Journal
SYNTHETIC COMMUNICATIONS
Volume 44, Issue 21, Pages 3130-3138Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2014.928938
Keywords
alpha,alpha-Dihaloacetophenones; oxyhalogenation; persulfate salts; phenylacetylenes; water
Categories
Funding
- National Natural Science Foundation of China [21372068, J1210040, J1103312]
- Presidential Scholarship for Doctoral Students, Hunan University
Ask authors/readers for more resources
A novel K2S2O8-mediated oxy-1,1-dihalogenation of alkynes with NaX in the presence of water has been developed, affording alpha,alpha-dihaloacetophenones in moderate to good yields. The advantages of this reaction are mild reaction conditions, operational simplicity, and use of pure water as reaction medium. A plausible reaction mechanism is proposed on the basis of mechanistic studies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available