Journal
SYNLETT
Volume 25, Issue 1, Pages 12-32Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1340073
Keywords
ethers; heterocycles; natural products; total synthesis; cyclization; ring closure
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Funding
- Spanish MINECO
- European Regional Development Fund (ERDF) [CTQ2011-28417-C02-01/BQU, CTQ2011-22653]
- IMBRAIN project [FP7-REGPOT-2012-CT2012-31637-IMBRAIN]
- Seventh Framework Programme (CAPACITIES)
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This account describes our studies on the synthesis of natural products that contain cyclic ethers in their structures. An overview of the main methodologies is presented and several total syntheses developed by the group are described. We also discuss new applications based on the use of Prins and Nicolas reactions as key steps in the preparation of oxygenated heterocyclic compounds.
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