Journal
SYNTHETIC COMMUNICATIONS
Volume 41, Issue 4, Pages 583-588Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911003629457
Keywords
Asymmetric hydrogenation; cyclic -aminoesters; cyclic -enaminoesters; ruthenium
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Funding
- Wirtschaftsministerium von Mecklenburg-Vorpommern
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[image omitted] Ethyl 2-(N-methylformate-1,4,5,6-tetrahydropyridin-2-yl) acetate with endocyclic double bond was prepared with high regioselectivity and further reduced into (R)-N-protected homopipecolate with a good enantioselectivity using chiral ruthenium catalyst.
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