Journal
SYNLETT
Volume -, Issue 16, Pages 2420-2424Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1261229
Keywords
NHC; fully substituted furans; umpolung; solvent-free synthesis; multicomponent reaction
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Funding
- Natural Science Foundation of the Jiangsu Higher Education Institutions [09KJA430003]
- Natural Science Foundation of Xuzhou City [XM09B016]
- Graduate Foundation of Xuzhou Normal University [2010YLB029]
- Qing Lan Project [08QLT001]
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An efficient synthesis of 2,3-diarylated fully substituted furans was performed through the sequential reactions of Knoevenagel reaction, Stetter reaction catalyzed by NHC, and intramolecular cyclization under solvent-free conditions. The protocol has the advantages of easy workup, high yields, and an environmental benign procedure compared with the reported methods.
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