconversion nanoparticles were decorated to enhance the therapeutic effects. In vitro and in vivo experiments demonstrated the synergistic photodynamic therapy, photothermal therapy, and chemotherapy effects of the nanocomposites, making them a promising candidate for cancer treatment using near-infrared light.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Isabela Barreto da Costa Januario Meireles, Marcelo Fernando Cipreste, Pedro Lana Gastelois, Waldemar Augusto de Almeida Macedo, Dawidson Assis Gomes, Edesia Martins Barros de Sousa
Summary: Gold nanoparticles, especially gold nanorods, are widely used in biomedical applications due to their unique optical properties. Silica-coated gold nanorods show good stability, morphology, and biocompatibility in photothermal therapy, making them a promising therapeutic agent.
Article
Chemistry, Physical
Pablo A. Mercada, Luis A. Perez, Eduardo A. Coronado
Summary: The study focused on determining the porosity degree of the m-SiO2 shell of GNRs@m-SiO2 at different concentrations of the porogenic surfactant CTAB by analyzing the extinction spectra features and using electrodynamics modeling. Changes in CTAB concentration affect both the porosity and thickness of the m-SiO2 shell.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Physical
Xiaolu Zhuo, David Vila-Liarte, Shengyan Wang, Dorleta Jimenez de Aberasturi, Luis M. Liz-Marzan
Summary: A study on the stability of chiral gold nanorods (Au NRs) covered by different protecting shells was conducted. The findings can be applied to other chiral plasmonic nanoparticles and address concerns of instability in various applications.
CHEMISTRY OF MATERIALS
(2023)
Article
Chemistry, Applied
Fereshteh Koosha, Zohreh Jomeh Farsangi, Hadi Samadian, Seyed Mohammad Amini
Summary: The development of theranostic nanostructures is a rapidly advancing field in pharmaceutical and medical sciences. Gold nanostructures, with unique properties, are of particular interest to researchers. Coating these nanostructures with mesoporous silica can enhance thermal stability and drug loading capabilities. The fabricated nanostructures in this study showed good dispersity, non-toxicity, and potential use as X-ray contrast agents, with significant effects on radiotherapy observed at high concentrations.
JOURNAL OF POROUS MATERIALS
(2021)
Article
Chemistry, Physical
Yufeng Wang, Greg M. Swain, G. J. Blanchard
Summary: This study reports on the surface charge-induced free charge density gradient and refractive index gradient in room-temperature ionic liquids (RTILs), as well as the relationship between the two. It demonstrates a modulation of refractive index of approximately 15% proportional to the surface charge density, providing new insights into the utility of RTILs for electro-optic applications.
JOURNAL OF PHYSICAL CHEMISTRY B
(2021)
Article
Chemistry, Multidisciplinary
Ju Hyang Park, Kyung Eun Sung, Ki Hak Kim, Jong Ryeol Kim, Jongbok Kim, Geon Dae Moon, Dong Choon Hyun
Summary: This work presents the fabrication of AuNR@MSNs with independent sensitivities to pH and NIR light for reversible drug release. The inclusion of thermosensitive and pH-sensitive gatekeepers allows controlled drug release under specific conditions.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Yue Cao, Ru Wu, Yuanzhen Zhou, Dechen Jiang, Wenlei Zhu
Summary: This article proposes a synthetic strategy inspired by the natural photosynthetic thylakoid membrane to construct hollow organic crystalline nanospheres. These nanospheres, obtained by hybridizing imine-linked COFs with polymeric hollow g-C3N4 nanospheres, can function as robust scaffolds, heterojunction shells, and light-harvesting antennas for efficient visible-light-driven photocatalysis. Additionally, a new electrochemiluminescence (ECL) technology is developed for in situ evaluation of the photodegradation process, enabling analysis and treatment of actual sewage.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Wenting Zheng, Hui Guo, Changqing Zhu, Cailiang Yue, Wenlei Zhu, Fuqiang Liu, Zhaoxu Chen
Summary: Through structural design and DFT calculations, Ce is predicted to enable the construction of CUCs in PBA, which can strongly adsorb H2O2 and produce (OH)-O• for O-O bond splitting. By preparing a binary Ce-Fe PBA, sulfamethoxazole degradation is significantly enhanced with high efficiency and stability. This work guides the whole process for highly active CUCs, enabling ultrafast and stable photo-Fenton catalysis.
ENERGY & ENVIRONMENTAL MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Xiaohan Yang, Kai Li, Guangtao Wang, Xiang Li, Pengyu Zhou, Shichao Ding, Zhaoyuan Lyu, Yu-Chung Chang, Yuanzhen Zhou, Wenlei Zhu
Summary: Currently, excessive consumption of fossil fuels leads to massive CO2 emissions, prompting the need for clean energy and decreased CO2 concentration. Photocatalytic technology shows promise for carbon dioxide conversion. This review focuses on the application of 2D materials in photocatalytic CO2 reduction, emphasizing the contribution of synthetic strategies to structure and performance, and discussing the current challenges and prospects for efficient photoreduction of CO2.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Review
Chemistry, Analytical
Linlin Wang, Wenlei Zhu, Jianrong Zhang, Jun-Jie Zhu
Summary: Electrochemical biosensors, utilizing enzymatic biofuel cells as energy and signal generators, have become a research hotspot due to their power self-support and simplified structure. Enzymatic biofuel cell-powered biosensors (EBFC-SPBs) have achieved tremendous success in health monitoring, but the miniaturization of portable EBFC-SPBs remains challenging. Microfluidic technology has significantly contributed to the progress of miniaturized and portable EBFC-SPBs. This review summarizes the achievements and progress in miniaturized EBFC-SPBs and discusses the advantages and challenges of microfluidic and screen-printing technologies for wearable and disposable EBFC-SPBs.
Article
Chemistry, Multidisciplinary
Huitong Du, Li-Xia Liu, Pan Li, Qianhao Min, Shaojun Guo, Wenlei Zhu
Summary: This study presents an effective strategy for enhancing propanol electro-synthesis from carbon monoxide (CO) reduction through a structural design of Cu2O nanoparticles. The multishell structured catalyst enriches C1 and C2 intermediates by nanoconfinement space, allowing for further coupling and achieving a high Faraday efficiency of 22.22 +/- 0.38% toward propanol at a current density of 50 mA cm-2.
Article
Chemistry, Multidisciplinary
Yue Cao, Jian-Xiao Wang, Chen Lin, Yu-Qian Geng, Cheng Ma, Jun-Jie Zhu, Leyong Wang, Wenlei Zhu
Summary: The ability to construct sensing platforms capable of selectively manipulating complex biological fluids is crucial for future advancements in healthcare. In this study, an electrochemiluminescence (ECL) transducer was developed by integrating protonated g-C3N4 and Ti3C2Tx MXene nanosheets, which exhibited enhanced charge injection/transfer and catalytic capacities for coreactant ECL. A mussel-inspired polydopamine was used as a surface-adherent substrate to coat the transducer, providing desired antifouling properties and ensuring minimal suppression of ECL performance. This highly integrated platform enabled high-performance exosome detection and tracking in a non-label manner. The study proposes a general design strategy for robust antifouling ECL sensing interfaces based on zwitterionic chemistries and provides new insights for the development of point-of-care and implantable ECL devices.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Analytical
Zhaoyuan Lyu, Shichao Ding, Lingzhe Fang, Xin Li, Tao Li, Mingjie Xu, Xiaoqing Pan, Wenlei Zhu, Yang Zhou, Dan Du, Yuehe Lin
Summary: In this study, a two-dimensional Fe-N-C-based single-atomic-site catalyst (2D Fe-SASC) with excellent peroxidase-like activity was successfully synthesized and used to design ELISA for herbicide detection. The 2D structure of Fe-SASC exposes numerous single atomic active sites on the surface, enhancing the sensing performance. The assembled 2D Fe-SASC into a competitive ELISA kit achieved excellent detection performance for 2,4-dichlorophenoxyacetic acid (2,4-D). Fe-SASC shows great potential to replace expensive natural enzymes and work on various advanced sensing platforms for the detection of different target biomarkers.
ANALYTICAL CHEMISTRY
(2023)
Article
Environmental Sciences
Beizhao Chen, Xun Liu, Bei Liu, Qi Han, Li Li, Li Wang, Yufei Shu, Linlin Zang, Wenlei Zhu, Zhongying Wang
Summary: Carbon nitride (CN) is a promising 2D non-metal semiconductor material for photocatalysis and advanced oxidation processes (AOPs). This study synthesized crystalline carbon nitride (CCN) and used it to activate peroxymonosulfate (PMS) under visible light to degrade tetracycline (TC) efficiently. CCN exhibited superior PMS activation compared to traditional polymeric carbon nitride (PCN) due to its increased crystallinity and catalytic sites. The generation of singlet oxygen (1O2) was found to be the dominant reactive oxygen species in the CCN/PMS/visible light system. This work reveals the potential of CCN-based materials for practical wastewater treatment.
Article
Environmental Sciences
Juntao Yang, Songbiao Tang, Bing Song, Yujing Jiang, Wenlei Zhu, Weihong Zhou, Gaixiu Yang
Summary: A comprehensive evaluation of the integration of anaerobic digestion (AD) and pyrolysis was conducted to enhance energy recovery. The accumulative CH4 yields increased from 33.23 to 249.20 mL/g VS as the AD time increased from 3 to 15 days. The highest energy efficiency of 71.9% and net energy gain of 2.0 MJ/kg wet biomass were achieved by the coupled system optimization at an AD time of 12 days. This study provides new insight for the maximal conversion of biomass waste into energy products and offers a new way of recycling it.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Multidisciplinary Sciences
Jing-Jin Lv, Zhe Li, Jiaju Fu, Wenlei Zhu
Summary: An electrochemical approach for ammonia production is developed by coupling the anodic dinitrogen oxidation reaction (NOR) and cathodic hydrogen evolution reaction (HER) within a membraneless flow electrolyzer. The obtained reactor shows preferential yield of ammonia over nitrogen oxides on the vanadium nitride catalyst surface. High ammonia production rate and Faradaic efficiency are achieved at an applied oxidation potential of 2.25 V versus the reversible hydrogen electrode (vs RHE).
Review
Engineering, Environmental
Zhuo Liu, Biyang Xu, Yu-Jing Jiang, Yang Zhou, Xiaolian Sun, Yuanyuan Wang, Wenlei Zhu
Summary: Methane, with a greenhouse effect much stronger than CO2, plays a significant role in global warming. Photocatalytic conversion of methane shows promise in reducing its concentration in the atmosphere, while also producing valuable chemicals and fuels. However, developing efficient and selective catalysts remains a challenge.
ACS ENVIRONMENTAL AU
(2023)
Article
Multidisciplinary Sciences
Ye Ye, Zhe Li, Shichao Ding, Jiaju Fu, Hongzhi Liu, Wenlei Zhu
Summary: This paper investigates the recent progress of electrocatalytic C-N coupling reactions and explores the potential of coupling CO2 reduction with nitrogen (N)-pollutants reduction. The technical concerns for scale-up applications of C-N coupling electrocatalysis are discussed, and the opportunities and challenges of applying C-N coupling electrocatalysis are prospectively analyzed.
Article
Chemistry, Multidisciplinary
Juan Liu, Xiaoxiao Guo, Zhaoyuan Lyu, Rong-Bin Song, Pengyu Zhou, Shichao Ding, Yang Zhou, Li-Ping Jiang, Yuehe Lin, Wenlei Zhu
Summary: By using copper electrocatalysts and microorganisms, an electro-bio tandem reactor was designed to convert CO2 into specific multicarbon compounds in both the gas and liquid phases. The reducing products from electrocatalysis can be consumed and recycled for selective acetate synthesis in Moorella thermoacetica. The results showed high faradaic selectivity for acetate in liquid products for Cu-based CO2 electroreduction and high electron conversion rate to ethylene and acetate for microbial electrosynthesis, presenting a green design for CO2 upcycling targeting multicarbon products through the parallel integration of electrocatalysis and fermentation.
Review
Energy & Fuels
Su Hui, Yujing Jiang, Yuanfan Jiang, Zhaoyuan Lyu, Shichao Ding, Bing Song, Wenlei Zhu, Jun-Jie Zhu
Summary: This paper systematically summarizes recent advancements in cathode materials in the field of electrocatalyst-assisted and photocatalyst-assisted microbial electrosynthesis (MES). Various material types are compared to investigate their effects on production rate and conversion efficiency. The paper also discusses the prospects for future development and practical applications of MES, providing theoretical guidance for the fabrication of cathode materials.
Review
Chemistry, Multidisciplinary
Liangyiqun Xie, Yujing Jiang, Wenlei Zhu, Shichao Ding, Yang Zhou, Jun-Jie Zhu
Summary: The massive emission of excess greenhouse gases has irreversible consequences on Earth's ecology. Electrocatalytic CO2 reduction, a technique that uses renewable energy sources to create highly reduced chemicals, has attracted significant attention. Cu-based catalysts have emerged as promising candidates for producing multi-carbon products with substantial value. This review explores state-of-the-art designs of Cu-based catalysts, enabling efficient multi-carbon generation in ECR by modulating reaction intermediates effectively.
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
