4.3 Article

Efficient one-pot synthesis of 2-carbonyl-1-indanols by palladium-catalyzed tandem Heck-aldol reaction

Journal

SYNTHETIC COMMUNICATIONS
Volume 38, Issue 15, Pages 2662-2671

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910601038731

Keywords

2-carbonyl-1-indanol; Morita-Baylis-Hillman adducts; one-pot; palladium-catalyzed

Funding

  1. Shenyang BMD Chemical Co., Ltd.

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2-Carbonyl-1-indanols were synthesized in moderate to good yields by the reaction of orthohalogenated aryl aldehyde with Morita-Baylis-Hillman adducts via a one-pot, palladium-catalyzed tandem Heck-aldol reaction. Various Morita-Baylis-Hillman adducts were examined to find the scope and limitations of this process.

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