Journal
SYNTHESIS-STUTTGART
Volume 44, Issue 13, Pages 1977-1982Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0031-1291125
Keywords
S-benzyl isothiouronium chloride; reductive amination; ketones; amines; hydrogen bond
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Funding
- Sabbatical Research Program of Chonnam National University
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The direct reductive amination of ketones using the Hantzsch ester in the presence of S-benzyl isothiouronium chloride as a recoverable organocatalyst is reported. A wide range of ketones as well as amines were found to give the expected products in moderate to excellent yields.
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