Article
Agriculture, Dairy & Animal Science
Wenya Du, Zhuliang Yang, Cong Xiao, Yongcui Liu, Jiashuo Peng, Jianneng Li, Fuqiu Li, Xiurong Yang
Summary: In this study, we investigated the molecular basis of variations in skin appendages by observing the morphogenesis of feathered feet, scaled feet, and wings skin in Longsheng-Feng chickens and Guangxi Partridge chickens. Through transcriptome sequencing and analysis, we identified candidate genes associated with feathered feet, including TBX5 and PITX1, and hypothesized their involvement in hair follicle development through the Wnt/β-catenin signaling pathway. These findings provide a theoretical basis for understanding the molecular regulatory mechanisms underlying the formation of chicken feathered feet.
Article
Agriculture, Dairy & Animal Science
Haoqiang Ye, Zhenqiang Xu, Semiu Folaniyi Bello, Qianghui Zhu, Shaofen Kong, Ming Zheng, Xiang Fang, Xinzheng Jia, Haiping Xu, Xiquan Zhang, Qinghua Nie
Summary: In this study, the performance of haplotype models for genomic prediction in a Chinese yellow-feathered chicken population was comprehensively evaluated. It was found that haplotype methods were beneficial for genomic prediction, and the accuracy could be further increased by incorporating genomic annotation information. Moreover, using LD information would potentially improve the performance of genomic prediction.
Article
Genetics & Heredity
Zhuliang Yang, Leqin Zou, Tiantian Sun, Wenwen Xu, Linghu Zeng, Yinhai Jia, Jianping Jiang, Jixian Deng, Xiurong Yang
Summary: This study identified SNPs and INDELs associated with comb traits in Nandan-Yao chickens through GWAS, revealing a significant region on chromosome 6 and candidate genes such as FGFR2 and CYB5R2. These findings could accelerate genetic improvement of comb development through marker-assisted breeding.
FRONTIERS IN GENETICS
(2021)
Article
Physiology
Xiaojing Liu, Lu Liu, Jie Wang, Huanxian Cui, Guiping Zhao, Jie Wen
Summary: FOSL2 was identified as a key gene related to muscle glycogen (MG) content in chickens. Through differential gene expression analysis and WGCNA, several other genes associated with MG metabolism pathway were also identified. Lentiviral overexpression of FOSL2 was found to decrease the glycogen content in DF1 cells, confirming its crucial role in the regulation of MG content in chickens.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Physiology
Fuli Kong, Guiping Zhao, Zhengxiao He, Jiahong Sun, Xicai Wang, Dawei Liu, Dan Zhu, Ranran Liu, Jie Wen
Summary: This study confirmed compression force as a quantitative indicator for differentiating breast filets and identified serum CK as a potential biomarker for predicting wooden breast in live broilers to aid genetic selection in broiler breeding.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Genetics & Heredity
Siyuan Xing, Ranran Liu, Guiping Zhao, Martien A. M. Groenen, Ole Madsen, Lu Liu, Maiqing Zheng, Qiao Wang, Zhou Wu, Richard P. M. A. Crooijmans, Jie Wen
Summary: The study investigated the gene expression in the liver of slow-growing meat type chickens at different developmental stages, identifying key genes associated with abdominal fat deposition. The results suggested that ACSBG2 gene among others could be used as a candidate gene for selecting chickens with low abdominal fat weight.
FRONTIERS IN GENETICS
(2021)
Article
Genetics & Heredity
Xiaodong Tan, Lu Liu, Xiaojing Liu, Huanxian Cui, Ranran Liu, Guiping Zhao, Jie Wen
Summary: This study investigated the genetic architecture and key variants associated with breast muscle weight (BrW) in Jingxing yellow chickens. The researchers identified high-impact single nucleotide polymorphisms (SNPs) and muscle-related genes through genome-wide association study and integrated analysis. They also discovered a major haplotype and a crucial gene, IGF2BP1, associated with BrW.
Article
Genetics & Heredity
Yuxi Jin, Xiaoya Yuan, Wenjuan Zhao, Hua Li, Guiping Zhao, Jianfeng Liu
Summary: This study identifies key genes and pathways related to the formation of hexanal using gene expression analysis and co-expression network analysis. The results show that differentially expressed genes and hub genes are enriched in various signaling pathways, including the PPAR signaling pathway and the MAPK signaling pathway. These findings are important for understanding and further researching genes related to hexanal content.
Article
Genetics & Heredity
Jiahong Sun, Xiaodong Tan, Xinting Yang, Lu Bai, Fuli Kong, Guiping Zhao, Jie Wen, Ranran Liu
Summary: This study identifies candidate genes associated with chicken meat color by comparing fast-growing, white-feathered chickens and slow-growing, yellow-feathered chickens. The findings contribute to the understanding of the molecular mechanisms regulating meat color and the development of molecular markers for chicken meat color selection.
Article
Microbiology
Mamadou Thiam, Astrid Lissette Barreto Sanchez, Jin Zhang, Jie Wen, Guiping Zhao, Qiao Wang
Summary: This study revealed the association between H/L ratio and Salmonella resistance, and proposed a method for selecting and breeding Salmonella-resistant chickens.
Article
Agriculture, Dairy & Animal Science
Zhengxiao He, Sen Li, Wei Li, Jiqiang Ding, Maiqing Zheng, Qinghe Li, Alan G. Fahey, Jie Wen, Ranran Liu, Guiping Zhao
Summary: This study compared the GBLUP model and GA-BLUP model with previously identified associated SNPs. The GA-BLUP model with nine RFI-associated SNPs showed improved prediction accuracy compared to the GBLUP model.
Article
Biotechnology & Applied Microbiology
Na Luo, Jingting Shu, Xiaoya Yuan, Yuxi Jin, Huanxian Cui, Guiping Zhao, Jie Wen
Summary: By studying the deposition of IMF and AF in chicken meat, the study revealed the regulatory mechanisms of crucial genes and signaling pathways in their deposition, providing a theoretical basis for producing high-quality broilers.
Article
Agriculture, Dairy & Animal Science
Xiaodong Tan, Ranran Liu, Wei Li, Maiqing Zheng, Dan Zhu, Dawei Liu, Furong Feng, Qinghe Li, Li Liu, Jie Wen, Guiping Zhao
Summary: This study demonstrates the effective use of genomic selection (GS) for improvements in body weight and meat production in a chicken line. The study also identifies genomic regions and genes that are influenced by intensive genetic selection.
Article
Genetics & Heredity
Astrid Lissette Barreto Sanchez, Qiao Wang, Mamadou Thiam, Zixuan Wang, Jin Zhang, Qi Zhang, Na Zhang, Qinghe Li, Jie Wen, Guiping Zhao
Summary: This study evaluated the heat tolerance and identified potential driver and hub genes related to heat stress in native and commercial chicken breeds through phenotypical, physiological, liver transcriptome comparative analysis and WGCNA. The results showed that native chickens were less affected by heat stress and had fewer differentially expressed genes (DEGs) related to metabolism activity, while commercial chickens had pathways related to inflammatory reactions. CPT1A and ANGPTL4 were identified as candidate genes associated with heat stress in native chickens, while HSP90B1 and HSPA5 were identified in commercial chickens. TLR7, AR, and BAG3 genes were revealed as hub genes playing an important role in heat stress.
Article
Agriculture, Dairy & Animal Science
Jiqiang Ding, Fan Ying, Qinghe Li, Gaomeng Zhang, Jin Zhang, Ranran Liu, Maiqing Zheng, Jie Wen, Guiping Zhao
Summary: Genetic analyses on 11,279 chickens from seven material lines identified a genomic region associated with egg number in meat-type chickens, as well as 29 SNPs and 9 candidate genes potentially affecting egg production traits.
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Qiao Wang, Jin Zhang, Hailong Wang, Zixuan Wang, Qinghe Li, Guiping Zhao, Maiqing Zheng, Jie Wen
Summary: Runs of homozygosity (ROHs) are effective for assessing inbreeding and detecting selection in livestock populations. This study investigated the occurrence and distribution of ROHs, compared genomic inbreeding coefficients, and identified genomic regions with high ROH frequencies in different Beijing-You chicken populations. The findings contribute to understanding genetic diversity and population demography.
Article
Agriculture, Dairy & Animal Science
G. M. Zhang, P. H. Liu, L. Chen, J. M. Zheng, G. P. Zhao, W. H. Xing, J. Wen, Q. H. Li
Summary: Researchers identified genome-wide significant markers on chromosome 7 related to semen volume in white-feathered broilers, and four candidate genes (FAPP1, OSBPL6, SESTD1, and SSFA2) potentially involved in semen volume were identified. These findings may contribute to further research on the genetic mechanism and marker-assisted selection of semen volume in white-feathered broilers.
Article
Agriculture, Dairy & Animal Science
Wei Li, Maiqing Zheng, Guiping Zhao, Jie Wang, Jie Liu, Shunli Wang, Furong Feng, Dawei Liu, Dan Zhu, Qinghe Li, Liping Guo, Yuming Guo, Ranran Liu, Jie Wen
Summary: Background feed contributes to the majority of costs in poultry meat production, making feed efficiency a critical factor. This study identified genetic parameters and QTL for feed efficiency in purebred broilers through a genome-wide association study. Candidate genes related to mitochondrial function and behavioral regulation were identified, suggesting their potential role in growth and feed efficiency in poultry.
GENETICS SELECTION EVOLUTION
(2021)
