4.3 Article

Reductive Amination of Aldehydes and Ketones Under Heterogeneous and Solvent-Free Conditions Using Sodium-Borohydride and Silica-Gel-Supported Sulfuric Acid

Journal

SYNTHETIC COMMUNICATIONS
Volume 39, Issue 16, Pages 2907-2916

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802691882

Keywords

Heterogeneous system; one-pot reaction; reductive amination; solvent free

Funding

  1. Mazandaran University, Iran

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A regioselective and convenient procedure for preparation of amines by reductive amination of aldehydes and ketones using sodium borohydride in the presence of sulfuric acid supported on silica gel as an active, inexpensive, and recoverable catalyst under heterogeneous and solvent-free conditions at room temperature is described.

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