Alternative models in developmental toxicology

Zebrafish-As an integrative model for twenty-first century toxicity testing

(2011) Nisha S. Sipes et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Assessment of research models for testing gene–environment interactions

(2011) Amy L. Inselman et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The validated embryonic stem cell test to predict embryotoxicity in vitro

(2011) Andrea E M Seiler et al.   Nature Protocols

Evaluation of 309 Environmental Chemicals Using a Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity Assay

(2011) Kelly J. Chandler et al.   PLoS One

Zebrafish developmental toxicity assay: A fishy solution to reproductive toxicity screening, or just a red herring?

(2011) Kathleen Van den Bulck et al.   REPRODUCTIVE TOXICOLOGY

Mouse embryonic stem cell adherent cell differentiation and cytotoxicity (ACDC) assay

(2011) Marianne Barrier et al.   REPRODUCTIVE TOXICOLOGY

Predictive Models of Prenatal Developmental Toxicity from ToxCast High-Throughput Screening Data

(2011) Nisha S. Sipes et al.   TOXICOLOGICAL SCIENCES

Gene set assembly for quantitative prediction of developmental toxicity in the embryonic stem cell test

(2011) Jeroen L.A. Pennings et al.   TOXICOLOGY

Comparison of the mouse Embryonic Stem cell Test, the rat Whole Embryo Culture and the Zebrafish Embryotoxicity Test as alternative methods for developmental toxicity testing of six 1,2,4-triazoles

(2011) Esther de Jong et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Relative embryotoxicity of two classes of chemicals in a modified zebrafish embryotoxicity test and comparison with their in vivo potencies

(2011) Sanne A.B. Hermsen et al.   TOXICOLOGY IN VITRO

A different approach to validating screening assays for developmental toxicity

(2010) George P. Daston et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Development of a zebrafish embryo teratogenicity assay and quantitative prediction model

(2010) Kimberly C. Brannen et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Transcriptomics analysis of retinoic acid embryotoxicity in rat postimplantation whole embryo culture

(2010) Mirjam Luijten et al.   REPRODUCTIVE TOXICOLOGY

Metabolic activation capacity by primary hepatocytes expands the applicability of the embryonic stem cell test as alternative to experimental animal testing

(2010) Michael Hettwer et al.   REPRODUCTIVE TOXICOLOGY

The ReProTect Feasibility Study, a novel comprehensive in vitro approach to detect reproductive toxicants

(2010) Barbara Schenk et al.   REPRODUCTIVE TOXICOLOGY

Evaluation of Developmental Toxicant Identification Using Gene Expression Profiling in Embryonic Stem Cell Differentiation Cultures

(2010) Dorien A. M. van Dartel et al.   TOXICOLOGICAL SCIENCES

Embryotoxicant-Specific Transcriptomic Responses in Rat Postimplantation Whole-Embryo Culture

(2010) Joshua F. Robinson et al.   TOXICOLOGICAL SCIENCES

Monitoring Developmental Toxicity in the Embryonic Stem Cell Test Using Differential Gene Expression of Differentiation-Related Genes

(2010) Dorien A. M. van Dartel et al.   TOXICOLOGICAL SCIENCES

Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures

(2010) Dorien A.M. van Dartel et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate

(2009) Dorien A.M. van Dartel et al.   REPRODUCTIVE TOXICOLOGY

Development of a screening assay to identify teratogenic and embryotoxic chemicals using the zebrafish embryo

(2009) Ingrid W.T. Selderslaghs et al.   REPRODUCTIVE TOXICOLOGY

ReProGlo: A new stem cell-based reporter assay aimed to predict embryotoxic potential of drugs and chemicals

(2009) Frederik Uibel et al.   REPRODUCTIVE TOXICOLOGY

Transcriptomics-based identification of developmental toxicants through their interference with cardiomyocyte differentiation of embryonic stem cells

(2009) Dorien A.M. van Dartel et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Regulatory Compliance and the Zebrafish

(2009) Christian Lawrence et al.   Zebrafish

Species-specificity of ethylene glycol-induced developmental toxicity: toxicokinetic and whole embryo culture studies in the rabbit

(2008) Edward W. Carney et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Assessment of the Embryonic Stem Cell Test and application and use in the pharmaceutical industry

(2008) Jennifer A. Paquette et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

State of the art in developmental toxicity screening methods and a way forward: a meeting report addressing embryonic stem cells, whole embryo culture, and zebrafish

(2008) Robert Chapin et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Assessment of drug induced developmental toxicity using human embryonic stem cells

(2008) A MEHTA et al.   CELL BIOLOGY INTERNATIONAL

Successful validation of in vitro methods in toxicology by ZEBET, the National Centre for Alternatives in Germany at the BfR (Federal Institute for Risk Assessment)

(2008) Horst Spielmann et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Application of a metabolizing system as an adjunct to the rat whole embryo culture

(2008) Mirjam Luijten et al.   TOXICOLOGY IN VITRO

First steps in establishing a developmental toxicity test method based on human embryonic stem cells

(2007) Sarah Adler et al.   TOXICOLOGY IN VITRO