Article
Chemistry, Analytical
Joseph V. Goodwin, Benjamin T. Manard, Brian W. Ticknor, Paula Cable-Dunlap, R. Kenneth Marcus
Summary: The determination of actinide content and isotopics is important in nuclear forensics. This study demonstrates the use of high-resolution mass spectrometry to measure uranium isotope ratios in the presence of impurities without prior sample treatment.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Celia Venchiarutti, Rozle Jakopic, Carmel Hennessy, Kalman Toth
Summary: This paper introduces the preparation, characterisation, and validation of two QC samples for the measurement of plutonium and uranium contents using IDMS, emphasizing their use in line with ISO standards. It also highlights the use of these QC samples as part of an in-house spike inter-calibration campaign, and presents a detailed approach to IDMS uncertainty evaluation.
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
(2021)
Article
Chemistry, Analytical
Zsolt Varga, Adrian Nicholl, Maria Wallenius, Klaus Mayer
Summary: This study aimed to develop a direct method for age dating of uranium samples using laser ablation multi-collector inductively coupled plasma mass spectrometry (LA-MC-ICP-MS) by measuring the 230Th/234U ratio. The results showed that the LA-MC-ICP-MS method can produce accurate results for pure highly enriched uranium, but for natural and low-enriched uranium, a higher mass resolution is needed to remove identified interferences to avoid erroneous results.
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
(2023)
Article
Geosciences, Multidisciplinary
Suna Altundas
Summary: In-situ gamma-ray spectrometry measurements were conducted to study natural radionuclide variations and possible uranium migration in sandstone in the Central Anatolia Region and Deliler site in Yozgat, Turkey. The study found that uranium migration from granitic rocks to sandstones resulted in uranium enrichment in sandstone reservoir rocks. The method of radioactivity measurements proved to be a fast, economical, and effective way to determine areas of uranium enrichment due to migration.
JOURNAL OF APPLIED GEOPHYSICS
(2022)
Article
Chemistry, Analytical
Allison T. Greaney, Kathryn Peruski, Jason M. Richards, Susan K. Smith, Ramkumar Venkataraman, Glenn A. Fugate
Summary: A series of nondestructive assay measurements were performed on an industrial standard 12B cylinder of uranium hexafluoride to replicate dose variations previously observed on commercial 30B cylinders. The study found that less complex enrichment meter approaches were more robust than isotope ratio approaches.
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
(2021)
Article
Instruments & Instrumentation
Jonathan L. Burnett
Summary: Multidimensional gamma-spectrometry is a potential solution for safeguarding future thorium-fuelled molten salt reactors (MSRs). A high-sensitivity system developed at Pacific Northwest National Laboratory (PNNL), called Advanced Radionuclide Gamma spectrometer (ARGO), has successfully measured U-233 activity in freshly irradiated fuel salt samples using a dual-detector configuration and specific gamma-emissions. Accurate U-233 measurement was also demonstrated using coincident gamma-emissions. However, further improvements are needed for consistent determination of U-233 activity.
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
(2022)
Article
Chemistry, Analytical
Tae Hee Kim, Chan Jong Park, Hyun Young Kim, Haneol Lee, Jung-Youn Choi, Hana Seo
Summary: The goal of the project is to establish a baseline of nuclear material in domestic facilities through sample collection and analysis, in order to verify undeclared activities in the future.
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
(2021)
Article
Nuclear Science & Technology
Haneol Lee, Chan Jong Park
Summary: As the IAEA has implemented integrated safeguards and state-level approach, the importance of national inspections has grown. This research proposes an on-site U concentration analysis method to meet domestic notification requirements. The feasibility of this method is demonstrated through MCNP simulation and experiments, showing that it can effectively calculate U concentrations in UO2 pellets.
NUCLEAR ENGINEERING AND TECHNOLOGY
(2021)
Article
Instruments & Instrumentation
Ajeeta Khatiwada, Marc Klasky, Marcie Lombardi, Jason Matheny, Arvind Mohan
Summary: Gamma-ray spectroscopy is a quantitative, non-destructive technique for identifying and quantifying radionuclides. Machine learning algorithms provide an alternative method for analyzing gamma-ray spectroscopy data in emergency response, offering a reduction in steps and systematic uncertainties.
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
(2023)
Article
Physics, Multidisciplinary
A. Serban, A. Apostol, L. Ganea, A. Pantelica, D. Mirea, O. Sima
Summary: The study focused on non-destructive methods for characterizing depleted uranium based gamma defectoscopes for nuclear forensics, using High Resolution Gamma Spectrometry and X-Ray Fluorescence. The role of the National Nuclear Forensics Library in aiding data interpretation and furthering nuclear security investigations was also outlined.
ROMANIAN REPORTS IN PHYSICS
(2021)
Article
Engineering, Environmental
Ian Byrnes, Lisa Magdalena Rossbach, Jakub Jaroszewicz, Daniel Grolimund, Dario Ferreira Sanchez, Miguel A. Gomez-Gonzalez, Gert Nuyts, Estela Reinoso-Maset, Koen Janssens, Brit Salbu, Dag Anders Brede, Ole Christian Lind
Summary: Micro- and nanoscopic X-ray techniques were used to investigate the relationship between uranium tissue distributions and adverse effects on the digestive tract of Daphnia magna. The study showed that exposure to uranium nanoparticles (UNPs) resulted in adverse morphological changes to the midgut and hepatic ceca, as well as abnormal intestinal epithelial cells. High-resolution nano-XRF identified U particulates throughout the midgut and within hepatic ceca cells, coinciding with tissue damages. These findings highlight the importance of disrupted intestinal function as a mode of acute U toxicity in D. magna.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Spectroscopy
Jie Gao, Changkun Xu, Yonggang Zhao
Summary: A new technique combining SEM and TIMS was developed to measure the isotope ratios of individual uranium particles, showing good agreement with reference values and demonstrating the potential for becoming a promising alternative method for determining uranium isotope ratios in particle analysis. The method improves efficiency of sample preparation and simplifies the procedure, with relative errors and RSD within acceptable ranges for the measured isotope ratios.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Article
Materials Science, Multidisciplinary
Richard J. Wilbraham, Elizabeth A. Howett, Colin Boxall, David I. Hambley, Jessica K. Higgins
Summary: This paper presents a detailed study on the chemical and materials characterization of novel Simulated Spent Nuclear Fuels (SIMFuel) that replicate the state of Spent Nuclear Fuel (SNF) discharged from a UK Advanced Gas-cooled Reactor (AGR). The study evaluates the use of XPS, micro-Raman spectroscopy, and XRD in characterizing SIMFuels, and reveals the effects of lanthanide dopants on the UO2 bulk matrix. The findings suggest the presence of U(V) in the UO2 matrix as a means of charge compensation for the incorporation of Ln(III) states, and provide insights into the O/U ratios in SIMFuels.
JOURNAL OF NUCLEAR MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Kevin J. Pastoor, Michael J. Dzara, Svitlana Pylypenko, Jenifer C. Shafer, Mark P. Jensen
Summary: Uranium tetrafluoride (UF4) undergoes chemical speciation changes and forms hydrates when aged under high humidity conditions, indicating different hydration states depending on the temperature and relative humidity. These findings suggest that the presence of UF4 hydrate in UF4 materials may indicate storage under high humidity conditions.
JOURNAL OF NUCLEAR MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Rikard Malmbeck, Nidhu Lal Banik, Adrian Nicholl, Joan Horta-Domenech, Martin Vargas Zuniga, Klaus Luetzenkirchen
Summary: This work presents a method for accurately determining the concentration of Cm in a solution by spiking a Cm-244 solution with a known isotopic vector but unknown concentration, with a Pu reference standard. The concentration and activity of Cm-244 are determined by measuring the alpha peak ratio of Cm-244/Pu using alpha spectrometry. The method was found to have high precision, with an overall uncertainty of less than 0.67%.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Emin Yeltepe, Haluk Yucel
APPLIED RADIATION AND ISOTOPES
(2018)
Article
Nuclear Science & Technology
H. Yucel, O. Birgul, E. Uyar, S. Cubukcu
NUCLEAR ENGINEERING AND TECHNOLOGY
(2019)
Article
Nuclear Science & Technology
Haluk Yucel, Senem Zumrut, Recep Bora Nartturk, Gizem Gedik
NUCLEAR ENGINEERING AND TECHNOLOGY
(2019)
Article
Chemistry, Inorganic & Nuclear
O. Sima, A. De Vismes Ott, M. S. Dias, P. Dryak, L. Ferreux, D. Gurau, S. Hurtado, P. Jodlowski, K. Karfopoulos, M. F. Koskinas, M. Laubenstein, Y. K. Lee, M. C. Lepy, A. Luca, M. O. Menezes, D. S. Moreira, J. Nikolic, V. Peyres, P. Saganowski, M. I. Savva, R. Senunler, J. Solc, T. T. Thanh, K. Tyminska, Z. Tyminski, T. Vidmar, I. Vukanac, H. Yucel
APPLIED RADIATION AND ISOTOPES
(2020)
Article
Chemistry, Physical
Rukiye Durkan, Ayhan Gurbuz, Sema Murat, Haluk Yucel
RADIATION PHYSICS AND CHEMISTRY
(2020)
Article
Instruments & Instrumentation
Gizem Akkaya, Haluk Yucel, Mustafa Guray Budak
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS
(2020)
Article
Environmental Sciences
Haluk Yucel, Suleyman Ovuc, Gizem Akkaya, Sadiye Cakmak
RADIATION PROTECTION DOSIMETRY
(2020)
Correction
Environmental Sciences
Haluk Yucel, Suleyman Ovuc, Gizem Akkaya, Sadiye Cakmak
RADIATION PROTECTION DOSIMETRY
(2020)
Article
Nuclear Science & Technology
Haluk Yucel, Aziz Safi
Summary: The study investigated the tissue equivalency of a newly developed epoxy-based phantom in the paediatric energy range, finding that phantoms produced at a ratio of 10/90%G/A could effectively mimic a 3-year-old child's soft tissue. Measurements of HVL and HU values supported the potential use of these phantoms for quality control and dose optimization studies in medical X-ray systems.
NUCLEAR ENGINEERING AND TECHNOLOGY
(2021)
Article
Nuclear Science & Technology
Haluk Yucel, Selin Saatci Tuzuner, Charles Massey
Summary: This study presents a modified RID algorithm based on the Bayesian statistical method for medium energy resolution detectors. It applies the algorithm to uranium gamma-ray spectra analysis using a LaBr3:Ce detector. The algorithm estimates the posterior probability of each isotope in the ANSI library by extracting features from peak centroids and areas in the measured gamma-ray spectra. The algorithm's performance was validated with single isotopes and applied successfully to nuclear materials and natural ores.
NUCLEAR ENGINEERING AND TECHNOLOGY
(2023)
Article
Environmental Sciences
H. Yucel, R. Guven, I. Demirel
Article
Health Policy & Services
Mehmet Hursitoglu, Gulcin Sahingoz Erdal, Esra Akdeniz, Hakan Kocoglu, Nursel Kocamaz, Isil Ozbas Tevetoglu, Haluk Yucel, Ozlem Harmankaya, Aytekin Guven, Murat Akarsu, Tufan Tukek, Guzin Ozturk, Halil Dogan, Banu Karakus Yilmaz, Mehmet Emin Gunes, A. Baki Kumbasar
INTERNATIONAL JOURNAL OF HEALTH PLANNING AND MANAGEMENT
(2019)
Proceedings Paper
Physics, Multidisciplinary
Gizem Akkaya, Haluk Yucel, Mustafa Guray Budak
10TH JUBILEE CONFERENCE OF THE BALKAN PHYSICAL UNION
(2019)
Article
Chemistry, Inorganic & Nuclear
Haluk Yucel, R. Bora Nartturk, Senem Zumrut, Gizem Gedik, Mustafa Karadag
Article
Physics, Multidisciplinary
Kerem Duruer, Durmus Etiz, Haluk Yucel
EAST EUROPEAN JOURNAL OF PHYSICS
(2020)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).