4.4 Article

Selective Reduction of Halogenated Nitroarenes with Hydrazine Hydrate in the Presence of Pd/C

Journal

SYNLETT
Volume 25, Issue 10, Pages 1403-1408

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1339025

Keywords

reduction; nitroarenes; hydrazine hydrate; palladium on carbon; aromatic amines; transfer hydrogenation

Funding

  1. National Institutes of Health [T32 GM008804]
  2. University of Arizona
  3. Caldwell Health Sciences Research Fellowship

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A large variety of halogenated nitroarenes have been selectively reduced with hydrazine hydrate in the presence of Pd/C to give the corresponding (halogenated) anilines in good yield.

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