Review
Chemistry, Analytical
Sayyed Hossein Hashemi, Massoud Kaykhaii
Summary: This article reviews the various applications, advantages and disadvantages of nano-coatings as media for micmextraction by stir bar, analyzing the critical evaluation of currently available methods. It is shown that using nano-coatings as coatings can improve the efficiency of stir bar sorption extraction.
Review
Biochemical Research Methods
Man He, Yuxin Wang, Qiulin Zhang, Lijuan Zang, Beibei Chen, Bin Hu
Summary: This review summarizes the recent progress of stir bar sorptive extraction (SBSE) in the past six years, focusing on the preparation methods and new materials for coated stir bars. The discussion also includes the development and prospects of SBSE as an efficient sample pretreatment technique in real sample analysis.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Chemistry, Applied
Ishwor Karki, Ping Li, Erik C. Vik, Alexander Manzewitsch, Evan Divirgilio, William E. Brewer, Ken D. Shimizu
Summary: A series of HLB polymers based on DVB and NVP with varying hydrophilicities were prepared using a robust monolith polymerization method. The highest binding capacity for polar analytes was observed in the monolith polymer prepared with the intermediate 30:70 NVP/DVB feed ratio, while hydrophobic polymers containing lower percentages of NVP were superior for the separation of non-polar analytes.
REACTIVE & FUNCTIONAL POLYMERS
(2021)
Article
Food Science & Technology
Sandra Marin-San Roman, Jose Miguel Carot-Sierra, Itziar Saenz de Urturi, Pilar Rubio-Breton, Eva P. Perez-Alvarez, Teresa Garde-Cerdan
Summary: This study optimized and compared the techniques of stir bar sorption extraction (SBSE) and multi-stir bar sportive extraction (mSBSE) for analyzing the volatile composition of grape must. The results showed that SBSE provided higher extraction of volatile compounds than mSBSE. The best conditions for SBSE were determined to be headspace extraction, 500 rpm speed, 6 hours extraction time, 60 degrees C temperature, and sequential NaCl addition.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Chemistry, Analytical
Victor Vallez-Gomis, Jose Grau, Juan L. Benede, Dimosthenis L. Giokas, Alberto Chisvert, Amparo Salvador
Summary: SBSDME is a novel microextraction technique that combines the principles of SBSE and DSPE, dispersing magnetic (nano)material into the sample solution through horizontal stirring, leading to improved extraction efficiency. It offers advantages of shorter extraction times and simplified processing in a single approach.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Aitor Sorribes-Soriano, Francesc Albert Esteve-Turrillas, Sergio Armenta, Jose Manuel Herrero-Martinez
Summary: In this study, a molecularly imprinted polymer (MIP)-coated stir bar for recognizing diazepam was prepared. The MIP was synthesized using methacrylic acid as a functional monomer, diazepam as a template, ethylene glycol dimethacrylate as a crosslinker, and azobisisobutyronitrile as an initiator. The resulting polymer-modified stir bar was characterized and used in a stir-bar-sorptive-extraction (SBSE) method in combination with ion mobility spectrometry (IMS) or ultra-high performance liquid chromatography coupled to mass spectrometry (UHPLC-MS/MS). The MIP-SBSE coupled with UHPLC-MS/MS showed satisfactory results in quantifying traces of diazepam in water samples, while the MIP-SBSE using IMS exhibited high sensitivity for rapid screening of the compound in different matrices.
MICROCHEMICAL JOURNAL
(2023)
Article
Food Science & Technology
Olga Vyviurska, Ha Anh Thai, Dominika Garancovska, Adriano A. Gomes, Ivan Spanik
Summary: Multi-SBSE is a viable alternative for sample preparation, improving data quality and enabling the identification of the geographical origin of botrytized wines. Multivariate optimization and PCA analysis were used to achieve discrimination of the wines.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Chemistry, Applied
David Munoz-Rodriguez, Yamile Perez-Padilla, Alejandro Avila-Ortega, Jesus Alberto Barron-Zambrano, Cristian Carrera-Figueiras
Summary: A translucent coating based on polydimethylsiloxane and aminopropyltriethoxysilane was prepared by a sol-gel method for stir bar sorptive extraction, successfully extracting and preconcentrating organic compounds from aqueous and organic samples. The coating was characterized as homogeneous, relatively polar, and thermally and chemically stable.
JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH
(2021)
Article
Chemistry, Analytical
Keran Su, Christina Shu Min Liew, Yunle Huang, Rui Min Vivian Goh, Aileen Pua, Jingcan Sun, Kim Huey Ee, Shao Quan Liu, Benjamin Lassabliere, Lionel Jublot, Bin Yu
Summary: In this study, an improved headspace-stir bar sorptive extraction was developed to extract volatile compounds with different polarities in a short time. Extraction conditions were selected and optimized using response surface methodology, and the addition of a cold stir bar further shortened the extraction time to 1 minute. The effect of different ethanol concentrations and salt additions on extraction efficiency was also studied, and 10% ethanol concentration with no salt addition provided the highest extraction efficiency for most compounds. The feasibility of the high-throughput extraction condition was verified using volatile compounds spiked in a honeybush infusion.
Article
Chemistry, Analytical
Francisco Antonio Casado-Carmona, Rafael Lucena, Soledad Cardenas
Summary: This article introduces the synthesis and application of a magnetic paper-based sorptive phase, which combines the sorption capacity of polyamide with the magnetic behavior of silica shielded Fe3O4 nanoparticles. The material is capable of extracting parabens and tri-closan from swimming pool water samples, with the convenience of easy transportation and on-site extraction. This innovation has the potential to simplify the analytical process by only transporting the sorptive phases, rather than the actual samples, to the lab for final analysis.
Article
Biochemical Research Methods
Jiaqi Liang, Felix Stoeppelmann, Zhigang Lu, Ann-kathrin Nedele, Yanyan Zhang
Summary: Stir bar sorptive extraction is effective for trapping odorants, and this study investigated the relationship between desorption conditions and efficiency for different odorants. Four machine learning models were trained using a dataset of four desorption conditions and physicochemical properties. The Random Forest model performed the best, and its prediction value was validated using a dataset of new odorants.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Chemistry, Analytical
Dandan Guo, Shuxin Yu, Nadeem Muhammad, Shaohua Huang, Yan Zhu
Summary: Poly amidoamine grafted composites were proposed as enrichment adsorption materials for the rapid and efficient adsorption of N-phosphoryl dipeptide. Controllability of surface functional groups and adsorption capacities of the composites were achieved by varying the generations of poly amidoamine dendrimers. Under optimized conditions, high selectivity and recovery efficiency were obtained, demonstrating good reproducibility in practical samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Peige Qin, Lizhen Han, Xiaowan Zhang, Mengyuan Li, Dan Li, Minghua Lu, Zongwei Cai
Summary: A magnetic porous carbon material with Fe3C nanoparticles encapsulated in porous carbon was prepared using MIL-101(Fe) as a carbon and Fe source through one-pot pyrolysis under N-2 atmosphere. The MPC-900 material showed the highest extraction ability for sulfonamides. By systematically studying the main parameters affecting the extraction process, favorable linearity and detection limits for sulfonamides were obtained. This method can effectively extract ultra-trace compounds in complex sample matrices.
Article
Chemistry, Applied
Daiki Kiyomichi, Celine Franc, Pierre Moulis, Laurent Riquier, Patricia Ballestra, Stephanie Marchand, Sophie Tempere, Gilles de Revel
Summary: Three compounds (2-acetyl-1-pyrroline, 2-acetyltetrahydropyridine, and 2-ethyltetrahydro-pyridine) have been identified as responsible for mousy off-flavor in wines. A simple method for quantifying these N-heterocyclic compounds simultaneously by SBSE-GC-MS was developed. This method provides lower detection and quantification limits compared to previously published concentrations in spoiled wine.
Article
Biochemical Research Methods
Mathieu Galmiche, Adeline Colin, Marie-Christelle Clavos, Christelle Pallez, Christophe Rosin, Xavier Dauchy
Summary: Nitroaromatic compounds were used in explosives during world wars and may still be present in the environment. A method for determining 28 nitroaromatic compounds in water was developed using stir bar sorptive extraction (SBSE), enabling sensitive quantification. The study detected up to 16 different nitroaromatic compounds in groundwater samples, with 2,4-DNT and 1,3-DNB showing the highest concentrations.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).