Journal
SYNTHETIC COMMUNICATIONS
Volume 43, Issue 3, Pages 361-374Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2011.599103
Keywords
Ball milling; N-deformylation; polyglycols; quinolines; solid-state synthesis
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Funding
- National Natural Science Foundation of China [20876147]
- Natural Science Foundation of Zhejiang Province [Y4090346]
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The emerging technique of high-speed ball milling was first applied in the N-deformylation and aromatization reaction to synthesize quinolines. PEGs (polyglycols) were used to promote this solvent-free, solid-solid state reaction and good to excellent yields of the quinolines were obtained in short reaction times.
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