Journal
SYNTHETIC COMMUNICATIONS
Volume 43, Issue 7, Pages 1023-1029Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2011.621096
Keywords
Chalcone; flavanone; green chemistry; liquiritigenin; tetrahydroquinolone
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Funding
- Ministry of Education of the People's Republic of China [208119]
- Natural Science Foundation Project of CQ [CSTC, 2011BA5025]
- Innovative Research Team Development Program in University of Chongqing [KJTD201020]
- 100 leading scientists promotion project of Chongqing
- Chongqing Technology and Business University [yjscxx2009-07]
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Highly efficient and green catalytic conversion of 2'-hydroxy and 2'-amino chalcones to flavanones and tetrahydroquinolones is reported herein. 2'-Hydroxy and 2'-amino chalcones can be almost completely converted to flavanones and tetrahydroquinolones in just 2 min in the presence of piperidine and KOH under room temperature. Liquiritigenin is also efficiently synthesized under similar conditions.
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