Journal
SYNLETT
Volume -, Issue 9, Pages 1364-1370Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0031-1290962
Keywords
2-aryl-4-quinazolinone; hypervalent iodine reagent; acetoxylation; C-H activation
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Funding
- CSIR
- UGC, New Delhi
- King Saud University for Global Research Network for Organic Synthesis (GRNOS)
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2-Aryl-4-quinazolinones undergo smooth acetoxylation in the presence of 5 mol% Pd(OAc)(2) and a stoichiometric amount of PhI(OAc)(2) via C-H activation to produce the corresponding acetoxy-substituted 4(3H)-quinazolinone derivatives in good yields with high regioselectivity.
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