Article
Chemistry, Multidisciplinary
Yanyan Yu, Wanke Cheng, Yilin Li, Tong Wang, Qinqin Xia, Yongzhuang Liu, Haipeng Yu
Summary: The use of diol-tailored deep eutectic solvents allows for efficient fractionation of lignocellulose and maximizes the efficiency of refinery. This method achieves near-quantitative extraction of cellulose from lignocellulose, while simultaneously solubilizing lignin and hemicellulose. Additionally, the hemicellulose can be selectively converted to useful products and the lignin can be recovered for synthesis of other chemicals. This work demonstrates the importance of tailored deep eutectic solvent fractionation in lignocellulose refinery.
Article
Chemistry, Organic
Dayong Sang, Huaxin Yue, Yang Fu, Juan Tian
Summary: A one-pot procedure for deprotecting carboxylic esters under nonhydrolytic conditions is described, involving the use of aluminum powder and iodine in anhydrous acetonitrile. This method enables the selective cleavage of alkyl carboxylic esters without affecting aryl esters, showcasing its practical significance.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Beatrice Casali, Elisabetta Brenna, Fabio Parmeggiani, Francesca Tentori, Davide Tessaro
Summary: This paper investigates the valorization of soapstock from high-oleic sunflower oil refinement through biocatalytic methods, achieving efficient soapstock splitting and oleic acid oxidation, resulting in the production of commercially valuable products.
Article
Chemistry, Multidisciplinary
Yongil Kim, Matthias Kunzel, Dominik Steinle, Xu Dong, Guk-Tae Kim, Alberto Varzi, Stefano Passerini
Summary: Seawater batteries store energy by using pure sodium metal as the negative electrode, without the need for a specific host material. The sodium metal is harvested from seawater and converted into energy through charge and discharge processes. The compact and metal-less design of the battery achieves high energy efficiency.
ENERGY & ENVIRONMENTAL SCIENCE
(2022)
Article
Chemistry, Organic
Subhabrata Sen, Dhiraj Barman, Haya Khan, Ranajit Das, Debajit Maiti
Summary: An efficient copper-catalyzed solvent-free multi component reaction for the synthesis of pyridine derivatives, iodonium ylides, and 1,4-quinones has been developed using a room-temperature ball milling technique. This method provides a sustainable and scalable synthesis with good yields and can be used as a fluorescent chromophore-based cellular probe.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Subhankar Kundu, Subhajit Saha, Subhra Jyoti Panda, Chandra Shekhar Purohit, Bhaskar Biswas
Summary: This study focuses on the design, synthesis, spectroscopic characterization and catalytic phosphoesterase cleavage activity of two isostructural and isomorphous complexes containing a new synthetic ligand. The X-ray crystallography reveals that both complexes adopt nearly a perfect square planar geometry and display a high degree of similarity. The copper complex exhibits a higher turnover frequency for hydrolysis compared to the nickel complex. Mechanistic interpretation suggests the crucial role of coordinated water in facilitating the nucleophilic attack on the phosphorous center.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Organic
Hayato Fujimoto, Shisato Yamamura, Momoka Kusano, Mamoru Tobisu
Summary: We presented the phosphine-catalyzed 1,2-diacylation of alkynes using acyl fluorides and acylsilanes as acyl sources. The reaction relies on a formal oxidative addition-ligand metathesis-reductive elimination cycle based on phosphine redox catalysis, enabling the selective introduction of two different acyl groups into alkynes.
Article
Chemistry, Physical
Vicente Dorado, Clara I. Herrerias, Jose M. Fraile
Summary: The tandem/sequential combination of epoxidation and hydrogenolysis for unsaturated fatty esters is complex due to incompatibility problems with impurities in the solvents used. The use of isobutyl acetate as a solvent resulted in an 85% yield of hydroxystearates from methyl oleate in a sequential process.
APPLIED CATALYSIS A-GENERAL
(2021)
Article
Chemistry, Multidisciplinary
Zihao Wang, Yizhuo Lu, Jinxiang Yang, Wei Xiao, Tianyou Chen, Changfeng Yi, Zushun Xu
Summary: Hydrophobic environments significantly influence the catalytic performance of artificial catalytic triads, but are often overlooked. A simple strategy to engineer the hydrophobic environment in polystyrene-supported artificial catalytic triad nanoparticles was developed. The influence of chemical structures and constituent ratios of hydrophobic copolymers on catalytic performance was studied, demonstrating potential applications for the hydrolysis of carboxylic esters.
Article
Pharmacology & Pharmacy
John Garner, Sarah Skidmore, Justin Hadar, Haesun Park, Kinam Park, Young Kuk Jhon, Bin Qin, Yan Wang
Summary: This study focuses on separating PLGAs based on their molecular properties, such as L:G ratio, molecular weight, and comonomer sequence, using semi-solvents that dissolve only PLGAs with lactide contents above a certain threshold. The mechanism study of semi-solvents indicates a preference for PLGAs with relatively higher L%, lower molecular weight, and higher G-L sequences. The ability to separate and identify PLGA fractions allows better characterization of existing formulations and higher flexibility in designing new injectable, long-acting PLGA formulations.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Chemistry, Physical
Dawei Xia, Ethan Phillip Kamphaus, Anyang Hu, Sooyeon Hwang, Lei Tao, Sami Sainio, Dennis Nordlund, Yanbao Fu, Haibo Huang, Lei Cheng, Feng Lin
Summary: We provide design criteria for dilute ether electrolytes that can support reversible graphite anodes by tailoring solvation structures and thermodynamic properties. Our redesigned electrolyte consisting of 1,3-dioxolane (DOL) solvent and lithium bis(fluorosulfonyl)imide (LiFSI) salt weakens Li-solvent interaction and results in an inorganic-rich solid electrolyte interphase, achieving high Coulombic efficiency and capacity retention. The weakly solvated electrolyte maintains desirable transport properties and enables better rate capability than carbonate electrolytes.
ACS ENERGY LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Hongmei Xie, Guozhi Zhu, Dawei Ye, Weiquan Cai, Junjie Zhang, Kangping Huang, Yuliang Mai, Bing Liao, Jiazhi Chen
Summary: This study reports for the first time the conversion of Tung nutshell lignin to value-added C/G-type aromatic monomers using the catalytic oxidation strategy with the commercially available CuCl2 catalyst. The optimal yield of C/G-type aromatic aldehydes and acids was achieved at 60.8 mg g-1 (or 12.9 wt%) using the CuCl2 catalyst in the CH3CN/H2O solvent mixture at 190°C for 4 hours. The CuCl2/CH3CN/H2O catalytic oxidative system effectively depolymerized and transformed C/G units into aromatic aldehydes and acids.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Agricultural Engineering
Chen Huang, Yunni Zhan, Jinyuan Cheng, Jia Wang, Xianzhi Meng, Xuelian Zhou, Guigan Fang, Arthur J. Ragauskas
Summary: The study shows that the addition of trace AlCl3 during the enzymatic degradation process using DES can significantly enhance the degradation of hemicellulose and lignin, improving the enzymatic digestibility of pretreated plant fibers. Alkali washing is a feasible method to remove the precipitated lignin after degradation, which can significantly increase the enzymatic hydrolysis efficiency of the materials.
BIORESOURCE TECHNOLOGY
(2021)
Article
Engineering, Environmental
Ke Zhang, Kun-Pu Ho, Anamika Chatterjee, Grace Park, Zhiyao Li, Jeffrey G. Catalano, Kimberly M. Parker
Summary: RNA, as a biomolecule essential for life, plays a central role in biogeochemical processes and emerging technologies across environmental systems. In this study, a previously unreported abiotic pathway of RNA hydrolysis on iron-oxide minerals was revealed, demonstrating a rapid degradation process occurring within hours. The hydrolysis was facilitated by the presence of iron in the minerals acting as a Lewis acid. This mineral-catalyzed hydrolysis of RNA may have significant implications for nucleic acid analysis in environmental systems.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Food Science & Technology
Yuan Yuan, Congcong Cui, Hui Liu, Xuenan Li, Yue Cao, Yan Zhang, Haiyang Yan
Summary: This study found that the type of oil, temperature, time, salt content, and frying cycle all significantly influence the levels of MCPD esters in Chinese fried dough sticks. Additionally, a strong positive correlation was observed between 3-MCPD esters and 2-MCPD esters, indicating the former could serve as a representative index for MCPD esters. Moreover, changes in the levels of MCPD esters were attributed to oxidation and hydrolysis of oil during the frying process.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Organic
Chad N. Ungarean, Jeremy D. Mason, Benjamin R. Eyer, Nicholas S. Duca, Jaimie M. Mong, S. Shaun Murphree
SYNTHESIS-STUTTGART
(2017)
Article
Chemistry, Organic
Jeremy D. Mason, Steven M. Weinreb
JOURNAL OF ORGANIC CHEMISTRY
(2018)
Article
Chemistry, Multidisciplinary
Cianan B. Russell, Jeremy D. Mason, Theodore G. Bean, S. Shaun Murphree
JOURNAL OF CHEMICAL EDUCATION
(2014)
Article
Chemistry, Organic
Nathan R. Haines, Aaron N. VanZanten, Anthony A. Cuneo, John R. Miller, William J. Andrews, David A. Carlson, Ryan M. Harrington, Adam M. Kiefer, Jeremy D. Mason, Julie A. Pigza, S. Shaun Murphree
JOURNAL OF ORGANIC CHEMISTRY
(2011)
Article
Chemistry, Organic
S. Shaun Murphree, Jeremy D. Mason, Theodore G. Bean, Michelle C. Perry
SYNTHETIC COMMUNICATIONS
(2012)
Article
Chemistry, Multidisciplinary
Jeremy D. Mason, Daniel W. Terwilliger, Aditya R. Pote, Andrew G. Myers
Summary: A gram-scale synthesis of ibooxycin, an antibiotic candidate with a fused bicyclic amino acid residue, was successfully developed. Key transformations in the route include intramolecular hydrosilylation-oxidation sequence for ring-fusion stereocenters and high-yielding, highly diastereoselective alkylation of a pseudoephenamine amide. This synthetic strategy provided ample quantities of ibooxycin for in vivo profiling in murine models of infection.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Multidisciplinary Sciences
Matthew J. Mitcheltree, Amarnath Pisipati, Egor A. Syroegin, Katherine J. Silvestre, Dorota Klepacki, Jeremy D. Mason, Daniel W. Terwilliger, Giambattista Testolin, Aditya R. Pote, Kelvin J. Y. Wu, Richard Porter Ladley, Kelly Chatman, Alexander S. Mankin, Yury S. Polikanov, Andrew G. Myers
Summary: The lack of new medicines effective against antibiotic-resistant bacteria is a growing concern in global public health. The traditional semisynthesis method for finding new antibiotics is inadequate in combating rapidly evolving resistance threats, while fully synthetic routes designed properly can address this issue. Through structure-guided design and component-based synthesis, a new antibiotic named iboxamycin has been developed with exceptional potency and spectrum of activity against various bacteria.
Meeting Abstract
Chemistry, Multidisciplinary
Jeremy Mason, Steven Weinreb
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2018)
Article
Chemistry, Multidisciplinary
Jeremy D. Mason, Steven M. Weinreb
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2017)
