Journal
SYNTHESIS-STUTTGART
Volume -, Issue 5, Pages 764-768Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1258422
Keywords
2-aminoindole-3-carboxylates; 2-aminoindole-3-carbonitriles; N-(2-iodophenyl)formamides; copper(I) iodide; coupling
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An efficient method for the synthesis of 2-aminoindole-3-carbonitriles and 2-aminoindole-3-carboxylates by the reaction of N-(2-iodophenyl)formamides with malononitrile and cyanoacetates, respectively, in the presence of a catalytic amount of copper(I) iodide using potassium carbonate as a base is reported.
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